Architect of Resilience

#36: Nathalie Niddam - Foundations First: Peptide Wisdom & Resilience


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Today, we're excited to dive deep into the science and strategy of healing, aging, and true resilience with Natalie Nidham—a renowned peptide and bioregulator expert, host of the Longevity with Natalie Nidham podcast, and founder of one of the world's largest peptide communities.

In this conversation, Chris Duffin sits down with Natalie to explore her journey from holistic nutrition to becoming a trusted leader in the world of cellular optimization and biohacking. With her uniquely grounded, systems-based approach, Natalie shares why building real resilience starts from the inside out—and why peptides are only one piece of the puzzle.

Learn more about Nathalie's work here: https://www.natniddam.com

This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by:

Enhanced Executive Peptides: https://shop.enhancedexecutive.com

🔹 Lifestyle is the Foundation Peptides and supplements are powerful, but real, lasting change begins with the basics: sleep, nutrition, stress management, and movement. Without a strong foundation, high-level interventions just won't stick.

🔹 Peptides as Strategic Support, Not a Cure-All Used wisely, peptides can accelerate healing and provide "quick wins" when someone's struggling to get traction—but they should be paired with foundational changes, not used as shortcuts.

🔹 Test, Observe, Adapt Data from wearables like the Oura Ring and continuous glucose monitors can reveal trends, but it's the long-term patterns—not single-night stats—that matter. Effective protocols are built on critical thinking, ongoing feedback, and personalization.

00:00 "Resilience and Peptide Science"

08:53 Critical Thinking in Healing

12:28 "Building a Solid Foundation"

17:05 Cell Health for Optimal Function

22:32 Mitochondrial Optimization Strategies

27:46 Tracking Trends in Health Metrics

42:16 "Bioregulators: Repairing Epigenetic Errors"

42:52 Histones, Ketones, and Synergy

49:33 Bioregulators: Limits and Potential

59:22 "Mother Nature's Playbook Explained"

Learn & Connect at https://chrisduffin.com/

• SHOP: Explore my books and products in the store.

• EDUCATE: Unlock access to my incredible Education Portal featuring hundreds of hours of courses and thousands of guided movement videos, all conveniently indexed for easy navigation.

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Architect of ResilienceBy Chris Duffin

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