View all show notes and timestamps on the KoopCast website.

Episode overview:

Originally released on October 14, 2021.

Nick Tiller Research is a fellow at the Lundquist Institute at Harbor-UCLA where he studies clinical respiratory and exercise physiology, and the physiology / pathophysiology of ultra-endurance exercise. He is also a columnist at Skeptical Inquirer Magazine, and the author of The Skeptic's Guide to Sports Science.

Episode highlights:

(20:01) Recap of potential cardiovascular health effects: athletes who train high volumes are not at risk, races and high intensity training are more likely to be problematic, the emergent state of ultramarathon research

(27:20) Respiratory risks of racing ultras: chronically no different than other endurance sports, drops in acute lung function, most are not clinically significant, asthma or other conditions mean you start from a lower baseline and can experience clinically significant problems

(35:23) The renal system: UTMB health policy, banning NSAIDs, duration, heat, altitude, dehydration, and hyponatremia all compound, NSAIDs make everything worse, acute kidney dysfunction in ultras is common and generally non harmful, chronic effects are unknown

Additional resources:

Potential Long-Term Health Problems Associated with Ultra-Endurance Running: A Narrative Review-https://www.researchgate.net/publication/354387155_Potential_Long-Term_Health_Problems_Associated_with_Ultra-Endurance_Running_A_Narrative_Review
Nick’s Interview on Triathlete magazine-https://www.triathlete.com/culture/the-fight-against-pseudoscience-and-bad-training-advice-in-endurance-sports/
Nick’s Book: The Skeptic’s Guide to Sports Science-https://www.amazon.com/Skeptics-Guide-Sports-Science-Confronting/dp/1138333123
SUBSCRIBE to Research Essentials for Ultrarunning-https://www.jasonkoop.com/research-essentials-for-ultrarunning
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