The Psychedelic Podcast

Sterling Cooley - Xenon as Medicine: Exploring the Psychedelic Noble Gas


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In this episode of The Psychedelic Podcast, Paul F. Austin welcomes researcher and entrepreneur Sterling Cooley to explore xenon—the noble gas with surprising psychedelic-like effects. Sterling shares how his own health crisis led him from nitrous oxide to xenon, and why he believes gaseous anesthetics open a unique window into consciousness.

Find full show notes and links here: https://thethirdwave.co/podcast/episode-322/?ref=278

Sterling connects xenon to microtubule research (Orch OR), contrasts it with ketamine and nitrous, and discusses harm-reduction considerations, trip reports, and integration. The discussion bridges Sterling’s personal journey with emerging scientific theories, offering a thoughtful look at xenon’s potential role in consciousness and healing.

Guest Bio Sterling Cooley is a researcher and biotech entrepreneur working in ultrasound neuromodulation and noninvasive vagus nerve stimulation. Over the past decade, he has collaborated with Dr. Stuart Hameroff on microtubules, quantum consciousness, and novel anesthetics. Sterling is focused on xenon, a noble gas with both anesthetic and psychedelic-like properties. Through his community at Skool.com/Ultra, he supports safe, informed exploration of xenon’s therapeutic and consciousness-expanding potential.

Highlights:

  • What xenon is and why it fascinates researchers
  • Sterling’s personal health journey with gaseous anesthetics
  • Microtubules, Orch OR, and models of consciousness
  • Xenon vs. ketamine vs. nitrous: similarities and differences
  • Harm-reduction guidance for gaseous psychedelics
  • Visionary and higher-self experiences on xenon
  • Potential applications for pain and PTSD
  • Why microtubules may bridge mind, matter, and ideals

Episode Links:

  • Ultra Skool

  • Skool.com/Ultra (Sterling’s community and xenon classroom)

  • Sterling on X

  • Purchase Xenon Gas (USA)

Episode Sponsors:

  • The Practitioner Certification Program by Third Wave’s Psychedelic Coaching Institute.
  • Golden Rule Mushrooms - Get a lifetime discount of 10% with code THIRDWAVE at checkout

Disclaimer: Third Wave’s content is for educational and informational purposes only. We do not provide medical or legal advice, diagnosis, or treatment. Always consult a qualified healthcare professional before making decisions about your mental or physical health. Nothing here is intended as encouragement to use any substance, and we do not advocate for illegal activity.

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