Vincent travels to Cornell University to speak with Gary Whittaker about regulation by proteolytic processing of the fusion activity of the spike protein of SARS-CoV-2, and feline coronavirus transmission, replication and disease.

Hosts: Vincent Racaniello

Guest: Gary Whittaker

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Links for this episode

• SARS-CoV-2 spike and its furin cleavage site (Lancet Microbe)
• TMPRSS2 inhibitor blocks SARS-CoV-2 reproduction (Nature)
• Distinct spike proteins of feline coronaviruses (Viruses)
• Feline coronavirus and feline infectious peritonitis (J Zoo Wild Med)
• Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]