One of America's best-known & best-loved physicians, Andrew Weil, joins Chris to chat about alternative medicine, the healing potential of altered states, and his pivotal role in changing modern medical history.

Chris drops in on his pal, Dr. Stanley Krippner, one of the world's leading experts on telepathy, shamanism, and consciousness. Their conversation ranges from Brazilian ayahuasca ceremonies to the Grateful Dead's penises-and everything in between.

The man who got Chris into podcasting, comedian Duncan Trussell, joins Tangentially Speaking! Stand up comedy is compared to geology. Hecklers are dissected. The conversation is a fractal and wild, Chris and Duncan attempt to bring order it.

This week, Christopher joins Tao Ruspoli a flamenco guitarist, Italian prince, and accomplished film-maker in Ruspoli's camper van to talk about drugs, what it's like to work with Oliver Stone, and Roman Polanski's match-making skills.

Dominatrix Kaila Yi presents a gripping interview on her sexuality and work then reveals some intimate if not painful details of her life.

Author of The Game, Neil Strauss joins Dr. Chris Ryan on the premiere episode of his podcast. They talk books and critique each others work. Subscribe on iTunes!