June 07, 2024

123. Babesia (Lyme Co-infection) Part 2 - Anti-malarial Supplements, Proteolytic Enzymes to Break up Parasitic/Fibrin Nests, and Methylene Blue

23 minutes

In this part 2 episode, we dive into the pathology and symptoms of Babesiosis, exploring how the Babesia parasite infects red blood cells and evades the immune system. We discuss various labs and biomarkers to look out for. We then address various treatment protocols featuring anti-malarials including herbal supplements such as artemisinin and cryptolepis, and proteolytic enzymes like lumbrokinase and nattokinase. Additionally, we cover the use of methylene blue and its impact on Babesia parasites.

Topics:

1. Introduction

- Brief overview of Babesiosis and previous discussion

- Overview of Babesia infection and its impact on red blood cells (RBCs)

2. Pathology of Babesiosis

- Infection and multiplication within RBCs

- Mechanisms of immune evasion

- Expression of specific proteins on RBC surface

- Adherence to capillary endothelial cells

- Avoidance of spleen clearance

- Antigenic variation and immune system evasion

3. Symptoms of Babesiosis

- Air hunger

- High fever

- Severe fatigue

- Muscle and joint pain

- Persistent headaches

- Jaundice

- Dark urine

- Organ failure (in severe cases)

4. Labs and Markers for Babesiosis

- Hematological markers

- Hemolytic anemia

- Thrombocytopenia

- Leukopenia

- Hemoglobinuria

- Hyperbilirubinemia

- Elevated LDH levels

- Reticulocytosis

- Other markers

- High C4a levels

- Low CD57 count

5. Protocols

- Importance of medical supervision and potential Herxheimer reaction

- Overview of treatment approaches

6. Anti-Malarial Protocols for Babesiosis

- Prescription Medications

- Mepron (Atovaquone), Mechanism of action: inhibition of mitochondrial electron transport chain.

- Azithromycin, Mechanism of action: blocking protein synthesis.

- Herbal Approaches for Babesiosis

- Artemisinin: Derived from sweet wormwood plant. Mechanism of action: production of reactive oxygen species (ROS).

- Cryptolepis: Bioactive compound is Cryptolepine, Mechanism of action: disruption of DNA synthesis.

7. Proteolytic Enzymes

- Lumbrokinase

- Nattokinase

8. Methylene Blue

- Synthetic dye

- Mechanism of action: disrupting mitochondrial function and generating ROS within Babesia

- Administration methods and effects

9. Conclusion

- Recap of supplements and treatments discussed

- Emphasis on individualized treatment plans, bioindividuality, and working with a medical physician

Thank you to our episode sponsor: ⁠Liver Medic⁠

Use code Chloe20 to save 20% on ⁠⁠"Leaky Gut Repair"⁠⁠

⁠⁠Brendan's YouTube Channel⁠⁠

⁠⁠https://x.com/livermedic⁠⁠

Thanks for tuning in!

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By Chloe Porter

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