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Your gut microbiome doesn't stay the same through perimenopause—it changes, and that shift explains why digestion suddenly becomes unpredictable, why foods you tolerated for decades now trigger bloating, and why symptoms you never had before show up out of nowhere.
Gut health and hormones are not separate—they’re wired together.
In this episode of Medical Disruptors, I sit down with Dr. Christine Maren to reveal the gut–hormone connection almost no one is talking about. We dig into how hormone changes in midlife rewire the gut microbiome, disrupt balance, and trigger bloating, brain fog, and mood swings.
But this isn’t only about menopause. Your microbiome, your hormones, and your stress response form a feedback loop. Hormones shape the gut. The gut shapes hormones. Stress fuels both. Everyone lives in this cycle—though it hits hardest for women in their 40s and beyond.
That’s why midlife symptoms show up—or intensify—when hormones decline. And it’s why you don’t have to accept them as “normal.”
If you’re looking for hacks, keep scrolling. This conversation is about the long game—real resilience, balance, and solutions that last.
Watch now to change the way you think about gut health, hormones, and midlife—and don’t forget to subscribe for more episodes of Medical Disruptors.
Looking to schedule a consultation with Dr. E? Book here: drefratlamandre.com/consult
Learn more about your ad choices. Visit megaphone.fm/adchoices
By Dr. Efrat LaMandre PhD, FNP-C5
4141 ratings
Your gut microbiome doesn't stay the same through perimenopause—it changes, and that shift explains why digestion suddenly becomes unpredictable, why foods you tolerated for decades now trigger bloating, and why symptoms you never had before show up out of nowhere.
Gut health and hormones are not separate—they’re wired together.
In this episode of Medical Disruptors, I sit down with Dr. Christine Maren to reveal the gut–hormone connection almost no one is talking about. We dig into how hormone changes in midlife rewire the gut microbiome, disrupt balance, and trigger bloating, brain fog, and mood swings.
But this isn’t only about menopause. Your microbiome, your hormones, and your stress response form a feedback loop. Hormones shape the gut. The gut shapes hormones. Stress fuels both. Everyone lives in this cycle—though it hits hardest for women in their 40s and beyond.
That’s why midlife symptoms show up—or intensify—when hormones decline. And it’s why you don’t have to accept them as “normal.”
If you’re looking for hacks, keep scrolling. This conversation is about the long game—real resilience, balance, and solutions that last.
Watch now to change the way you think about gut health, hormones, and midlife—and don’t forget to subscribe for more episodes of Medical Disruptors.
Looking to schedule a consultation with Dr. E? Book here: drefratlamandre.com/consult
Learn more about your ad choices. Visit megaphone.fm/adchoices

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