Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health

24. Histamine & Anxiety – How High Histamine Triggers Fight-or-Flight Symptoms


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Can histamine be the hidden reason behind your anxiety?

In this episode, I break down how histamine acts as a neurotransmitter in the brain — and why an overload can leave you wired, anxious, and unable to relax. We dive into how methylation, estrogen, mold, and gut inflammation (including SIBO and oxalates) all feed into the histamine-anxiety loop.

Whether you're a practitioner treating patients with anxiety or someone who’s tried everything to feel better — this episode gives you a deeper lens into the hidden biochemical drivers of mental health symptoms.

If you've ever felt overstimulated, panicked, or like anxiety hits out of nowhere, you're going to want to hear this one.



✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

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Histamine Well Podcast: Exploring Histamine, Methylation & Holistic HealthBy Joanne Kennedy

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