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Science can’t stop aging, but it may be able to slow our epigenetic clocks. What if we could slow down the hands of our biological clocks? This question underpins much of the research of Morgan Levine, who leads a research team at the life science company Altos Labs. Levine investigates the fascinating intricacies of aging, recognizing that it doesn't happen at a uniform pace for everyone. Central to her exploration is the concept of epigenetics — the factors that influence gene activity without changing the DNA sequence. Levine focuses on DNA methylation, a significant epigenetic change that occurs with aging, and the development of models called "epigenetic clocks" that can be used to predict biological age. While she acknowledges that it might be possible to reverse aging at a cellular level, Levine clarifies that the ultimate goal is not to "cure" aging or death, but to delay disease onset and improve healthspan.
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Chapters:
0:00 Fast agers & slow agers
1:25 The hallmarks of aging
1:59 What is the epigenetic clock?
3:05 Can we ‘Benjamin Button’ aging?
5:22 The holy grail for scientists
Listen To This Next:
Adam Grant's #1 phrase to unlock potential
The science of super longevity
Beat anxiety with the most addictive experience on Earth
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Discover Big Think | Smarter Faster™
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By dash3.3
1212 ratings
Science can’t stop aging, but it may be able to slow our epigenetic clocks. What if we could slow down the hands of our biological clocks? This question underpins much of the research of Morgan Levine, who leads a research team at the life science company Altos Labs. Levine investigates the fascinating intricacies of aging, recognizing that it doesn't happen at a uniform pace for everyone. Central to her exploration is the concept of epigenetics — the factors that influence gene activity without changing the DNA sequence. Levine focuses on DNA methylation, a significant epigenetic change that occurs with aging, and the development of models called "epigenetic clocks" that can be used to predict biological age. While she acknowledges that it might be possible to reverse aging at a cellular level, Levine clarifies that the ultimate goal is not to "cure" aging or death, but to delay disease onset and improve healthspan.
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Chapters:
0:00 Fast agers & slow agers
1:25 The hallmarks of aging
1:59 What is the epigenetic clock?
3:05 Can we ‘Benjamin Button’ aging?
5:22 The holy grail for scientists
Listen To This Next:
Adam Grant's #1 phrase to unlock potential
The science of super longevity
Beat anxiety with the most addictive experience on Earth
------------------
Go Deeper with Big Think:
►Become a Big Think Member
Get exclusive access to full interviews, early access to new releases, Big Think merch and more
►Get Big Think+ for Business
Guide, inspire and accelerate leaders at all levels of your company with the biggest minds in business
------------
Discover Big Think | Smarter Faster™
Your top destination for expert-driven, educational content. Featuring thousands of episodes and insights from renowned figures like Bill Clinton to Bill Nye, Big Think accelerates your learning by delving into the pivotal concepts and essential skills shaping knowledge in the 21st century...
Unlock Knowledge, Faster
With Insights from the World's Leading Minds
Remember to Follow the Podcast and Enable Notifications
If you found this episode valuable, Share It
Leave a 5-Star Review!
Learn more about your ad choices. Visit megaphone.fm/adchoices

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