Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

Vincent, Dickson, Alan, Rich, and Kathy review two papers that present evidence for RNA interference as an antiviral immunity mechanism in mammals.

Links for this episode:

• World Polio Day
• Mole Day
• John Holland's publications
• RNAi is antiviral in mammals (Science)
• Antiviral RNA interference in mammals (Science)
• RNAi, antiviral after all (Science)
• Is RNA interference antiviral in mammals? (Cell Host Microbe)
• Nodamura virus (Nature)
• Ebolavirus proteins suppress RNAi (J Virol)
• Illustrated is an siRNA (orange), dicer (top right), and argonaute (bottom)
• Letters read on TWiV 256

Weekly Science Picks

Dickson - Wildlife Photographers of the Year 2013Kathy - John Holland's Emerging Infectious Disease lecture (YouTube)Alan - The worst part is notRich - The Universe in a Single Atom by Dalai Lama (Mind and Life Institute)Vincent - The Truth about T. Rex by Brian Switek

Listener Pick of the Week

Stephen - International Institute for Species Exploration (Top 10 species choice)

Send your virology questions and comments (email or mp3 file) to [email protected]