This Week in Virology

TWiV 964: Clinical update with Dr. Daniel Griffin


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In his weekly clinical update Dr. Griffin discusses Dr. Griffin discusses progress toward poliomyelitis eradication in Afghanistan, reduced risk for Mpox after receipt of 1 or 2 doses of JYNNEOS vaccine compared with risk among unvaccinated persons, reduced airborne transmission of SARS-CoV-2 BA.1 Omicron virus in Syrian hamsters, authorized updated (Bivalent) COVID-19 vaccines for children down to 6 months of age, low neutralization of SARS-CoV-2 Omicron BA.2.75.2, BQ.1.1, and XBB.1 by parental mRNA vaccine or a BA.5-bivalent booster, efficacy of antiviral agents against omicron subvariants BQ.1.1 and XBB, incidence of viral rebound after treatment with Nirmatrelvir-Ritonavir and Molnupiravir, and the effectiveness of coronavirus disease 2019 (COVID-19) vaccine in the prevention of post–COVID-19 conditions.

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Links for this episode
  • Progress toward Poliomyelitis eradication in Afghanistan (CDC)
  • Reduced risk for Mpox after receipt of 1 or 2 Doses of JYNNEOS vaccine (CDC)
  • Reduced airborne transmission of BA.1 Omicron virus in Syrian hamsters (PLOS)
  • Authorized bivalent vaccines for children down to 6 months of age (FDA)
  • Low neutralization of BA.2.75.2, BQ.1.1, and XBB.1 by parental mRNA vaccine (Nature)
  • Efficacy of antiviral agents against Omicron subvariants BQ.1.1 and XBB (NEJM)
  • Viral rebound after treatment with Nirmatrelvir-Ritonavir and Molnupiravir (JAMA)
  • Paxlovid patient eligbiliity screening checklist (FDA)
  • Effectiveness of COVID-19 vaccines in prevention of post–infection conditions (ASHE)
  • Contribute to our MicrobeTV fundraiser at PWB
  • Dr. Griffin's treatment guide (pdf)
  • Letters read on TWiV 964
  • Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

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