The Proof with Simon Hill

This Food Swap Could Cut Your Risk of Early Death by 17% | Dr Matthew Nagra


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In today’s episode Dr Matthew Nagra returns to The Proof to break down a new JAMA Internal Medicine study on butter, plant-based oils, and mortality.

Over 200,000 Americans were followed for 33 years — so what did the research really find?


We unpack the study’s most talked-about claims, including whether swapping just 10g of butter for plant-based oil could lower your risk of early death.


Plus, we dive into the bigger picture: Why fats are so polarising, the debate around seed oils, and how to navigate nutrition science in an era of misinformation.


Specifically, we cover:

  • Inside a Controversial New Study on Butter and Plant Oils (00:00)
  • How the 33-Year Nutrition Study Was Conducted (00:47)
  • What Observational Studies Can (and Can’t) Tell Us (03:01)
  • The Truth About Food Frequency Questionnaires (08:03)
  • Surprising Patterns in Butter and Oil Consumption (17:52)
  • Why One Common Oil Performed Better Than Expected (22:50)
  • Are We Misunderstanding Nutrition Guidelines? (26:13)
  • What Happens When Oils Are Heated Over and Over (28:28)
  • Do Oils Measure Up to Whole Food Fat Sources? (31:04)
  • The Great Oil Debate: A Preview and Reflection (34:07)
  • A Smarter Way to Navigate Conflicting Health Advice (43:40)

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    This episode is brought to you by:

    38TERA

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    Simon Hill, MSc, BSc (Hons)

    • Creator of theproof.com

    • Host of The Proof with Simon Hill

    • Author of The Proof is in the Plants

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    • Instagram: @simonhill

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    Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

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