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Sussing out herb-drug interactions is complicated! In this episode we take the example of Celexa + skullcap, and demonstrate the process of investigation we’d use to sort out whether a proposed risk is real.

We start with the Botanical Safety Handbook, because it has certain features which make it significantly better than other manuals or databases. These include the varied relevant experience and skills of the editorial team, its clarity about real vs theorized reactions, and other critical data points which are directly relevant to the herbalist’s practice.

Checking one resource isn’t sufficient, though. We also need to consider the fact that ‘absence of evidence is not evidence of absence’, and remember that constitutional variations can significantly change the efficacy of a given herb for a particular person. Information outside of scientific studies – such as the popularity of an herb or the prevalence of a drug, as well as traditional practices with plants – can help us to orient ourselves more precisely.

For further education about herb-drug interactions:

• Herb-Drug Interactions & Herb Safety – our complete course on this subject teaches you all the ins & outs of identifying potential interactions, avoiding them, and conducting reality checks on information you encounter about these risks.
• The Botanical Safety Handbook – our #1 resource for this information.
• HHP 101: How Herbs Are Different From Drugs – a key episode of our podcast, these concepts are helpful when learning how HDI may occur.

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