Wes, Eneasz, and David discuss the news from the last two weeks from a rationalist perspective

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News discussed:

Hypnosis, LSD, and the Unabomber

Harvard and the Making of the Unabomber

SCOTUS granted stay in mifepristone case

Alito and Thomas dissented

Clarence Thomas’s billionaire friend also bought his property at an above-market price and let Thomas’ mother live there for free

Fox settled the Dominion lawsuit for $787 million

And Tucker Carlson is out!

Florida enacts six-week abortion ban

Florida allows death penalty by 8-4 jury vote

German Green party decides that giving the lignite coal industry a massive boost by shutting down their nuclear power plants

Congress failed to extend a key tax provision last year allowing companies to fully expense research & development costs in the year incurred. See SSBalliance.org

North Dakota banned approval voting

Update: veto override failed!!

Russia widely published intentions to move nukes to Belarus, but doesn’t seem to have actually done it. 

Lot of discussion of Mackaroon being soft on China, but Tyler Cowen-endorsed Twitter thread says this is a misinterpretation.

Counterpoint

Some protests in Sundan turned violent. President Bashir declared state of emergency in Feb 2019, dissolved the govt

They did not hand over power. 

“lil mohammad” Hemedti

Buhan and Hemedit both think the old govt sucks, they should rule the new govt, and they’re gonna fight about it

Countries are pulling out all their diplomats/peeps

NIH blows $1B trying to make Long COVID a thing

Happy News!

Ghana has approved a malaria vaccine for deployment

Reforms signed three years ago in Michigan took effect last week, with nearly 850,000 residents seeing at least one conviction automatically set aside

Scientists have discovered that intersecting gravity waves shortly after the big bang generated the universe’s first photons

Hubble saw a supermassive black hole three times the diameter of our whole galaxy, speeding through the universe. 

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Bonus episode featuring an interview with Jorge, the so-called “mayor of Próspera.”

Wes, Eneasz, and David keep the rationalist community informed about what’s going on outside of the rationalist community

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News discussed:

DEA ruins telemedicine

Trump is already selling mug shots

The liberals won the Wisconsin Supreme Court seat

Senate voted to repeal 2002 AUMF

McCarthy says House will probably pass it, but it has to go through committee

Nationwide injunction on abortion pills, but also the opposite of that

Biggest intelligence leak since Snowden

First appeared on a tiny meme-Discord 5 weeks ago

Reboot/NoFap appears to make followers *worse*

Doocy asks about AI Doom at White House press briefing

LLMs can greatly compress prompts for future self-decoding (but lossy)

Chatbot convinces Belgian to commit suicide

AI village of 25 NPCs created. Amazing results

Happy News!

New Nuclear plant plugged into the grid

Drs Feng Zhang and Joe Kreitz created a molecular delivery system that can deliver proteins only to specific types of cells

Professor Gilad Yossifon created microrobots that can navigate between cells, and identify and capture individual cells

Now CRISPR RNA is delivered to the mouse lung by inhalation using improved lipid nanoparticles

Paves the way for therapeutic CRISPR applications in the lung, including possibly cystic fibrosis!

Some Coastal Salt Marshes Are Keeping Up With Sea Level Rise

FDA stops preventing people from buying a life-saving drug!

Blast your heart with your own stem cells to reduce inflammation, risk of heart attack and stroke!

Utah and California Snowpacks Break All Previous Record. “cautiously optimistic” “Drought is expected to improve further or go away completely across much of California.”.

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Wes, Eneasz, and David discuss the news from the last two weeks from a rationalist perspective

Support us on Substack!

News discussed:

Credit Suisse collapsed and bought by UBS

RESTRICT Act seems like a big Executive power grab

Utah is building a registry of all residents that use social media. RIP David

Also requires parental consent for anyone under 18 to be on, and gives parents full access to children’s accounts 

Biden vetoed anti woke capital resolution

New executive order on guns

NRA says it’s announcing “a general principle that federal agencies should use whatever authorities they have to make life more difficult for gun owners or the businesses that serve them”

Trump threatened “potential death and destruction” if he’s criminally charged

ARC tested GPT4 capabilities, including prompting it to try to break out and replicate.

ChatGPT Plugins let it browse the web, do stuff for you

Text-only GPT-4 learned what things look like and can draw them 

Meta made a model 95% as good as ChatGPT, that is small enough to run on your phone

Eternal Children

Llamas with Hats!

Happy News!

GPT4 saved a dog’s life by accurately diagnosing it after being given symptoms

FTC voted 3-1 to introduce "click to cancel," to easy subscription cancellations.

stretchable bandage that accelerates healing by delivering electrotherapy directly to the wound speeds healing by 30%. the components that interface with the wound are entirely resorbable

Lies about Chris Avelone dismissed with prejudice in libel suit, awarded over $1M, and the perps have made public renunciations of their lies.

retinitis pigmentosa affects 1 in 4000, causes blindness, cured by CRISPR

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Wes, Eneasz, and David discuss the news from the last two weeks from a rationalist perspective

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News discussed:

S**t is going down in Israel

Big protests over Netanyahu’s proposed judicial reforms

New proposals would give political appointees a majority

Elite fighter squadron is boycotting training

Silicon Valley Bank is insolvent

Jacob Falkovich blames the government

Bank run stopped by new Fed policy 

the Bank Term Funding Program

Anthropic Shadow? 

“this is what it would look like if you wanted to stifle innovative sectors”

In Nebraska a mom & daughter will stand trial for abortion

The American Association of Pediatric released new guidelines for childhood obesity

Eating disorder experts are not happy

FTC is going after Musk

FTC is unhappy about “twitter files” exposing this, demands list of journalists from twitter, issues fines

FTC commissioner resigns, cites FTC Chairman’s “disregard for the rule of law and due process,” and “abuses of government power,” 

Partisan rift forming around FTC? Republicans investigating the investigation!

AlphaFold2 continues to do lots of stuff

GPT-4 coming in the next week or so

You can’t stop AI progress

Happy News!

Toddler vaccinations are up!

The asteroid diversion was a success!

Growing Nuclear Acceptance! 

Start-up Sakuu uses 3D printers to print solid-state batteries

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Wes, Eneasz, and David discuss the news from the last two weeks from a rationalist perspective

Support us on Substack!

News discussed:

A pretty good open-source LLM with a webapp interface has been released

Iran Followup - young couple give (combined) 10year jail sentence for dancing in public (and filming it)

Iran’s Revolutionary Guard increasingly deployed in protest crack-downs.

East Palestine, Ohio local police department declares unrestricted chemical warfare on Ohio

Summary

On-the-ground footage

More

Reporters trying to find out what the heck happened getting arrested

Turkey hit with 7.8 & 7.5 mag earthquakes. 35K dead. Reports that building codes were waived for years partly responsible. 

Jobs for everyone!

H5N1 can/has spread to mammals

OpenAI released an AI safety policy proposal. It sucks unbelievable quantities of ass.

Getty Images suing Stable Diffusing for 1.8 Trillion

The eighth seal of the apocalypse has broken, and the deepfake boner pill scams have poured forth to cover the Earth

A judge in Colombia used ChatGPT to make a court ruling

Democrats made South Carolina the first primary instead of Iowa

New Hampshire is not playing ball

Covid is over… on May 11th

Happy News!

California nuked its zoning code

Developers are sharing creative ideas

India discovers 5.9m tonnes of Lithium!

Only 13 human cases of Guinea worm disease in 2022

SpaceX successfully static-fire tests Starship

A new way to significantly increase the potency of almost any vaccine has been developed by International Institute for Nanotechnology (IIN) at Northwestern University. The paper is here.

Brain Cancer Vaccine being developed

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News discussed:

Bounded distrust

The SCOTUS leak investigation fizzled out

Classified documents also found at Mike Pence’s house!

Eight in 10 people in China caught Covid since early December, say officials

Israel strikes Iranian drone plant with their own drone strike

NATO countries sending Leopard 2 main battle tanks to Ukraine, US sending Abrams 1 

Russia pushing into Donetsk, striking before tanks arrive

Huge increase in homicides is persisting

Tyr Nicoles beat to death by police earlier this month

Gas stoves became the main character of the internet for some reason

F**k that noise (Zvi)

Trump indictment decisions are “imminent” in Georgia election interference case

Conversely, New York chickenshit prosecutors failed to charge in Stormy Daniels case

“class action” copyright lawsuit filed against Stability AI, DeviantArt, and Midjourney related to Stable Diffusion.

Apparently it’s b******t

Real estate agents using ChatGPT commercially

After CA votes to keep Diablo Canyon nuclear power plant in operation, NRC says “nah”

Some auto insurers are refusing to cover certain Hyundai and Kia models

Happy News!

(fake happy news) China considers banning export of solar panel components

Climeworks pulled CO2 from the air stored it underground

Research on pain-insensitivity gene continues.

Endangered Species Act has saved hundreds from extinction

Artificial Pancreas looks to be twice as good as normal insulin injection

Troop Deployment Links

Jon Stokes’ and Construction Physics substacks are quite good. 

David recommends this piece on the Stability lawsuit And this piece on why automatic bricklayers don’t exist.

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Wes, Eneasz, and David discuss the news from the last two weeks from a rationalist perspective, with special guests appearances by Charlie and Gray!

Support us on Substack!

News discussed:

The Electoral Count Reform Act was passed

Finally got enough on the 15th ballot

Mexico captures El Chapo’s son (again) and has a literal military battle with cartels. 

Brazil’s Jan 6th happened on Jan 8th.

By one estimate, the US has sent close to 1/5th of our artillery shell stockpile to Ukraine, which will take 2yrs to replenish at current rates

Language Models can make completely de novo proteins that are viable in the wetlab. William Eden has the best take.

LLMs can discern cause & effect

When Google tuned a AI chatbot to answer common medical questions, doctors judged 92.6% of its answers right

It also passed the Official medical exam

Braced pistols now regulated under same rules as SBRs

Sexy News Update - more than 75% of casual sex isn’t ONS, it’s an extended sexual relationship with a friend/acquaintance. 

Ecuadorian man changes gender to route around sexist laws

Happy News!

South Carolina court found right to abortion in Constitution up to 20 weeks

FDA lifted rule banning mifepristone (abortion pill) from being sold in pharmacies

Tom Lehrer put all of his music in the public domain

The End Poem of Minecraft is too!

FTC is (probably) banning non-compete clauses!!

Counterpoint from Tyler Cowen

Japan is NukeMaxxing!

DUKE NUCLEAR!

In big New Atheist win, Congressman Was Sworn Into Office With Rare Superman Comic

Eneasz crossed a bridge

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Wes and David discuss the news from the last two weeks from a rationalist perspective WITHOUT Eneasz for once

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News discussed:

California court declared that anything good violates CEQA

George Santos (R-NY) is a big fat phony

Spencer Greenberg podcast featuring Elizabeth Edwards-Appell

NY “Right to Repair” law passed but made useless

a bunch of standard cell lines are THE WRONG CELLS (h/t Sarah Constantin)

Happy News!

Colorado decriminalization DMT, psilocybin, mescaline, and ibogane

Researchers deactivated the BRD8 protein that’s key to this cancer using a pioneering gene editing technique. stopped the tumor growth in its tracks

27-year-old Jay Withey saved the lives of two dozen people during the deadly storm by rescuing strangers from cars trapped in the snow and bringing them into a school for shelter.

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Show notes:

Wes, Eneasz, and David discuss the news from the last two weeks from a rationalist perspective

Support us on Substack!

News discussed:

Kirsten Synema left the Democratic Party. MAVERICK!

Jan. 6th committee referred Trump for charges

Trump Org found guilty of tax fraud

Prospera sues Honduras for approximately 30% of its GDP

SBF arrested and indicted 

bad news for school emancipation 

the Islamic Republic of Iran was just expelled from the U.N. Women's Rights Commission.

China reverses covid policy

Happy News!

Net-gain in fusion power breakthrough, kinda-sorta

Edit T-cell genomes (not gnomes) for great cancer-busting justice!

Organ-on-chips allow for direct drug testing on human tissue

Eneasz on his first rationalist solstice

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Intro/outro music: On Sale by Golden Duck Orchestra

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