Are you suffering from gastrointestinal distress? People with hypermobility disorders have a higher prevalence of GI problems than the general population. 

Dr. Leonard Weinstock, board-certified gastroenterologist with expertise in Ehlers-Danlos Syndromes (EDS) and related disorders, sits down with Bendy Bodies to discuss this very topic. Dr. Weinstock discusses the “unhappy triad" of EDS, postural orthostatic tachycardia syndrome (POTS), and mast cell activation syndrome (MCAS) and how MCAS may actually be at the heart of EDS. He lists ways to be evaluated for GI disorders and speculates that 10-17% of the general population may have undiagnosed MCAS. He stresses the importance of a multi-disciplinary approach to treatment and thinking outside the box. 

We look at gastroparesis and small bowel intestinal overgrowth (SIBO) and their links to hEDS and hypermobility spectrum disorder (HSD), and Dr. Weinstock outlines the prevalence of median arcuate ligament syndrome (MALS) in people with MCAS or POTS. He elaborates on his prescribing practices with low-dose naltrexone (LDN) to help increase endorphin production and reduce inflammation, and lists vitamins and diet changes that can be effective in people with MCAS. 

As one of the authors of "Covid-19 hyperinflammation and post-Covid-19 illness may be rooted in mast cell activation syndrome", Dr. Weinstock discusses the possible link between long-COVID 19 illness and MCAS. And finally, he shares suggestions on what to do if you’re having difficulty finding a GI specialist who understands complicated disorders like EDS and MCAS. 

For anyone dealing with GI issues, as well as physicians looking to understand the connection between hypermobility and GI disorders, this is a timely and important podcast. 

https://www.gidoctor.net/provider/leonard-weinstock-md https://pubmed.ncbi.nlm.nih.gov/32328892/ https://pubmed.ncbi.nlm.nih.gov/32920235/ https://www.researchgate.net/publication/338327834_Perioperative_Care_in_Patients_with_Ehlers_Danlos_Syndromes 

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