TWiV reviews the difficulties in predicting species susceptibility to SARS-CoV-2 infection by only examining the ACE2 protein, and the olfactory mucosa as a portal of entry into the central nervous system in COVID-19 patients.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

Guest: Amy Rosenfeld

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Links for this episode

• NYC will create pandemic response institute (NY Bus J)
• Comparison of ACE2 in vertebrates (PNAS)
• Olfactory transmucosal invasion of CNS by SARS-CoV-2 (Nat Neurosci)
• Letters read on TWiV 690
• Timestamps by Jolene. Thanks!

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Dickson – National Geographic best animal photos of 2020 Amy – American Contagions: Epidemics and the law from Smallpox to COVID-19 by John Fabian Witt Alan – HamSCI citizen science organization Rich – DeepMind's AI makes gigantic leap in solving protein structures Vincent – Army Ants: Nature's Ultimate Social Hunters by Daniel Kronauer

Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]