The Synthesis of Wellness®

110. Intracellular NAD+ Testing, My Self-Experimentation, And Optimizing NAD+ Synthesis (Supporting The Salvage Pathway, Inhibiting CD38 Enzyme, & More)


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In this episode, we delve into intracellular NAD+ testing and explore self-experimentation aimed at optimizing NAD+ synthesis. From supporting the salvage pathway, de novo synthesis, and the Preiss-Handler pathway to inhibiting the CD38 enzyme, we will uncover some key nutrients and precursors that will enhance NAD+ stores and production.


Topics:

1. Importance of NAD+

- Cellular processes involving NAD+

- NAD+ as a coenzyme for numerous enzymes

- Focus on energy metabolism


2. Energy Metabolism and NAD+

- Glycolysis and NAD+

- Krebs cycle and NAD+

- Electron transport chain and ATP production


3. Disruption of NAD+ to NADH Ratio

- Inhibition of electron transport chain

- Role of reactive oxygen species (ROS)


4. Strategies to Restore NAD+ Levels

- De novo synthesis pathway of NAD+

- Preiss-Handler Pathway

- Salvage pathway

- Supporting pathways with supplements

- CD38 Enzyme inhibition: how and why?


5. Personal Experimentation and Results Sharing

- Self-experimentation to optimize intracellular NAD+

- Reporting results of experimentation

Thank you to our episode sponsor:

⁠Dr. Morse's Daily Detox Kit



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The Synthesis of Wellness®By Chloe Porter

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