The Longevity & Lifestyle Podcast

#230 The Future of Health Optimization: Diagnostics, Stem Cells & Scaling Longevity for Everyone With Jim Donnelly


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What if health optimization wasn’t just for the elite — but something every teacher, firefighter, and family could access?

In this inspiring episode, Jim Donnelly, founder and CEO of Humanaut Health (and former founder of Restore Hyper Wellness), shares how he’s building the most comprehensive, prevention-driven longevity model to date. From advanced diagnostics and regenerative medicine to behavior change and coaching, Jim reveals what it truly takes to add 10–20 healthy, vibrant years to life.

He opens up about the loss of his father, surviving a near-fatal car accident, and how stem cell therapy transformed his recovery — all of which shaped his mission to scale health optimization with integrity, accessibility, and world-class medical excellence.

We explore:

  • Why foundational habits (sleep, movement, nutrition, stress) drive 90% of results
  • How Humanaut uses 150+ diagnostics to find root causes
  • Why regenerative medicine works best on a healthy foundation
  • How to democratize longevity without sacrificing quality
  • What it takes to reverse metabolic dysfunction — 86% success in under 6 months


This conversation is a powerful reminder that the future of medicine is preventive, personalized, and incredibly hopeful.

Tune in and discover what’s possible when we invest in health — not after we’re sick, but while we’re thriving.



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The Longevity & Lifestyle PodcastBy Claudia von Boeselager

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