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In today's episode, we are diving into NAD+ and exploring how it is a critical component for breaking down fuel, such as glucose, and ultimately converting that fuel to ATP. We will explore various factors that deplete NAD+ or decrease the NAD+/NADH ratio as well as 6 proven strategies to increase NAD+ within the body. Lastly, we wrap up the episode with a conversation pertaining to the use of NAD+ therapy for CIRS/Biotoxin illness, specifically Mold Illness. Thanks so much for tuning it!
Topics:
1. Understanding NAD+ and Its Role
- Definition of NAD+ and NADH
- Explanation of coenzymes in chemical reactions
- NAD+ and NADH as coenzymes for electron transfer
- Role in glucose metabolism and energy production
- Importance of NAD+ for various cellular functions
2. Glycolysis and NAD+
- Illustration of glucose metabolism and insulin release
- Role of GLUT4 transporters in glucose entry into cells
- Introduction to glycolysis and its steps
- Role of NAD+ as a coenzyme in glycolysis
- Generation of NADH during glycolysis
3. TCA (Krebs) Cycle and NAD+
- Transition of pyruvate to acetyl-coA
- Overview of the krebs cycle and its steps
- NAD+ as a coenzyme in the krebs cycle
- Accumulation of NADH during the cycle
4. Electron Transport Chain and NADH
- Movement of pyruvate into the mitochondria
- Role of NADH as an electron donor in the electron transport chain (ETC)
- ATP production through the ETC
5. Factors Disrupting NAD+ Balance
- Impact of toxins and pesticides on the ETC
- Role of drugs, like NSAIDs, in inhibiting the ETC
- Generation of reactive oxygen species (ROS)
- Role of ROS in mitochondrial damage and NAD+ depletion
- Link between NAD+ decline and aging
6. Consequences of NAD+ Depletion
- Effect of NAD+ reduction on metabolism
- Connection between NAD+ and metabolic diseases
- Therapeutic potential of NAD+ in age-related diseases
7. 6 Strategies for NAD+ Restoration
- Which supplemental NAD+ precursors are more effective
- Inhibition of the CD38 enzyme using dietary nutrients
- NAD+ IVs and patches: cost and quality
- Intermittent fasting
- Exercise and NAD+
- Other less well-known lifestyle factors that have a big impact on NAD+
8. NAD+ Therapies to Support Recovery from Mold Illness
- Link between NAD+ depletion and mold illness
- Thoughts on and logic behind the use of NAD+ therapies for CIRS recovery
Thanks for tuning in!
If you liked this episode, please leave a rating and review or share it to your stories over on Instagram. If you tag @synthesisofwellness, Chloe would love to personally thank you for listening!
Follow Chloe on Instagram @synthesisofwellness
Follow Chloe on TikTok @chloe_c_porter
Visit synthesisofwellness.com to purchase products, subscribe to our mailing list, and more!
Or visit linktr.ee/synthesisofwellness to see all of Chloe's links, schedule a BioPhotonic Scanner consult with Chloe, or support the show!
Thanks again for tuning in!
4.8
6161 ratings
In today's episode, we are diving into NAD+ and exploring how it is a critical component for breaking down fuel, such as glucose, and ultimately converting that fuel to ATP. We will explore various factors that deplete NAD+ or decrease the NAD+/NADH ratio as well as 6 proven strategies to increase NAD+ within the body. Lastly, we wrap up the episode with a conversation pertaining to the use of NAD+ therapy for CIRS/Biotoxin illness, specifically Mold Illness. Thanks so much for tuning it!
Topics:
1. Understanding NAD+ and Its Role
- Definition of NAD+ and NADH
- Explanation of coenzymes in chemical reactions
- NAD+ and NADH as coenzymes for electron transfer
- Role in glucose metabolism and energy production
- Importance of NAD+ for various cellular functions
2. Glycolysis and NAD+
- Illustration of glucose metabolism and insulin release
- Role of GLUT4 transporters in glucose entry into cells
- Introduction to glycolysis and its steps
- Role of NAD+ as a coenzyme in glycolysis
- Generation of NADH during glycolysis
3. TCA (Krebs) Cycle and NAD+
- Transition of pyruvate to acetyl-coA
- Overview of the krebs cycle and its steps
- NAD+ as a coenzyme in the krebs cycle
- Accumulation of NADH during the cycle
4. Electron Transport Chain and NADH
- Movement of pyruvate into the mitochondria
- Role of NADH as an electron donor in the electron transport chain (ETC)
- ATP production through the ETC
5. Factors Disrupting NAD+ Balance
- Impact of toxins and pesticides on the ETC
- Role of drugs, like NSAIDs, in inhibiting the ETC
- Generation of reactive oxygen species (ROS)
- Role of ROS in mitochondrial damage and NAD+ depletion
- Link between NAD+ decline and aging
6. Consequences of NAD+ Depletion
- Effect of NAD+ reduction on metabolism
- Connection between NAD+ and metabolic diseases
- Therapeutic potential of NAD+ in age-related diseases
7. 6 Strategies for NAD+ Restoration
- Which supplemental NAD+ precursors are more effective
- Inhibition of the CD38 enzyme using dietary nutrients
- NAD+ IVs and patches: cost and quality
- Intermittent fasting
- Exercise and NAD+
- Other less well-known lifestyle factors that have a big impact on NAD+
8. NAD+ Therapies to Support Recovery from Mold Illness
- Link between NAD+ depletion and mold illness
- Thoughts on and logic behind the use of NAD+ therapies for CIRS recovery
Thanks for tuning in!
If you liked this episode, please leave a rating and review or share it to your stories over on Instagram. If you tag @synthesisofwellness, Chloe would love to personally thank you for listening!
Follow Chloe on Instagram @synthesisofwellness
Follow Chloe on TikTok @chloe_c_porter
Visit synthesisofwellness.com to purchase products, subscribe to our mailing list, and more!
Or visit linktr.ee/synthesisofwellness to see all of Chloe's links, schedule a BioPhotonic Scanner consult with Chloe, or support the show!
Thanks again for tuning in!
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