March 22, 2024

109. Methylene Blue - Oxygen Delivery & Utilization, Mitochondrial Hacking, Antimicrobial Benefits, & The Effect on The Gut Microbiome (+ My Thoughts on Supplementation)

30 minutes

We uncover the various capabilities of methylene blue, particularly its pivotal roles in enhancing mitochondrial function, optimizing energy production, and facilitating oxygen delivery. We also dive into the question of whether its antimicrobial properties impact the gut microbiome in a positive or negative way. Lastly, we explore the downstream effects of improved mitochondrial function, including cognitive and mood enhancement and potential anti-aging benefits.

Topics:

What is Methylene Blue?

Synthetic dye with applications in medicine, biology, and chemistry

Antimicrobial properties and electron transfer capabilities

The Electron Accepting and Donating Aspect

Importance in mitochondrial function and energy production

Comparison with NAD+ and NADH

Application and Use in Methemoglobinemia

Definition and implications of methemoglobinemia

Environmental toxins increasing methemoglobin levels

Role of methylene blue in reducing methemoglobin

Highlighting Methylene Blue's Mechanism

Electron transfer to methemoglobin

Restoring oxygen-carrying capacity by restoring hemoglobin

Metabolism and excretion of methylene blue

Methylene Blue in Mitochondrial Energy Production

Function in the electron transport chain (ETC)

Bypassing disruptions (due to damage/disease) in the ETC

Enhancing ATP synthesis

Broader Applications and Antimicrobial Properties

Photodynamic therapy and photoactivated disinfection

Efficacy against a wide range of microorganisms

What does it do to the gut microbiome, though?

Supplementation routes, dose used in studies, bioavailability

Cognitive and Anti-aging Effects

Impact on cognitive function and memory

Potential anti-aging benefits

Studies on neuroprotection and mood enhancement

Thank you to our episode sponsors:

Dr. Morse's Daily Detox Kit

Veri CGM (use code: VSM-THESYNTHESISOFWELLNESS)

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By Chloe Porter

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