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Tesamorelin is one of the few peptides I've seen actually move the needle on body composition. So I made a full masterclass on it.

This is the user's guide as it stands in 2026. I cover what tesamorelin is, how it works, and the best practices I'd recommend for using it.

We get into the growth hormone axis and why a GHRH is different from a GHRP. I break down the clinical data, the 15% visceral fat reduction, the liver fat numbers, and the cognition research almost nobody talks about.

Then we get practical. Dosing, timing, fasted injections, and the cycling patterns I actually use. I share why I stay at one milligram instead of two and what the water retention tradeoff looks like at higher doses.

I also cover stacking with testosterone and GLP-1s, reconstitution, injection technique, side effects, and the people who should skip this one entirely.

I'm honest about the limits too. Some of this evidence is strong and some of it isn't. I tell you which is which.

If you're thinking about tesamorelin or already using it, this is everything I'd want you to know.