Genetics is one of the hottest topics in health—but it’s also one of the most misunderstood.

In this episode of The Autoimmune Doc Podcast, Dr. Taylor Krick sits down with Dr. Tyler Panzner PhD to talk about how genetics can actually be used to optimize health—without falling into the trap of thinking genes replace the fundamentals (diet, movement, sleep, stress, and lifestyle).

Dr. Tyler shares how his own 23andMe results sparked a deep dive into genetic pathways, why “one-size-fits-all” supplement advice can backfire (especially for sensitive nervous systems), and how to think in terms of biochemical bottlenecks and “big levers” instead of overwhelm-inducing data dumps.

What You’ll Learn in This Episode:

-Why genetics can be helpful… but never replaces lifestyle basics (eat well, move well, sleep well, breathe well)

-The difference between SNPs/variants, alleles, and what heterozygous vs. homozygous really means

-Why “having the MTHFR gene” isn’t the point—everyone has the gene, many have mutation(s), his question is - how well is it functioning?

-Tyler’s practical framework: finding your biggest biochemical bottlenecks instead of chasing 300-page genetic reports

-A nuanced take on precision supplementation (and why “TikTok Shop protocols” can create new problems)

-The COMT gene explained: how it impacts dopamine, adrenaline/noradrenaline, estrogen, and even personality tendencies

-Why some people feel amazing on certain supplements… and others get anxiety, insomnia, heart palpitations, or overstimulation

-How popular flavonoids like quercetin can be a hidden issue for some (even when taken “for allergies” or “for inflammation”)

-Why vitamin D status isn’t just about the blood level—receptors + conversion enzymes can change the whole story

-A behind-the-scenes look at why genetics research isn’t always “clean” or easy to study (and why clinical pattern recognition matters)


Guest Info:

Dr. Tyler Panzner, PhD
Website: https://drtylerpanzner.com/


If you’ve ever tried “the right supplement” and felt worse… or you’ve been told your genes are a “life sentence”… this conversation will give you a clearer, calmer, and more empowering way to think about genetics and healing.