In his weekly clinical update Dr. Griffin discusses confronting the evolution and expansion of anti-vaccine activism in the USA in the COVID-19 era, the effectiveness of maternal Influenza vaccination in Peru, characteristics and predictors of persistent symptoms post-COVID-19 in children and young people, parental nonadherence to health policy recommendations for prevention of COVID-19 transmission among children, community-onset bacterial coinfection in children critically ill with SARS-CoV-2 infection, bivalent booster effectiveness against severe COVID-19 outcomes in Finland, viral kinetics of sequential SARS-CoV-2 infections, risk of COVID-19 associated pulmonary aspergillosis based on corticosteroid duration in intensive care patients, immunomodulators for severe COVID19 in transplant patients: do they increase the risk of secondary infection, long-term cardiovascular outcomes in COVID-19 survivors among non-vaccinated population, cardiac abnormalities in Long COVID 1-year post-SARS-CoV-2 infection, one-year adverse outcomes among us adults with Post–COVID-19 condition vs those without COVID-19 in a large commercial insurance database, and long-term gastrointestinal outcomes of COVID-19.

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Links for this episode

• Confronting the evolution and expansion of anti-vaccine activism (The Lancet) 
• Effectiveness of maternal influenza vaccination in Peru (OFID)
• Characteristics and predictors of persistent symptoms post-COVID-19 (BMJ)
• Parental nonadherence to health policy recommendations for prevention of COVID-19 (JAMA)
• Community-onset bacterial coinfection in children ill with SARS-CoV-2 infection (OFID)
• Bivalent booster effectiveness against severe COVID-19 outcomes (medRxiv) 
• Viral kinetics of sequential SARS-CoV-2 infections (medRxiv)
• Risk of COVID-19 associated pulmonary aspergillosis based on corticosteroid duration in ICU patients (OFID)
• Immunomodulators for severe COVID-19 in transplant patients (TID)
• Long-term cardiovascular outcomes in COVID-19 survivors among non-vaccinated population (eClinicalMedicine) 
• Cardiac abnormalities in Long COVID 1-year post-SARS-CoV-2 infection (BMJ)
• One year adverse outcomes among US adults with post COVID-19 condition vs those without COVID-19 (JAMA)
• Long-term gastrointestinal outcomes of COVID-19 (Nature)
• Contribute to our ASTMH fundraiser at PWB
• Dr. Griffin’s treatment guide (pdf)
• Letters read on TWiV 990
• Don’t crush Paxlovid (pdf)
• Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]