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In this episode, Dr. Daphna Barbeau is joined by Dr. Neal Halfon (UCLA) and Dr. Shirley Russ (Cedars-Sinai/UCLA), two leading voices in life course health development, to explore how this framework reshapes our understanding of preterm infant care and follow-up. Together, they discuss their article, Ensuring Optimal Outcomes for Preterm Infants After NICU Discharge: A Life Course Health Development Approach to High-Risk Infant Follow-Up.

Dr. Halfon introduces the seven principles of life course health development—development, unfolding, complexity, timing, plasticity, thriving, and harmony—and explains how each reveals the dynamic, multilayered nature of health trajectories. Far from abstract, these principles highlight how small adjustments in the NICU can shape long-term outcomes, with early interventions compounding over time.

Dr. Russ reflects on how harmony across biology, family, and society is essential, while also emphasizing the risks posed by mismatches between development and environment. The discussion expands to consider how interventions can be more developmentally tailored, family-centered, strength-based, and designed for long-term optimization rather than short-term problem detection.

This episode encourages neonatal professionals to see beyond the walls of the NICU, adopting a design mindset that views care as a team process and recognizes the far-reaching impact of early decisions on a child’s ability not just to survive, but to thrive.

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As always, feel free to send us questions, comments, or suggestions to our email: [email protected]. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

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