The Synthesis of Wellness®

28. Candida Toolkit - Breaking Down Biofilms, Antifungals, Attacking the Fungal Cell Wall, Blocking Fungal Cell Adhesion to the Gut Mucosa, & More


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In today's episode, we will delve into a research-backed candida toolkit, exploring the cellular structure of candida microbes and presenting scientifically supported strategies to target and eliminate candida overgrowth. Thank you so much for tuning in!


Topics:


1. Understanding candida

- Overview of candidiasis and Candida albicans

- Candida albicans as part of the body's microbiota


2. Symptoms and related conditions of candida overgrowth

- Digestive symptoms (bloating, gas, diarrhea, constipation)

- Fatigue and recurrent yeast infections

- Cognitive and mood symptoms (brain fog, difficulty concentrating, mood swings)

- Skin and nail infections, sugar cravings


3. Candida's metabolic pathways and adaptability

- Fuel sources for Candida albicans (glucose, fructose, galactose)

- Cell wall composition and remodeling

- Moonlighting proteins and adaptability

- Transition from yeast to hyphal form


4. Strategies to address candida overgrowth

- Blocking fungal cell wall and immune evasion

  • Beneficial gut bacteria (L. rhamnosus, L. johnsonii)
  • Echinocandin antifungal medications?
  • Caprylic acid (found in coconut oil)

  • - Blocking fungal cell adhesion

    • Beneficial gut microbes antagonizing candida adhesion sites
    • Rosemary as an adhesion inhibitor
    • LL-37 peptide as an adhesion blocker

    • - Blocking biofilm formation or destroying biofilms

      • Short-chain fatty acids produced by beneficial gut bacteria
      • Carvacrol and thymol (found in oregano)

      • - Blocking the yeast to hyphal transition

        • Butyrate (short-chain fatty acid)

        • - Blocking key pathways for candida albicans cell proliferation or metabolism

          • Azole antifungal medications?
          • Chinese skullcap
          • Allicin (found in garlic)
          • Low-sugar or anti-candida diet

          • - Enhancing anti-fungal immune activity

            • Butyrate (boosting macrophage antifungal activity)

            • 5. Conclusion

              - Summary of candida strategy toolkit

              - Importance of a holistic approach to address candida overgrowth

              Thanks for tuning in!

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              Thanks again for tuning in!


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              The Synthesis of Wellness®By Chloe Porter

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