Nicotine, a naturally occurring alkaloid found in tobacco plants, is a substance known to most people for its association with cigarettes, addiction, and the health risks of smoking. However, nicotine on its own, when isolated from the harmful chemicals found in tobacco smoke, may offer some surprising health benefits. Recent research has begun to uncover potential therapeutic uses for nicotine, particularly in cognitive enhancement and neuroprotection as well as metabolism enhancement and appetite suppression. In this segment, Jillian explores the health benefits of nicotine, looking at what science says about its positive effects while keeping in mind the potential risks.