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"The reality is that the metabolic defects of the brain that presage to the development of Alzheimer's disease begin 20 to 30 years prior to the clinical manifestations." -Dr. David Perlmutter

In this groundbreaking episode, renowned neurologist Dr. David Perlmutter shatters conventional wisdom about Alzheimer's disease, revealing why the current focus on beta-amyloid proteins might be missing the mark entirely. With decades of clinical experience and research, Dr. Perlmutter explains how metabolic health - not genetics - is the primary driver behind the staggering rise in Alzheimer's cases worldwide. He breaks down complex concepts into digestible insights, comparing the brain's energy needs to a car engine and revealing the fascinating fact that a single brain cell contains up to a thousand mitochondria, our cellular powerhouses.

Drawing from his extensive research, Dr. Perlmutter emphasizes that brain degeneration begins decades before symptoms appear, making early intervention crucial. He challenges the reactive approach of modern medicine, advocating instead for proactive metabolic health management. The conversation delves deep into how our lifestyle choices today impact our cognitive function tomorrow, offering hope through the understanding that many risk factors for Alzheimer's are within our control. Through captivating analogies and clear scientific explanations, Dr. Perlmutter provides a revolutionary framework for understanding and protecting our brain health, long before memory issues arise.

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Alex Hormozi, Entrepreneur and Best-selling Author shares the mindset and steps you need to take to become a millionaire.

Check out the full episode: http://www.lewishowes.com/1324

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"The hardest thing I've ever done was look in the mirror and tell myself I was sorry - sorry for what I've got myself into, the choices that I made." - Eric Thomas

In a raw and revealing conversation, Eric Thomas opens up about the pivotal moment that transformed his life from living in abandoned buildings as a homeless high school dropout to becoming one of the most influential voices in personal development. ET shares the painful reality of discovering family secrets at age 12 and his subsequent pattern of running away from conflicts, highlighting how his victim mindset kept him trapped in a cycle of blame and self-sabotage. His story demonstrates the profound impact of taking personal responsibility, even in the face of legitimate childhood trauma and difficult circumstances.

The conversation delves deep into Thomas's powerful realization that he was the common denominator in his life circumstances, leading to a transformative moment of self-reflection and accountability. Rather than continuing to blame his mother's teenage pregnancy, his absent biological father, or his challenging upbringing in Detroit, ET describes the liberating yet difficult process of acknowledging his role in his life's direction. This honest examination of his past reveals how shifting from external blame to internal responsibility became the foundation for his extraordinary journey of personal growth and professional success.

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"I will come to you until you buy or you die." - Ryan Serhant

Growing up in a large family with three sisters and two brothers, Ryan Serhant spent years searching for his true calling. He tried every sport, took countless classes, and even pursued acting, but nothing clicked as his definitive path. That all changed when he accidentally got his real estate license to pay rent during the 2008 financial crisis. Unlike acting, where rejection felt deeply personal, Ryan approached real estate with a volume-based mindset, making a conscious decision that no one could outwork him. He committed to waking up earlier and going to bed later than anyone else, refusing to let modern discussions about work-life balance deter him from his mission.

What sets Ryan apart isn't just his work ethic – it's his unshakeable persistence. After his first big commission check of $24,000, which covered a year's rent, he immediately set his sights on bigger goals. This same determination led him to pitch show concepts to Bravo nearly 30 times before they finally gave him a chance with "Sell It Like Serhant." Ryan's philosophy is simple yet powerful: work so hard that you make luck easy to find. Through consistent effort and refusing to take no for an answer, he transformed from a struggling actor into one of real estate's most recognizable faces, proving that sometimes your greatest strength isn't being the most connected or talented – it's being the one who never gives up.

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Order a copy of my new book The Greatness Mindset today!

Robert Greene, Best-selling Author shares the process to changing your mindset around your flaws and how to use them to your advantage.

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"By the time somebody else has thought about an idea, gone to investment committee, pondered it, I've already started, made three mistakes, and found a better way." - Codie Sanchez

From a $37,000 salary to building multiple successful businesses, Codie Sanchez's journey is a masterclass in breaking free from corporate constraints. In this raw and energetic conversation, she shares the pivotal moment when a boss's rejection of her business idea became the catalyst for her entrepreneurial rise. With remarkable candor, Codie reveals how being labeled as someone who would "leave dead bodies behind" in the corporate world led her to embrace her ambitious nature and chart her own path to financial freedom. Her unconventional wisdom challenges the traditional narrative about career loyalty, encouraging listeners to become the architects of their own fate.

Drawing from her extensive experience, Codie breaks down the three essential elements of building wealth: mindset, zero-to-one breakthrough, and what she calls "contagion" - the art of making money magnetic. She dispels the myth that success requires superior intelligence or pre-existing wealth, instead emphasizing the power of speed and decisive action. With refreshing honesty, Codie addresses the role of emotions in business building, acknowledging that drive can come from various sources - including constructive anger - challenging the typical "love-only" approach to entrepreneurship. Listen to the full episode to discover Codie's counterintuitive strategies for breaking through wealth barriers and seizing the unprecedented opportunities in today's business landscape.

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Phil Heath, 7x Mr. Olympia Champion shares how to overcome failure in order to reach a new level of success.

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"If you're just thinking this with the frontal part of your mind, but you really know deep down that money is evil, money is bad... you're never going to actually achieve the outcome that you want." - Jaspreet Singh

Financial expert Jaspreet Singh delves deep into the psychology of wealth, revealing how our earliest money beliefs shape our financial destiny. With compelling insight, he explains why simply trying to think positive thoughts about money isn't enough – we must first address the deeply ingrained subconscious beliefs that silently sabotage our financial success. Singh illuminates how childhood messages about money being "evil" or "not for people like us" create invisible barriers that persist into adulthood, perpetuating cycles of generational poverty.

The conversation takes a powerful turn as Singh challenges listeners to examine their relationship with wealth beyond surface-level affirmations. He dismantles common misconceptions about money's scarcity and reveals how our judgments of wealthy people often mask our own financial insecurities. Through practical wisdom and frank discussion, Singh demonstrates how money acts as a tool for freedom and choice, emphasizing that true financial transformation begins with healing our money mindset and breaking free from inherited limiting beliefs.

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Jillian Turecki, Relationship Expert and Podcast Host shares the different ways we can thrive in relationships.

Check out the full episode: http://www.lewishowes.com/1355

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"When I went to medical school, there was nothing called type 2 diabetes... Now kids as young as 2 or 3 years old are getting type 2 diabetes." - Dr. Mark Hyman

Dr. Mark Hyman delivers a sobering examination of America's deteriorating food system and its catastrophic impact on public health. From the post-WWII industrialization of agriculture to today's epidemic of chronic diseases, he reveals how our food production methods have led to environmental destruction, depleted soil quality, and devastating health consequences. His stark comparison of health statistics from the 1970s to today's 42% obesity rate illuminates the urgent crisis we face, while his expertise as a physician adds weight to the alarming rise in type 2 diabetes, heart disease, and childhood illnesses.

The conversation takes a deep dive into the staggering statistics of chronic illness in America, where 6 out of 10 adults currently suffer from at least one chronic disease. Dr. Hyman connects the dots between our industrialized food system, environmental toxins, and the exponential rise in conditions like autoimmune diseases, mental illness, and cancer in young people. Through compelling examples and clear explanations, he demonstrates how our massive spending on healthcare and pharmaceuticals isn't addressing the root causes of these diseases, challenging listeners to reconsider their relationship with food and its impact on their health.

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