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Calvary Baptist Church in Findlay, Ohio: Audio messages and radio broadcasts including the *This Is My Story* project

Glimpses of Calvary » Podcast Feed

PreCalculus

A 10-week read-along study through the book "The Gospel in the Marketplace of Ideas: Paul's Mars Hill Experience for Our Pluralistic World" by Paul Copan & Kenneth D. Litwak.

A 10-week read-along study through the book "The Gospel in the Marketplace of Ideas: Paul's Mars Hill Experience for Our Pluralistic World" by Paul Copan &amp; Kenneth D. Litwak.

Read Along with Apologetics 315

Free monthly Australian night sky mp3 audio guides, produced by Sydney Observatory. Published at the beginning of each month, usually around 20 minutes long, and including information about what you are likely to be able to see in that month's Australian night sky, including constellations, stars, the Sun, Moon, planets, astronomy, telescopes and astronomical mythology.

Australian monthly night sky guides

Oracle Radio is a learning platform for exemplary leadership. Join in stimulating, interactive discussions with other like-minded individuals. Access recently recorded shows from iTunes or listen here on BlogTalkRadio. For previously recorded shows visit www.ritmo.shinshuri.com or www.oraclesoftruth.org.

OracleRadio

Multiculturalism is one of the most vexing political issues of our day. How can people with very different values and customs live alongside each other? What is the history of multiculturalism? What are the arguments for and against its various forms? Has it failed? Does it have a future? The Open University's Nigel Warburton interviews ten leading thinkers about the meaning and implications of multiculturalism. David Edmonds introduces each episode.

Multiculturalism Bites - Audio

Sinneswandel ist ein Podcast zwischen Philosophie und Popkultur. Die Journalistin Marilena Berends spricht über Sinnsuche, Kreativität, Selbstzweifel, gesellschaftliche Brüche und das Leben im Dauerwandel. Sie denkt laut über Themen wie Nachhaltigkeit, Sinn, Zukunft der Arbeit oder gesellschaftliche Veränderungen nach. Dabei verbindet sie persönliche Beobachtungen mit philosophischen Gedanken. Menschen und Geschichten stehen im Mittelpunkt – sie zeigen, wie wir anders denken und handeln können, wenn wir wollen.

Sinneswandel

Your Faith to Live By speakers are Larry Millender and James Saulter.  Larry is the senior pastor of Church 360 in Tallahassee, with Sunday services at 9 a.m. and Wednesday services at 6:30 p.m.  James is the senior pastor of Summit Life Church in Crawfordville, with Sunday morning morning prayer at 8 a.m. and worship at 10:30 a.m.  And Wednesday Life Group is at 7 p.m.

Your Faith to Live By speakers are Larry Millender and James Saulter. Larry is the senior pastor of Church 360 in Tallahassee, with Sunday services at 9 a.m. and Wednesday services at 6:30 p.m. James is the senior pastor of Summit Life Church in Crawfordville, with Sunday morning morning prayer at 8 a.m. and worship at 10:30 a.m. And Wednesday Life Group is at 7 p.m.

Faith to Live By with Pastor Larry Millender of Church 360 in Tallahassee Florida - Abundant Life in Christ

Life is what it is, and if you can come to understand that part, you'll be able to figure out the next part. And that's how to enjoy it, you only get one life to live and how you live it is so crucial, not only to you but for the generations after. Here's a few things to remember 

1) Take the time to learn something new as much as possible because with knowledge itself, there's nothing you can solve. 
"Rakim"

2) There will always be some that will focus on your past to criticize your present.But will always undestimate your future.
"Crawford Dupree Murray Jr"

Life is good, Enjoy it❤️

Life is what it is, and if you can come to understand that part, you'll be able to figure out the next part. And that's how to enjoy it, you only get one life to live and how you live it is so crucial, not only to you but for the generations after. Here's a few things to remember 1) Take the time to learn something new as much as possible because with knowledge itself, there's nothing you can solve. "Rakim" 2) There will always be some that will focus on your past to criticize your present.But will always undestimate your future. "Crawford Dupree Murray Jr" Life is good, Enjoy it❤️

It's Time To Enjoy Yourself And Be Happy (Knowledge, Wisdom And Understanding Is Key) Remember That

The Lollygagging Podcast with Rick and Dave - language learning for intermediate and advanced learners covering topics of interest for polyglots and language-learners.

Lollygagging

How do young children learn, and how can adults help them? This album looks at how nursery teachers support children in their development. We follow a practitioner’s day, looking at how she works with children, observes and plans for further activities while she also records her thoughts and ideas using a video camera.  Further video tracks reveal how creativity is nurtured in young children to develop their abilities, how an artist in residence works with nursery children, as well as how the work of bilingual and special needs assistants mean that no child is excluded from the learning process. The audio tracks cover the importance of parental input, and the fantastic opportunities available to develop children’s creativity using technologies. This material forms part of The Open University course E124 Supporting children’s learning in the early years.

How do young children learn, and how can adults help them? This album looks at how nursery teachers support children in their development. We follow a practitioner’s day, looking at how she works with children, observes and plans for further activities while she also records her thoughts and ideas using a video camera. Further video tracks reveal how creativity is nurtured in young children to develop their abilities, how an artist in residence works with nursery children, as well as how the work of bilingual and special needs assistants mean that no child is excluded from the learning process. The audio tracks cover the importance of parental input, and the fantastic opportunities available to develop children’s creativity using technologies. This material forms part of The Open University course E124 Supporting children’s learning in the early years.

Supporting children’s learning in the early years - for iPod/iPhone

İngilizce öğretmeni ve yazar Seçkin Esen'in anlatımıyla baştan sona tüm İngilizce konularını dinleyin ve pratik yapın.
Seçkin Esen tarafından yazılan İngilizce kitapları:
- Temel İngilizce Dil Bilgisi
- Develop Your Grammar
- Advance Your Grammar
- Advance Your Vocabulary
- Website: seckinesen.com
- Youtube: youtube.com/seckinesen
- Online İngilizce Kursları: udemy.com/user/seckin-esen
- İngilizce Kelime Uygulaması: wordismo.com

İngilizce öğretmeni ve yazar Seçkin Esen'in anlatımıyla baştan sona tüm İngilizce konularını dinleyin ve pratik yapın. Seçkin Esen tarafından yazılan İngilizce kitapları: - Temel İngilizce Dil Bilgisi - Develop Your Grammar - Advance Your Grammar - Advance Your Vocabulary - Website: seckinesen.com - Youtube: youtube.com/seckinesen - Online İngilizce Kursları: udemy.com/user/seckin-esen - İngilizce Kelime Uygulaması: wordismo.com

İngilizce Dersleri

Universal: Including or covering all or a whole collectively
 Folklore: Traditional customs, tales, sayings, dances or art forms preserved among people.

 
Everyone has a story to tell, and more often than not I find that our stories are similar enough to unite us. Before this podcast started, I would seek models out to sit for an hour or two. I would draw their portrait while we shared a conversation. It felt like every time I did this I would walk away with a broader world view. The experience was too good not to share.
 
The goal of Universal Folklore: To sit down with people from all walks of life to talk about their passions and learn their stories, with the hope of inspiring people and showing that we all have much more in common than we think.
 
Let's break bread.

Universal: Including or covering all or a whole collectively Folklore: Traditional customs, tales, sayings, dances or art forms preserved among people. Everyone has a story to tell, and more often than not I find that our stories are similar enough to unite us. Before this podcast started, I would seek models out to sit for an hour or two. I would draw their portrait while we shared a conversation. It felt like every time I did this I would walk away with a broader world view. The experience was too good not to share. The goal of Universal Folklore: To sit down with people from all walks of life to talk about their passions and learn their stories, with the hope of inspiring people and showing that we all have much more in common than we think. Let's break bread.

Universal Folklore

Это подкаст о нашем будущем. О том, что происходит в мире, и как технологии его меняют. 
Мои гости - эксперты из разных сфер и отраслей, которые делятся своим рассуждениями и мыслями о том, что нас ждет впереди.

Facebook: @sandugash.rakhimzhanova
Instagram: @vasandi
E-mail: sandusha.r@gmail.com
Aitube: https://aitube.page.link/uJsu

Это подкаст о нашем будущем. О том, что происходит в мире, и как технологии его меняют. Мои гости - эксперты из разных сфер и отраслей, которые делятся своим рассуждениями и мыслями о том, что нас ждет впереди. Facebook: @sandugash.rakhimzhanova Instagram: @vasandi E-mail: sandusha.r@gmail.com Aitube: https://aitube.page.link/uJsu

Будущее уже сегодня

Award-winning author, speaker, and humanitarian, Linda Rendleman hosts What’s Next for Women Like Us. Listen to important conversations with women who are leading the way toward authenticity and actualization. You'll get tips and resources that can get you on your way to create your most astounding future as Linda and her guests deep dive into personal stories and shared strategies for reaching your authentic life.

Award-winning author, speaker, and humanitarian, Linda Rendleman hosts What’s Next for Women Like Us. Listen to important conversations with women who are leading the way toward authenticity and actualization. You'll get tips and resources that can get you on your way to create your most astounding future as Linda and her guests deep dive into personal stories and shared strategies for reaching your authentic life.

Award-winning author, speaker, and humanitarian, Linda Rendleman hosts What’s Next for Women Like Us. Listen to important conversations with women who are leading the way toward authenticity and actualization. You'll get tips and resources that can get you on your way to create your most astounding future as Linda and her guests deep dive into personal stories and shared strategies for reaching your authentic life.

What's Next For Women Like Us

Un Mental Hack es un atajo para reprogramar nuestra perspectiva, una estrategia que permite optimizar la forma en que pensamos y tomamos decisiones. ¡Siempre digo que lo que necesitamos es FOCO! De la inspiración de "Ataraxia on the radio", resignifiqué este concepto y lo transformé en MENTAL HACKS. ¿List@ para hackear tu mente? ¡Welcome aboard!

Mental Hacks Podcast

Gang, Gang, Gang WELCOME to my Podcast Peons I am and will always be your favorite Goddess Dria But you can call me Goddess it’s a lot easier trust. On this Podcast you will be getting my honest and true self with all my wierd and quirky ways. So yeah tune in I care and pop just pop my shit sometimes with guest sometimes with myself just to y’all and sometimes idk I just do what I want on my podcast. Come through like your partner saying Baby Come on and let me love you down and that’s on that this just the intro come for a listen stay for a lifetime. I’m the OG 4Lifer you wanna stay with😘😍

Dria’s Diary

Editor, writing coach and applied linguist, Dr Lizzy Tanguay chats with guests about everything you need to know about writing for business. Subscribe now for weekly writing tips, tricks and motivation.

Let's talk writing. Writing for educators and coaches.

Bringing free game, good vibes, and talent ReBlaze Of SLMSS LLC ! Follow 8Tv on Instagram @8tvpodcast ! Subscribe To 8Tv On YouTube @8Tvpodcast ! Follow 8tvpodcast On TikTok !

8Tv Podcast

Welcome to the 99 Ways to Win Network where we’re Seeking Your Success as Christian women and mothers dealing with mental health, ADHD and the craziness of this modern world.  

Text JOIN to 682.738.5393 for helpful tips, encouragement and notifications of upcoming shows and virtual meet-ups! //        

The Falon & Michelle Show - 
Get ready to laugh, learn, have a gut check and maybe even cry...all in the same episode! Michelle Wright and Falon Sells use truth, transparency and humor to uncover joy amidst the craziness of life. This dynamic duo tackles everything from mental health and motherhood to relationships and spiritual growth, all from a Christian perspective.

Welcome to the 99 Ways to Win Network where we’re Seeking Your Success as Christian women and mothers dealing with mental health, ADHD and the craziness of this modern world. Text JOIN to 682.738.5393 for helpful tips, encouragement and notifications of upcoming shows and virtual meet-ups! // The Falon & Michelle Show - Get ready to laugh, learn, have a gut check and maybe even cry...all in the same episode! Michelle Wright and Falon Sells use truth, transparency and humor to uncover joy amidst the craziness of life. This dynamic duo tackles everything from mental health and motherhood to relationships and spiritual growth, all from a Christian perspective.

Welcome to the 99 Ways to Win Network where we’re Seeking Your Success as Christian women and mothers dealing with mental health, ADHD and the craziness of this modern world.  

Text JOIN to 682.738.5393 for helpful tips, encouragement and notifications of upcoming shows and virtual meet-ups! //        

The Falon &amp; Michelle Show - 
Get ready to laugh, learn, have a gut check and maybe even cry...all in the same episode! Michelle Wright and Falon Sells use truth, transparency and humor to uncover joy amidst the craziness of life. This dynamic duo tackles everything from mental health and motherhood to relationships and spiritual growth, all from a Christian perspective.

99 Ways to Win Network

Discussing some of lifes harder to discuss or hard to hear topics, in an effort to show the world that you are not alone in this fight. With truth comes acceptance and a path to recovery. 

Find us on Facebook: https://www.facebook.com/hardtruthpodcast
Or Twitter: https://twitter.com/MindWaveLina

To become a Hard Truther and join our community head on over to https://www.patreon.com/hardtruthpod

Discussing some of lifes harder to discuss or hard to hear topics, in an effort to show the world that you are not alone in this fight. With truth comes acceptance and a path to recovery. Find us on Facebook: https://www.facebook.com/hardtruthpodcast Or Twitter: https://twitter.com/MindWaveLina To become a Hard Truther and join our community head on over to https://www.patreon.com/hardtruthpod

Hard Truth

We all have "Gaps" that prevent us from growing. Our mission is to empower you to close those gaps by increasing your awareness, confidence and clarity. Join Luke and Caty Rinehart and learn to close the gap between where you are and where you want to be!

Closing the Gap Growth Podcast

Two friends and Foreign Service moms discuss chaos and wellness amidst life abroad. Chats about mindfulness, imperfection, parenting, struggle and connection--friends take a closer look at the thoughts that hang out in the basement of their brains (the dark ones we all like to hide). Welcome to our deep thoughts...

BRAIN BASEMENT

The Safety Church podcast is a platform where Salvation and Workplace Safety collide! Join host Terry Gray as he discuses the need that people of faith fill in the safety community. As a pastor and advocate for safety, Terry shares the parallels that exist between safety principles and biblical principles. Prepare to be inspired and informed on subjects that will build your faith and character both spiritually and professionally. Terry expresses the impact that safety and salvation can have when combined to help improve the workplace environment. Safety Church will open your eyes to the affects that christians in safety have and can have when you let you light shine for Christ in the safety industry. This is intended for safe workers everywhere trying to do whats right for safety. We are on a mission… Saving Souls and Saving Lives!!

The Safety Church Podcast

Hosted by Parish Rawlins, this podcast is for all clinicians to align, build, and grow, personally and professionally. 
Each episode dives into mindset, confidence, and clinical reasoning, blending real-life insights with practical strategies. 
Expect honest reflections, powerful mentoring moments, and tools to help you thrive, not just survive in healthcare. 
Whether you're an OT, physio, nurse, or allied health professional, tune in for inspiration, empowerment, and connection every step of the way!

Follow on Instagram @parish.rawlins

Hosted by Parish Rawlins, this podcast is for all clinicians to align, build, and grow, personally and professionally. Each episode dives into mindset, confidence, and clinical reasoning, blending real-life insights with practical strategies. Expect honest reflections, powerful mentoring moments, and tools to help you thrive, not just survive in healthcare. Whether you're an OT, physio, nurse, or allied health professional, tune in for inspiration, empowerment, and connection every step of the way! Follow on Instagram @parish.rawlins

The Passion Occupational Therapy Podcast

Urdu Bagh (اُردُو بَاغ - उर्दू बाग़) is a celebration of the Urdu language in its many facets. This podcast series showcases the work of Urdu legends, scholars, and activists. It also explores anecdotal history, celebrating the lives and works of Urdu’s literary giants, primarily through the memories of their family members, friends, historians, and activists. The series ‘Urdu Bagh’ is available on all major podcast platforms. Presented and produced by Pervaiz Alam for London-based Cine Ink, a hub for podcasts in Hindi and Urdu, the series is also accessible on major social media platforms, including Twitter, Facebook, Instagram, and LinkedIn. All Cine Ink podcasts can be found on its website, <a href="http://www.cineink.com/" target="_blank" rel="noreferrer noopener">www.cineink.com</a>. You can reach us at: post@cineink.com

Urdu Bagh (اُردُو بَاغ - उर्दू बाग़) is a celebration of the Urdu language in its many facets. This podcast series showcases the work of Urdu legends, scholars, and activists. It also explores anecdotal history, celebrating the lives and works of Urdu’s literary giants, primarily through the memories of their family members, friends, historians, and activists.The series ‘Urdu Bagh’ is available on all major podcast platforms. Presented and produced by Pervaiz Alam for London-based Cine Ink, a hub for podcasts in Hindi and Urdu, the series is also accessible on major social media platforms, including Twitter, Facebook, Instagram, and LinkedIn. All Cine Ink podcasts can be found on its website, www.cineink.com. You can reach us at: post@cineink.com

Urdu Bagh (اُردُو بَاغ - उर्दू बाग़) is a celebration of the Urdu language in its many facets. This podcast series showcases the work of Urdu legends, scholars, and activists. It also explores anecdotal history, celebrating the lives and works of Urdu’s literary giants, primarily through the memories of their family members, friends, historians, and activists. The series ‘Urdu Bagh’ is available on all major podcast platforms. Presented and produced by Pervaiz Alam for London-based Cine Ink, a hub for podcasts in Hindi and Urdu, the series is also accessible on major social media platforms, including Twitter, Facebook, Instagram, and LinkedIn. All Cine Ink podcasts can be found on its website, <a href="http://www.cineink.com/" rel="noopener noreferrer">www.cineink.com</a>. You can reach us at: post@cineink.com

Urdu Bagh

The Urban Property Investor podcast with host Sam Saggers brings together the latest news, strategies and ideas to help grow your personal wealth from investing in real estate. With a major premise to help you join the 1% of people who achieve financial independence, Sam Saggers advocates ways to replace your income, invest in property and retire rich using trends that form part of the urban landscape.
 
The Urban Property Investor Podcast uncovers answers to the critical “what” “why” “where” and “how” of investment using behavioural economic insights into how everyone can prosper in the cities of tomorrow as investors of today. This podcast goes beyond investing in 2020 and tackles ways to bulletproof your investment plan by understanding influences on people, place and property.

The Urban Property Investor podcast with host Sam Saggers brings together the latest news, strategies and ideas to help grow your personal wealth from investing in real estate. With a major premise to help you join the 1% of people who achieve financial independence, Sam Saggers advocates ways to replace your income, invest in property and retire rich using trends that form part of the urban landscape. The Urban Property Investor Podcast uncovers answers to the critical “what” “why” “where” and “how” of investment using behavioural economic insights into how everyone can prosper in the cities of tomorrow as investors of today. This podcast goes beyond investing in 2020 and tackles ways to bulletproof your investment plan by understanding influences on people, place and property.

The Urban Property Investor

Parkinson's Disease: A Journey of Understanding, Hope, and Progress In the realm of neurodegenerative disorders, Parkinson's Disease (PD) stands as a formidable challenge, affecting millions of individuals worldwide. Named after Dr. James Parkinson, who first described the condition in 1817, PD is characterized by a constellation of motor symptoms, including tremors, stiffness, slowness of movement, and balance difficulties. These symptoms, which gradually rob individuals of their control over movement, arise from the loss of dopamine-producing neurons in the brain. As we delve into the complex world of PD, it becomes clear that this disease is far more than a simple movement disorder. It is a multifaceted condition that impacts not only the physical aspects of an individual's life but also their emotional, cognitive, and social well-being. The journey of understanding PD is one of unraveling the intricate interplay between the brain, the body, and the environment, and it is a journey that has been marked by significant advancements in recent years. At the heart of PD lies the pathophysiology of the disease, a complex web of cellular and molecular mechanisms that ultimately lead to the degeneration of dopaminergic neurons in the substantia nigra, a region of the midbrain. Dopamine, a neurotransmitter essential for regulating the brain's control of movement and coordination, is gradually depleted as these neurons die, giving rise to the hallmark motor symptoms of PD. But the story of PD's pathology does not end with the loss of dopamine. Researchers have discovered that the disease also involves the formation of abnormal aggregates of protein, primarily alpha-synuclein, within neurons. These aggregates, known as Lewy bodies, are a defining feature of PD, and their presence has sparked intense scientific interest. The exact causes of these protein aggregations and the subsequent neuronal death remain a mystery, with theories ranging from genetic mutations to environmental factors. As scientists work to unravel the complex etiology of PD, clinicians and patients alike are faced with the challenge of recognizing and addressing the early signs and symptoms of the disease. The onset of PD is typically insidious, with symptoms developing gradually over time. Early signs can be subtle, easily dismissed as the natural consequences of aging. Tremors, often starting in one hand and described as "pill-rolling," may be the first noticeable symptom. Bradykinesia, or slowness of movement, can make simple tasks like buttoning a shirt or tying shoelaces a time-consuming ordeal. Muscle rigidity, which can occur in any part of the body, may manifest as stiffness or a decreased range of motion. Impaired posture and balance, along with a loss of automatic movements like blinking or smiling, are also common early signs. But PD is not just a disease of movement. Non-motor symptoms, which often precede the onset of motor symptoms by several years, add another layer of complexity to the condition. Sleep disturbances, depression, anxiety, cognitive impairment, and autonomic dysfunction, such as constipation and blood pressure fluctuations, are all part of the PD experience. These non-motor symptoms can be just as debilitating as the motor symptoms, significantly impacting a person's quality of life. Diagnosing PD is a process of clinical acumen and exclusion, as there is no definitive laboratory test for the disease. Neurologists rely on their clinical examination skills and the patient's medical history to make a diagnosis, looking for the cardinal signs of PD and ruling out other conditions that may mimic its symptoms. Imaging studies, such as DAT-SPECT scans, which show reduced dopamine transporter activity in the brain, can support the diagnosis, but they are not definitive. Once a diagnosis of PD is made, the focus shifts to treatment and management. While there is currently no cure for PD, a range of treatments can help manage symptoms and improve quality of life. These treatments fall into three main categories: pharmacological, surgical, and non-pharmacological. Pharmacological treatments are the mainstay of PD management, with levodopa/carbidopa being the gold standard. Levodopa, a precursor to dopamine, is converted to dopamine in the brain, helping to replenish the depleted neurotransmitter. Carbidopa is added to prevent the premature conversion of levodopa to dopamine outside the brain, minimizing side effects. Other pharmacological options include dopamine agonists, which mimic the effects of dopamine; MAO-B inhibitors, which slow the breakdown of dopamine; COMT inhibitors, which prolong the action of levodopa; anticholinergics, which help reduce tremors and rigidity; and amantadine, which can provide symptomatic relief, particularly for levodopa-induced dyskinesias. Surgical treatments, such as deep brain stimulation (DBS), have emerged as a promising option for patients with advanced PD who respond poorly to medications. DBS involves implanting electrodes into specific areas of the brain and delivering electrical impulses to regulate abnormal brain activity. This technique has shown remarkable success in reducing motor symptoms and improving quality of life for many patients. Other surgical options, such as lesioning surgeries like pallidotomy and thalamotomy, are less common but may be considered in certain cases. Non-pharmacological treatments play a crucial role in the comprehensive management of PD. Physical therapy, with its focus on improving mobility, flexibility, and balance, can help patients maintain their physical function. Occupational therapy assists patients in managing daily activities and enhancing their quality of life through adaptive techniques and tools. Speech therapy addresses the speech and swallowing difficulties that are common in PD, helping patients maintain their ability to communicate and eat safely. Lifestyle modifications, including a healthy diet, stress management, and regular exercise, are also important components of PD management. In recent years, the landscape of PD research has been transformed by significant advancements in our understanding of the disease and the development of novel treatment approaches. Gene therapy, which involves delivering genes that can help restore dopamine production or protect neurons from degeneration, holds immense potential. Early clinical trials of AAV2-GDNF gene therapy have shown promise in providing neuroprotection and symptom relief. Stem cell therapy is another exciting area of research, with the goal of replacing lost dopaminergic neurons. Researchers are exploring the use of induced pluripotent stem cells (iPSCs) to generate dopamine-producing neurons for transplantation. Clinical trials are underway to assess the safety and efficacy of this approach, offering hope for a regenerative treatment for PD. Immunotherapy, which targets the abnormal aggregation of alpha-synuclein, is also showing promise. Vaccines and antibodies designed to clear or prevent the formation of these protein aggregates are being tested in clinical trials, with the potential to slow or halt the progression of PD. In addition to these cutting-edge therapies, new drug developments are expanding the treatment options for PD patients. NLY01, an experimental drug targeting neuroinflammation, has shown potential to slow disease progression in preclinical studies. Opicapone, a once-daily COMT inhibitor, enhances the effectiveness of levodopa and has been approved in some countries for managing motor fluctuations. Safinamide, a drug with dual mechanisms of action, provides additional symptom control for patients on levodopa therapy. Advances in DBS technology are also improving the precision and outcomes of this surgical treatment. Directional DBS leads allow for more targeted stimulation, reducing side effects and enhancing efficacy. Closed-loop DBS systems, which adjust stimulation in real-time based on brain activity, offer the promise of personalized and adaptive treatment. The role of gut microbiota in PD is an emerging area of research, with studies suggesting a link between gut microbial imbalances and the development and progression of the disease. Researchers are investigating whether modifying gut microbiota through diet, probiotics, or fecal transplants could offer therapeutic benefits for PD patients. Neuroprotective strategies, aimed at slowing or halting the progression of PD, are another active area of research. Molecules such as antioxidants, anti-inflammatory agents, and neurotrophic factors are being explored for their potential to protect neurons from degeneration. The calcium channel blocker isradipine, for example, has shown neuroprotective potential in preclinical studies and is currently being evaluated in clinical trials. Early diagnosis of PD is crucial for implementing neuroprotective strategies before significant neuronal loss occurs. Researchers are working to identify reliable biomarkers that can detect PD in its early stages, including imaging biomarkers, biochemical biomarkers in cerebrospinal fluid or blood, and genetic biomarkers. The role of lifestyle and environmental factors in PD development is also being actively investigated. Epidemiological studies have identified several factors that may influence PD risk, such as exposure to certain pesticides and herbicides, dietary habits, and exercise. Understanding the mechanisms by which these factors contribute to neurodegeneration could inform preventive strategies and targeted interventions. Clinical trials are the backbone of advancing PD treatment and research, providing valuable insights into the safety and efficacy of new therapies and refining existing ones. Patient involvement in these trials is essential for their success, and there are numerous ongoing trials invest

Parkinson's Disease: A Journey of Understanding, Hope, and Progress In the realm of neurodegenerative disorders, Parkinson's Disease (PD) stands as a formidable challenge, affecting millions of individuals worldwide. Named after Dr. James Parkinson, who first described the condition in 1817, PD is characterized by a constellation of motor symptoms, including tremors, stiffness, slowness of movement, and balance difficulties. These symptoms, which gradually rob individuals of their control over movement, arise from the loss of dopamine-producing neurons in the brain. As we delve into the complex world of PD, it becomes clear that this disease is far more than a simple movement disorder. It is a multifaceted condition that impacts not only the physical aspects of an individual's life but also their emotional, cognitive, and social well-being. The journey of understanding PD is one of unraveling the intricate interplay between the brain, the body, and the environment, and it is a journey that has been marked by significant advancements in recent years. At the heart of PD lies the pathophysiology of the disease, a complex web of cellular and molecular mechanisms that ultimately lead to the degeneration of dopaminergic neurons in the substantia nigra, a region of the midbrain. Dopamine, a neurotransmitter essential for regulating the brain's control of movement and coordination, is gradually depleted as these neurons die, giving rise to the hallmark motor symptoms of PD. But the story of PD's pathology does not end with the loss of dopamine. Researchers have discovered that the disease also involves the formation of abnormal aggregates of protein, primarily alpha-synuclein, within neurons. These aggregates, known as Lewy bodies, are a defining feature of PD, and their presence has sparked intense scientific interest. The exact causes of these protein aggregations and the subsequent neuronal death remain a mystery, with theories ranging from genetic mutations to environmental factors. As scientists work to unravel the complex etiology of PD, clinicians and patients alike are faced with the challenge of recognizing and addressing the early signs and symptoms of the disease. The onset of PD is typically insidious, with symptoms developing gradually over time. Early signs can be subtle, easily dismissed as the natural consequences of aging. Tremors, often starting in one hand and described as "pill-rolling," may be the first noticeable symptom. Bradykinesia, or slowness of movement, can make simple tasks like buttoning a shirt or tying shoelaces a time-consuming ordeal. Muscle rigidity, which can occur in any part of the body, may manifest as stiffness or a decreased range of motion. Impaired posture and balance, along with a loss of automatic movements like blinking or smiling, are also common early signs. But PD is not just a disease of movement. Non-motor symptoms, which often precede the onset of motor symptoms by several years, add another layer of complexity to the condition. Sleep disturbances, depression, anxiety, cognitive impairment, and autonomic dysfunction, such as constipation and blood pressure fluctuations, are all part of the PD experience. These non-motor symptoms can be just as debilitating as the motor symptoms, significantly impacting a person's quality of life. Diagnosing PD is a process of clinical acumen and exclusion, as there is no definitive laboratory test for the disease. Neurologists rely on their clinical examination skills and the patient's medical history to make a diagnosis, looking for the cardinal signs of PD and ruling out other conditions that may mimic its symptoms. Imaging studies, such as DAT-SPECT scans, which show reduced dopamine transporter activity in the brain, can support the diagnosis, but they are not definitive. Once a diagnosis of PD is made, the focus shifts to treatment and management. While there is currently no cure for PD, a range of treatments can help manage symptoms and improve quality of life. These treatments fall into three main categories: pharmacological, surgical, and non-pharmacological. Pharmacological treatments are the mainstay of PD management, with levodopa/carbidopa being the gold standard. Levodopa, a precursor to dopamine, is converted to dopamine in the brain, helping to replenish the depleted neurotransmitter. Carbidopa is added to prevent the premature conversion of levodopa to dopamine outside the brain, minimizing side effects. Other pharmacological options include dopamine agonists, which mimic the effects of dopamine; MAO-B inhibitors, which slow the breakdown of dopamine; COMT inhibitors, which prolong the action of levodopa; anticholinergics, which help reduce tremors and rigidity; and amantadine, which can provide symptomatic relief, particularly for levodopa-induced dyskinesias. Surgical treatments, such as deep brain stimulation (DBS), have emerged as a promising option for patients with advanced PD who respond poorly to medications. DBS involves implanting electrodes into specific areas of the brain and delivering electrical impulses to regulate abnormal brain activity. This technique has shown remarkable success in reducing motor symptoms and improving quality of life for many patients. Other surgical options, such as lesioning surgeries like pallidotomy and thalamotomy, are less common but may be considered in certain cases. Non-pharmacological treatments play a crucial role in the comprehensive management of PD. Physical therapy, with its focus on improving mobility, flexibility, and balance, can help patients maintain their physical function. Occupational therapy assists patients in managing daily activities and enhancing their quality of life through adaptive techniques and tools. Speech therapy addresses the speech and swallowing difficulties that are common in PD, helping patients maintain their ability to communicate and eat safely. Lifestyle modifications, including a healthy diet, stress management, and regular exercise, are also important components of PD management. In recent years, the landscape of PD research has been transformed by significant advancements in our understanding of the disease and the development of novel treatment approaches. Gene therapy, which involves delivering genes that can help restore dopamine production or protect neurons from degeneration, holds immense potential. Early clinical trials of AAV2-GDNF gene therapy have shown promise in providing neuroprotection and symptom relief. Stem cell therapy is another exciting area of research, with the goal of replacing lost dopaminergic neurons. Researchers are exploring the use of induced pluripotent stem cells (iPSCs) to generate dopamine-producing neurons for transplantation. Clinical trials are underway to assess the safety and efficacy of this approach, offering hope for a regenerative treatment for PD. Immunotherapy, which targets the abnormal aggregation of alpha-synuclein, is also showing promise. Vaccines and antibodies designed to clear or prevent the formation of these protein aggregates are being tested in clinical trials, with the potential to slow or halt the progression of PD. In addition to these cutting-edge therapies, new drug developments are expanding the treatment options for PD patients. NLY01, an experimental drug targeting neuroinflammation, has shown potential to slow disease progression in preclinical studies. Opicapone, a once-daily COMT inhibitor, enhances the effectiveness of levodopa and has been approved in some countries for managing motor fluctuations. Safinamide, a drug with dual mechanisms of action, provides additional symptom control for patients on levodopa therapy. Advances in DBS technology are also improving the precision and outcomes of this surgical treatment. Directional DBS leads allow for more targeted stimulation, reducing side effects and enhancing efficacy. Closed-loop DBS systems, which adjust stimulation in real-time based on brain activity, offer the promise of personalized and adaptive treatment. The role of gut microbiota in PD is an emerging area of research, with studies suggesting a link between gut microbial imbalances and the development and progression of the disease. Researchers are investigating whether modifying gut microbiota through diet, probiotics, or fecal transplants could offer therapeutic benefits for PD patients. Neuroprotective strategies, aimed at slowing or halting the progression of PD, are another active area of research. Molecules such as antioxidants, anti-inflammatory agents, and neurotrophic factors are being explored for their potential to protect neurons from degeneration. The calcium channel blocker isradipine, for example, has shown neuroprotective potential in preclinical studies and is currently being evaluated in clinical trials. Early diagnosis of PD is crucial for implementing neuroprotective strategies before significant neuronal loss occurs. Researchers are working to identify reliable biomarkers that can detect PD in its early stages, including imaging biomarkers, biochemical biomarkers in cerebrospinal fluid or blood, and genetic biomarkers. The role of lifestyle and environmental factors in PD development is also being actively investigated. Epidemiological studies have identified several factors that may influence PD risk, such as exposure to certain pesticides and herbicides, dietary habits, and exercise. Understanding the mechanisms by which these factors contribute to neurodegeneration could inform preventive strategies and targeted interventions. Clinical trials are the backbone of advancing PD treatment and research, providing valuable insights into the safety and efficacy of new therapies and refining existing ones. Patient involvement in these trials is essential for their success, and there are numerous ongoing trials invest

Parkinson's Disease: A Journey of Understanding, Hope, and Progress In the realm of neurodegenerative disorders, Parkinson's Disease (PD) stands as a formidable challenge, affecting millions of individuals worldwide. Named after Dr. James Parkinson, who first described the condition in 1817, PD is characterized by a constellation of motor symptoms, including tremors, stiffness, slowness of movement, and balance difficulties. These symptoms, which gradually rob individuals of their control over movement, arise from the loss of dopamine-producing neurons in the brain. As we delve into the complex world of PD, it becomes clear that this disease is far more than a simple movement disorder. It is a multifaceted condition that impacts not only the physical aspects of an individual's life but also their emotional, cognitive, and social well-being. The journey of understanding PD is one of unraveling the intricate interplay between the brain, the body, and the environment, and it is a journey that has been marked by significant advancements in recent years. At the heart of PD lies the pathophysiology of the disease, a complex web of cellular and molecular mechanisms that ultimately lead to the degeneration of dopaminergic neurons in the substantia nigra, a region of the midbrain. Dopamine, a neurotransmitter essential for regulating the brain's control of movement and coordination, is gradually depleted as these neurons die, giving rise to the hallmark motor symptoms of PD. But the story of PD's pathology does not end with the loss of dopamine. Researchers have discovered that the disease also involves the formation of abnormal aggregates of protein, primarily alpha-synuclein, within neurons. These aggregates, known as Lewy bodies, are a defining feature of PD, and their presence has sparked intense scientific interest. The exact causes of these protein aggregations and the subsequent neuronal death remain a mystery, with theories ranging from genetic mutations to environmental factors. As scientists work to unravel the complex etiology of PD, clinicians and patients alike are faced with the challenge of recognizing and addressing the early signs and symptoms of the disease. The onset of PD is typically insidious, with symptoms developing gradually over time. Early signs can be subtle, easily dismissed as the natural consequences of aging. Tremors, often starting in one hand and described as "pill-rolling," may be the first noticeable symptom. Bradykinesia, or slowness of movement, can make simple tasks like buttoning a shirt or tying shoelaces a time-consuming ordeal. Muscle rigidity, which can occur in any part of the body, may manifest as stiffness or a decreased range of motion. Impaired posture and balance, along with a loss of automatic movements like blinking or smiling, are also common early signs. But PD is not just a disease of movement. Non-motor symptoms, which often precede the onset of motor symptoms by several years, add another layer of complexity to the condition. Sleep disturbances, depression, anxiety, cognitive impairment, and autonomic dysfunction, such as constipation and blood pressure fluctuations, are all part of the PD experience. These non-motor symptoms can be just as debilitating as the motor symptoms, significantly impacting a person's quality of life. Diagnosing PD is a process of clinical acumen and exclusion, as there is no definitive laboratory test for the disease. Neurologists rely on their clinical examination skills and the patient's medical history to make a diagnosis, looking for the cardinal signs of PD and ruling out other conditions that may mimic its symptoms. Imaging studies, such as DAT-SPECT scans, which show reduced dopamine transporter activity in the brain, can support the diagnosis, but they are not definitive. Once a diagnosis of PD is made, the focus shifts to treatment and management. While there is currently no cure for PD, a range of treatments can help manage symptoms and improve quality of life. These treatments fall into three main categories: pharmacological, surgical, and non-pharmacological. Pharmacological treatments are the mainstay of PD management, with levodopa/carbidopa being the gold standard. Levodopa, a precursor to dopamine, is converted to dopamine in the brain, helping to replenish the depleted neurotransmitter. Carbidopa is added to prevent the premature conversion of levodopa to dopamine outside the brain, minimizing side effects. Other pharmacological options include dopamine agonists, which mimic the effects of dopamine; MAO-B inhibitors, which slow the breakdown of dopamine; COMT inhibitors, which prolong the action of levodopa; anticholinergics, which help reduce tremors and rigidity; and amantadine, which can provide symptomatic relief, particularly for levodopa-induced dyskinesias. Surgical treatments, such as deep brain stimulation (DBS), have emerged as a promising option for patients with advanced PD who respond poorly to medications. DBS involves implanting electrodes into specific areas of the brain and delivering electrical impulses to regulate abnormal brain activity. This technique has shown remarkable success in reducing motor symptoms and improving quality of life for many patients. Other surgical options, such as lesioning surgeries like pallidotomy and thalamotomy, are less common but may be considered in certain cases. Non-pharmacological treatments play a crucial role in the comprehensive management of PD. Physical therapy, with its focus on improving mobility, flexibility, and balance, can help patients maintain their physical function. Occupational therapy assists patients in managing daily activities and enhancing their quality of life through adaptive techniques and tools. Speech therapy addresses the speech and swallowing difficulties that are common in PD, helping patients maintain their ability to communicate and eat safely. Lifestyle modifications, including a healthy diet, stress management, and regular exercise, are also important components of PD management. In recent years, the landscape of PD research has been transformed by significant advancements in our understanding of the disease and the development of novel treatment approaches. Gene therapy, which involves delivering genes that can help restore dopamine production or protect neurons from degeneration, holds immense potential. Early clinical trials of AAV2-GDNF gene therapy have shown promise in providing neuroprotection and symptom relief. Stem cell therapy is another exciting area of research, with the goal of replacing lost dopaminergic neurons. Researchers are exploring the use of induced pluripotent stem cells (iPSCs) to generate dopamine-producing neurons for transplantation. Clinical trials are underway to assess the safety and efficacy of this approach, offering hope for a regenerative treatment for PD. Immunotherapy, which targets the abnormal aggregation of alpha-synuclein, is also showing promise. Vaccines and antibodies designed to clear or prevent the formation of these protein aggregates are being tested in clinical trials, with the potential to slow or halt the progression of PD. In addition to these cutting-edge therapies, new drug developments are expanding the treatment options for PD patients. NLY01, an experimental drug targeting neuroinflammation, has shown potential to slow disease progression in preclinical studies. Opicapone, a once-daily COMT inhibitor, enhances the effectiveness of levodopa and has been approved in some countries for managing motor fluctuations. Safinamide, a drug with dual mechanisms of action, provides additional symptom control for patients on levodopa therapy. Advances in DBS technology are also improving the precision and outcomes of this surgical treatment. Directional DBS leads allow for more targeted stimulation, reducing side effects and enhancing efficacy. Closed-loop DBS systems, which adjust stimulation in real-time based on brain activity, offer the promise of personalized and adaptive treatment. The role of gut microbiota in PD is an emerging area of research, with studies suggesting a link between gut microbial imbalances and the development and progression of the disease. Researchers are investigating whether modifying gut microbiota through diet, probiotics, or fecal transplants could offer therapeutic benefits for PD patients. Neuroprotective strategies, aimed at slowing or halting the progression of PD, are another active area of research. Molecules such as antioxidants, anti-inflammatory agents, and neurotrophic factors are being explored for their potential to protect neurons from degeneration. The calcium channel blocker isradipine, for example, has shown neuroprotective potential in preclinical studies and is currently being evaluated in clinical trials. Early diagnosis of PD is crucial for implementing neuroprotective strategies before significant neuronal loss occurs. Researchers are working to identify reliable biomarkers that can detect PD in its early stages, including imaging biomarkers, biochemical biomarkers in cerebrospinal fluid or blood, and genetic biomarkers. The role of lifestyle and environmental factors in PD development is also being actively investigated. Epidemiological studies have identified several factors that may influence PD risk, such as exposure to certain pesticides and herbicides, dietary habits, and exercise. Understanding the mechanisms by which these factors contribute to neurodegeneration could inform preventive strategies and targeted interventions. Clinical trials are the backbone of advancing PD treatment and research, providing valuable insights into the safety and efficacy of new therapies and refining existing ones. Patient involvement in these trials is essential for their success, and there are numerous ongoing trials invest

Parkinson’s Disease:

Voor alles is een eerste keer. Maar hoe werkt dat eigenlijk: Naakt kamperen, airfryen, waarzeggers en carrièreswitches?
In deze eclectische chatcast neemt Mignon Nusteling jou, samen met haar man Sebastian, vriend én vijand mee naar hun eerste ervaringen. Ze vertellen direct hoe jij het beter kunt doen. Van belastingaangifte tot limbodansen op de campingdisco: Na het luisteren van deze podcast durf jij alles. Of je dat moet willen, is een tweede.
Wilt u met deze podcast en/of een andere podcast van ILVY Network samenwerken? Mail ons dan op management@ilvy.com met uw concrete vraag en een indicatie/range van uw beschikbare budget. Wij reageren doorgaans binnen 24 met een concreet voorstel en en wie-weet kunnen we een mooie samenwerking creëren waar de luisteraar, u en wij bij gebaat zijn!
http://eerstedingen.nl
'Alle Eerste Dingen' heeft ca. 35.000 luistermomenten per maand en is een productie van ILVY Network ©️ 2022-2025 ILVY B.V. https://ilvy.com

Voor alles is een eerste keer. Maar hoe werkt dat eigenlijk: Naakt kamperen, airfryen, waarzeggers en carrièreswitches? In deze eclectische chatcast neemt Mignon Nusteling jou, samen met haar man Sebastian, vriend én vijand mee naar hun eerste ervaringen. Ze vertellen direct hoe jij het beter kunt doen. Van belastingaangifte tot limbodansen op de campingdisco: Na het luisteren van deze podcast durf jij alles. Of je dat moet willen, is een tweede. Wilt u met deze podcast en/of een andere podcast van ILVY Network samenwerken? Mail ons dan op management@ilvy.com met uw concrete vraag en een indicatie/range van uw beschikbare budget. Wij reageren doorgaans binnen 24 met een concreet voorstel en en wie-weet kunnen we een mooie samenwerking creëren waar de luisteraar, u en wij bij gebaat zijn! http://eerstedingen.nl 'Alle Eerste Dingen' heeft ca. 35.000 luistermomenten per maand en is een productie van ILVY Network ©️ 2022-2025 ILVY B.V. https://ilvy.com

Alle Eerste Dingen

My vision for this podcast is to inspire individuals to exceed their own expectations and unlock their true potential, providing them with the clarity and purpose to lead more fulfilling lives. To contact me, you can reach out here at dave@thelastpodcast.info
Website - http://thelastpodcast.info/ 

Publishing Days: Monday, Wednesday, and Poetry Friday.
You don't want to miss listening on Fridays if you enjoy poetry.
If you have a poem you want to recite, 
reach out to me at dave@thelastpodcast.info or thelastpodcast443@gmail.com.


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We want to hear from you.

YouTube: https://www.youtube.com/@TheLastPodcast-cs5jx

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Website:  http://thelastpodcast.info/

My vision for this podcast is to inspire individuals to exceed their own expectations and unlock their true potential, providing them with the clarity and purpose to lead more fulfilling lives. To contact me, you can reach out here at dave@thelastpodcast.info Website - http://thelastpodcast.info/ Publishing Days: Monday, Wednesday, and Poetry Friday. You don't want to miss listening on Fridays if you enjoy poetry. If you have a poem you want to recite, reach out to me at dave@thelastpodcast.info or thelastpodcast443@gmail.com. Do you have an inspiring story you want to share with our listeners? We want to hear from you. YouTube: https://www.youtube.com/@TheLastPodcast-cs5jx Get a free quote for life insurance. https://finalexpenseplan.info/ Website: http://thelastpodcast.info/

My vision for this podcast is to inspire individuals to exceed their own expectations and unlock their true potential, providing them with the clarity and purpose to lead more fulfilling lives. To contact me, you can reach out here at dave@thelastpodcast.info
Website - http://thelastpodcast.info/ 

Publishing Days: Monday, Wednesday, and Poetry Friday.
You don't want to miss listening on Fridays if you enjoy poetry.
If you have a poem you want to recite, 
reach out to me at dave@thelastpodcast.info or thelastpodcast443@gmail.com.


Do you have an inspiring story you want to share with our listeners?
We want to hear from you.

YouTube: https://www.youtube.com/@TheLastPodcast-cs5jx

Get a free quote for life insurance.
https://finalexpenseplan.info/

Website:&nbsp; http://thelastpodcast.info/

The Last Podcast

The VetMed Weekly Huddle is provided by Veterinary Growth Partners to help support you and your team to have a great start to their workday. Topics range from Emotional Intelligence to Team Dynamics.

The VetMed Weekly Huddle

Exploring the futurology of the summer camp industry.

Exploring the futurology of the summer camp industry.

Camp Ahead

Have you ever thought about what life looks like from the lenses of winners? True winners who balance the ups and downs of life through a different pair of lenses

Have you ever thought about what life looks like from the lenses of winners? True winners who balance the ups and downs of life through a different pair of lenses

Have you ever thought about what life looks like from the lenses of winners? True winners who balance the ups and downs of life through a different&nbsp;pair&nbsp;of&nbsp;lenses

The Winners Seat Podcast

英語と文化とアメリカの話を題材に英語を学ぶポッドキャストです世界中の人と対等に話せる英語を身につけましょう！：）

英語と文化とアメリカの話を題材に英語を学ぶポッドキャストです 世界中の人と対等に話せる英語を身につけましょう！：）

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Alle Eerste Dingen

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