"Second Opinion" with Christina Farr, Ash Zenooz MD & Luba Greenwood JD

Luba Greenwood and Ash Zenooz discuss the evolving biotech landscape, the impact of AI on drug discovery, the importance of using real-world evidence in drug development, and personal motivations for continuing efforts in the biotech field. For full show notes, visit: https://highlightai.com/share/f4d42739-65df-42d9-a6b4-6c1327705d7a 

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SPONSORS:

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LINKS:

Gallup Oncology: https://www.galloponcology.com/

PureTech Health: https://www.puretechhealth.com/ 

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FOLLOW:

https://www.linkedin.com/in/christinafarr/ 

https://www.linkedin.com/in/lubagreenwood/ 

https://www.linkedin.com/in/ashzenooz/

Christina Farr, Ash Zenooz, and Luba Greenwood are joined by Zeke Emanuel, a prominent oncologist, bioethicist, and influential voice in healthcare to discuss the impact of GLP-1 drugs, healthcare affordability, Trump's appointments, and AI in medicine. The second half of the episode was recorded a week after Trump's election victory. For full show notes, visit: https://highlightai.com/share/dd71470c-2a01-4cfa-a011-5597a86efdf5

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RECOMMENDED PODCAST: Unpack Pricing

Dive into the dark arts of SaaS pricing with Metronome CEO Scott Woody and tech leaders. Learn how strategic pricing drives explosive revenue growth in today's biggest companies like Snowflake, Cockroach Labs, Dropbox and more.

Apple: https://podcasts.apple.com/us/podcast/id1765716600

Spotify: https://open.spotify.com/show/38DK3W1Fq1xxQalhDSueFg

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SPONSOR:

📝Notion offers powerful workflow and automation templates, perfect for streamlining processes and laying the groundwork for AI-driven automation. With Notion AI, you can search across thousands of documents from various platforms, generating highly relevant analysis and content tailored just for you - try it for free at notion.com/upstreampod

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https://www.linkedin.com/in/ashzenooz/

Christina Farr and Ash Zenooz discuss the recent departures of prominent female CEOs from major healthcare companies and explore why progress in female leadership representation has been challenging in the healthcare industry. For full show notes, visit: https://highlightai.com/share/f0e550de-d7d5-49bd-96ea-700dde222ccc 

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📰 Be notified early when Turpentine drops new publication: https://www.turpentine.co/exclusiveaccess  

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RECOMMENDED PODCAST:

🎙️ Unpack Pricing - Dive into the dark arts of SaaS pricing with Metronome CEO Scott Woody and tech leaders. Learn how strategic pricing drives explosive revenue growth in today's biggest companies like Snowflake, Cockroach Labs, Dropbox and more.

Apple: https://podcasts.apple.com/us/podcast/id1765716600

Spotify: https://open.spotify.com/show/38DK3W1Fq1xxQalhDSueFg

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LINKS:

HLTH: https://www.hlth.com/ 

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FOLLOW:

https://www.linkedin.com/in/christinafarr/

https://www.linkedin.com/in/lubagreenwood/

https://www.linkedin.com/in/ashzenooz/

In this episode of Second Opinion, hosts Christina Farr, Ash Zenooz, and Luba Greenwood interview Rob Perez, founder of Life Science Cares, about his work bridging the biotech industry with poverty alleviation efforts. For full show notes, visit: https://highlightai.com/share/f3eb77b0-b71c-40fe-817e-bd3c1b4dc5b4 

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RECOMMENDED PODCAST:

🎙️ Unpack Pricing - Dive into the dark arts of SaaS pricing with Metronome CEO Scott Woody and tech leaders. Learn how strategic pricing drives explosive revenue growth in today's biggest companies like Snowflake, Cockroach Labs, Dropbox and more.

Apple: https://podcasts.apple.com/us/podcast/id1765716600

Spotify: https://open.spotify.com/show/38DK3W1Fq1xxQalhDSueFg

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LINKS:

Life Science Cares: https://lifesciencecares.org/

Project OnRamp: https://lifesciencecares.org/project-onramp/

Subscribe to Second Opinion Newsletter: https://secondopinion.media/ 

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FOLLOW:

https://www.linkedin.com/in/rob-perez-93707916/ 

https://www.linkedin.com/in/christinafarr/

https://www.linkedin.com/in/lubagreenwood/

https://www.linkedin.com/in/ashzenooz/

Dr. Lloyd Minor, Dean of Stanford School of Medicine joins Christina Farr, Ash Zenooz, and Luba Greenwood to discuss the various transformative advancements and challenges in healthcare, focusing on the equitable use of AI and technology to enhance patient care, improve medical training, and address labor shortages. They dive into AI’s role in imaging, pathology, and electronic health records, as well as innovative approaches in medical education. 

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LINKS: 

Stanford Medicine: https://med.stanford.edu/

RAISE Health: https://med.stanford.edu/raisehealth 

Subscribe to Second Opinion Newsletter: https://secondopinion.media/  

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FOLLOW

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TIMESTAMPS:

(00:00) Intro

(03:50) Challenges in healthcare and potential solutions

(06:49) AI in medical practice

(11:01) The future of medical education

(19:33) Encouraging careers in medicine

(28:56) Preventative care and health policy

(31:46) Advances in cancer treatment

(32:48) Innovations in early diagnosis and preventative strategies

(33:18) Challenges in the US healthcare system

(34:17) Reflections on academic leadership during Covid-19

(35:50) Stanford's response to the Covid-19 crisis

(38:49) Balancing academic freedom and public health

(40:37) Practical solutions during the pandemic

(41:20) Innovations in healthcare

(42:37) The future of ai and digital health

(49:11) The debrief

In this episode of Second Opinion, Christina Farr, Ash Zenooz, and Luba Greenwood discuss the integration and evaluation of digital tools in healthcare with guest Caroline Pearson from the Peterson Health Technology Institute. They explore the challenges in demonstrating clinical effectiveness and affordability of digital health solutions, using diabetes management tools as a case example. They address the role of evidence in the healthcare system, potential biases in standard evaluation practices, and the need for improved data sharing between digital health companies and traditional healthcare providers.

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LINKS: 

Peterson Health Technology Institute: https://phti.org/

Peterson Center on Healthcare: https://petersonhealthcare.org/ 

Nonlinear dynamics of multi-omics profiles during human aging: https://www.nature.com/articles/s43587-024-00692-2 

New Report Finds That Digital Diabetes Management Tools Fail to Deliver Meaningful Health Benefits to Patients While Increasing Spending: https://phti.org/announcement/new-report-finds-that-digital-diabetes-management-tools-fail-to-deliver-meaningful-health-benefits-to-patients-while-increasing-spending/ 

Subscribe to Second Opinion Newsletter: https://secondopinion.media/  

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TIMESTAMPS:

(00:00) Intro

(01:39) Discussion about super aging

(02:54) Introducing Caroline Pearson

(04:16) Challenges in digital health solutions

(05:58) The role of evidence in digital health

(16:41) Employer-sponsored health insurance concerns

(20:05) Collaboration and data sharing in health tech

(32:05) The future of health tech and patient outcomes

(33:30) Conclusion and final thoughts

(34:37) The debrief

In this episode of Second Opinion, Christina Farr, Ash Zenooz, and Luba Greenwood discuss the evolving landscape of healthcare leadership with Oxeon CEO Sonia Millsom. They explore what makes a great healthcare CEO, covering current talent market trends, qualities of successful leaders, and the valuable roles of executive chairs in a company. Sonia offers invaluable insights into the art of relationship-building, the importance of rigorous candidate evaluation, and the strategic decision-making that fuels successful hiring and partnerships

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RECOMMENDED PODCAST: 

🎙️Turpentine VC

Investor Erik Torenberg interviews partners at the top VCs in the world to learn their approach to the art and science of building a successful venture firm.

Apple: https://podcasts.apple.com/us/podcast/id1701006772

Spotify: https://open.spotify.com/show/3Yb8ErLRnyoAqn4Y6NegTx

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LINKS: 

Oxeon: https://www.oxeon.com/

Subscribe to Second Opinion Newsletter: https://secondopinion.media/  

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https://www.linkedin.com/in/sonia-millsom-a1b993a/ 

https://www.linkedin.com/in/christinafarr/

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https://www.linkedin.com/in/ashzenooz/

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TIMESTAMPS:

(00:00) Intro

(03:28) Current market dynamics and talent trends

(06:04) Challenges and changes in the C-suite

(12:38) The reality of being a first-time CEO

(15:53) Hot and cold: trends in healthtech

(19:40) Negotiating offers and equity

(23:06) Understanding company valuations

(24:52) Breaking into the tech industry

(26:17) Advisory work and board positions

(27:14) Challenges and importance of board chairs

(28:37) Effective interviewing and hiring practices

(30:59) The human element in recruitment

(38:05) The debrief

In this episode of the Second Opinion Podcast, Christina Farr, Ash Zenooz, and Luba Greenwood engage in a candid conversation with Dr. Isaac (Zak) Kohane, a renowned AI expert and chair at Harvard Medical School's Department of Biomedical Informatics. 

Zak expresses his optimism about AI in healthcare, sharing personal anecdotes to illustrate how tools like ChatGPT can enhance patient care by providing detailed and understandable information, and highlights AI's potential to address healthcare system gaps by complementing human doctors. They explored regulatory issues, data privacy concerns, and the importance of patient control over their health data, while emphasizing the need for a balanced approach that prioritizes patient care and ethical guidelines.

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LINKS: 

Department of Biomedical Informatics at Harvard Medical School: https://dbmi.hms.harvard.edu/ 

NEJM AI, a journal from the publishers of the New England Journal of Medicine: https://www.nejm.org/ 

The AI Revolution in Medicine: GPT-4 and Beyond: https://www.amazon.com/AI-Revolution-Medicine-GPT-4-Beyond-ebook/dp/B0BXNVM6FC

AMIE: A research AI system for diagnostic medical reasoning and conversations: https://research.google/blog/amie-a-research-ai-system-for-diagnostic-medical-reasoning-and-conversations/ 

Medical Artificial Intelligence and Human Values: https://www.nejm.org/doi/full/10.1056/NEJMra2214183 

Transformer: A Novel Neural Network Architecture for Language Understanding: https://research.google/blog/transformer-a-novel-neural-network-architecture-for-language-understanding/ 

Subscribe to Second Opinion Newsletter: https://secondopinion.media/  

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FOLLOW:

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TIMESTAMPS:

(00:00) Intro

(02:24) Skepticism in advanced technology

(04:56) AI in Medicine: Personal Anecdotes

(07:29) Challenges in healthcare access

(08:26) The role of ai in patient empowerment

(11:26) Human clinicians vs. AI

(19:45) Sponsor: Awell

(20:57) Privacy concerns with AI

(25:13) HIPAA compliance and medical data

(26:19) Bias and alignment in AI models

(29:00) The role of AI in medical decision making

(33:13) Challenges in AI regulation

(38:21) The future of AI in healthcare

(43:56) Wrap

(45:05) The Debrief

In this episode of Second Opinion, Christina Farr is joined by Carine Carmy, CEO of Origin to discuss the overlooked aspects of women's healthcare, a case for a physical clinic, and funding stigmatized fields within the complex healthcare landscape. Carine shares valuable insights on scaling the business, the importance of evidence-based care, and the future of pelvic health, including the potential impact of AI and digital health.

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RECOMMENDED PODCAST:

🎙️This Won't Last

Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel. They unpack their hottest takes on the future of tech, business, venture, investing, and politics.

Apple Podcasts: https://podcasts.apple.com/us/podcast/this-wont-last-with-keith-rabois-kevin-ryan-logan/id1765665937

Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSz

YouTube: https://www.youtube.com/@ThisWontLastpodcast 

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SPONSOR:

AWELL

Transform your healthcare operations with Awell! Say goodbye to manual work and Excel hell. Awell's CareOps orchestration platform helps design, implement, and improve care flows in days. Trusted by Astrana Health, Commons Clinic, and Better Health, Awell automates processes for faster care model improvements in 2 days or less. Visit awellhealth.com and mention Second Opinion for a free bootcamp.

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LINKS:

Subscribe to Second Opinion Newsletter: https://secondopinion.media/ 

Origin: https://www.theoriginway.com/ 

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FOLLOW:

https://www.linkedin.com/in/carinecarmy/ 

https://www.linkedin.com/in/christinafarr/

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TIMESTAMPS:

(00:00) Intro

(01:43) The origin story of Origin

(03:31) Challenges in women's health

(04:02) Understanding pelvic floor therapy

(05:10) Pain and gaslighting in healthcare

(07:39) Building a business in women's health

(10:16) Navigating health plan coverage

(13:51) Sponsor: Awell

(15:02) Scaling and fundraising challenges

(17:42) Clinic setup and expansion

(25:36) The importance of evidence-based care

(29:05) Wrap

In this episode of Second Opinion, hosts Christina Farr, Ash Zenooz, and Luba Greenwood dive into the intricacies of the behavioral health industry with Alex Katz, CEO of Two Chairs. They discuss the misconceptions and challenges within the mental health system, the importance of finding the right therapeutic fit, and the impact of venture capital in driving both quality and accessibility in mental health services. Alex highlights the need for personalized care, the evolving perception of therapy thanks to platforms like TikTok, and the potential and limitations of AI in therapy, emphasizing the irreplaceable value of human therapists.

—

RECOMMENDED PODCASTS:

🎙️This Won't Last

Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel. They unpack their hottest takes on the future of tech, business, venture, investing, and politics.

Apple Podcasts: https://podcasts.apple.com/id1765665937

Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSz

YouTube: https://www.youtube.com/@ThisWontLastpodcast

🎙️Turpentine VC

Investor Erik Torenberg interviews partners at the top VCs in the world to learn their approach to the art and science of building a successful venture firm.

Apple: https://podcasts.apple.com/us/podcast/id1701006772

Spotify: https://open.spotify.com/show/3Yb8ErLRnyoAqn4Y6NegTx

—

SPONSOR: AWELL

Transform your healthcare operations with Awell! Say goodbye to manual work and Excel hell. Awell's CareOps orchestration platform helps design, implement, and improve care flows in days. Trusted by Astrana Health, Commons Clinic, and Better Health, Awell automates processes for faster care model improvements in 2 days or less. Visit awellhealth.com and mention Second Opinion for a free bootcamp.

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LINKS:

Subscribe to Second Opinion Newsletter: https://secondopinion.media/ 

Two Chairs: http://www.twochairs.com/ 

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FOLLOW:

https://www.linkedin.com/in/alexjkatz/ 

https://www.linkedin.com/in/christinafarr/

https://www.linkedin.com/in/lubagreenwood/

https://www.linkedin.com/in/ashzenooz/

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TIMESTAMPS:

00:00 Intro

01:14 Behavioral health industry insights

02:04 Alex Katz's journey with Two Chairs

05:02 Navigating the mental health landscape

08:22 Business models in mental health

14:04 Barriers to mental health access

16:08 Sponsor: Awell

19:56 Behavioral health companies and cost reduction

22:00 The crisis in therapy retention

23:41 Youth mental health challenges

25:40 Gen Z and therapy culture

29:14 The importance of hybrid care models

31:31 Skepticism around ai therapists

36:00 The Debrief