Ned Landau joins the TWiV team to discuss restriction of HIV replication by SAMHD1, and a viral antagonist that can be used to produce a dendritic cell vaccine.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker

Guest: Ned Landau

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Links for this episode

• Support Viruses Gordon Conference
• TWiV #124 September 2008
• SAMHD1 restricts HIV-1 replication (Nature)
• SAMHD1 restricts diverse retroviruses (Retrovirology)
• Vpx degradation of SAMHD1 independent of uncoating (J Virol)
• Transduction of myeloid cells with Vpx vector (Gene Ther)
• Letters read on TWiV 511
• Timestamps by Jolene. Thanks!

Weekly Science Picks

Brianne- Online Immunology Course Alan- Bacteria Builder Rich- 2018 Ig Nobel Prizes Dickson- Between Fear and Hope Ned - HUSH silencing of transposons Vincent - Paywall publishing ban (Schlitz statement); Curry on DORA

Listener Pick

Steve- Paywall: Business of Scholarship and Biohazard Islam- Peer review Twitter post

Intro music is by Ronald Jenkees.

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