Alessandro Sette joins TWiV to discuss the role of T cells in COVID-19, the finding that amino acid changes in SARS-CoV-2 variants of concern have a negligible impact on T cell reactivity in convalescent patients and vaccinees, and whether a next generation vaccine should include more viral proteins than spike.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler

Guest: Alessandro Sette

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Links for this episode

• Little impact of SARS-CoV-2 variants on T cell reactivity (bioRxiv)
• NIDO 2021 Symposium
• Postdoctoral position at Towson University
• ASV hosts free COVID-19 Vaccine Education Town Halls (register here)
• Letters read on TWiV 736
• Timestamps by Jolene. Thanks!

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Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]