TWiV reviews the emergence of remdesivir-resistant SARS-CoV-2 during treatment of a persistently infected immunocompromised patient, and how altered TMPRSS2 utilization by the Omicron variant influences infectivity and fusion.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker

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Links for this episode

• ASV 2022
• Emergence of remdesivir resistance (Nature Comm)
• How to stall a copy machine (TWiV 819)
• Omicron altered TMPRSS2 usage (Nature)
• Timestamps by Jolene. Thanks!

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Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]