This Week in Virology

TWiV 1028: Asymptomatic SARS-CoV-2 infection and T cells


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TWiV reviews approvals of the first gene therapy for severe hemophilia A in adults and a monoclonal antibody to prevent RSV respiratory disease in babies and toddlers, and a common allele of HLA that mediates asymptomatic SARS-CoV-2 infection through pre-existing T cell immunity due to previous exposure to common cold coronaviruses.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker

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Links for this episode
  • MicrobeTV Discord Server
  • First gene therapy for hemophilia A approved (FDA)
  • Luxurna, gene therapy for vision loss (FDA)
  • Anti-RSV monoclonal antibody approved (FDA)
  • Trial of single-dose Nirsevimab (NEJM)
  • Letters read on TWiV 1028
  • Timestamps by Jolene. Thanks!
Weekly Picks

Dickson – Phoenix hits 110 degrees for the 19th day in a row, setting national record Brianne – James Webb Telescope One Year Anniversary Photo Kathy – Drone awards photos Alan – WHO Film Festival winners Vincent – Thinking, Fast and Slow by Daniel Kahneman

Listener Picks

David – The Mass Extinction Debates: A Science Communication Odyssey

Intro music is by Ronald Jenkees

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This Week in VirologyBy Vincent Racaniello

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