Could a "female" hormone be the missing link to resolving anxiety, inflammation, and low energy in your male patients? What if the conventional wisdom that progesterone is useless for men is not only wrong, but dangerously outdated? In episode 46 of The Nico Misleh Podcast, host Nico Misleh dismantles the long-held myths surrounding progesterone in men's health. Discover the surprising new evidence showing its powerful anti-inflammatory effects, its role in improving mitochondrial function for more energy, and its neuroprotective qualities that could be vital for mental health and managing stress. This episode provides a vital clinical perspective on why and how to consider progesterone as part of a comprehensive hormone optimization strategy, moving beyond testosterone alone to achieve superior patient outcomes.

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Chapters:

0:00 - Should Men Take Progesterone? A Clinician's Definitive Answer 

1:24 - What Hormone TRULY Separates Men and Women? (It's Not Estrogen) 

3:11 - Why Most Doctors Are WRONG About Progesterone in Men 

4:13 - The "Junk Hormone" Myth: Why Your Body Doesn't Waste Resources 

5:19 - What Is DHT and Why Is It Vital for BOTH Sexes? 

6:49 - How A Progesterone "Side Effect" Cures Anxiety & Insomnia 

8:04 - Are You Progesterone Resistant? A New Health Epidemic 

9:34 - Does Progesterone Cause Inflammation in Men? A Look at the Conflicting Science 

12:30 - How Progesterone Fights Deadly Inflammation (The COVID-19 ICU Study) 

16:15 - A Surprising Link: How Progesterone Levels Correlate with Suicide Risk in Veterans 

19:49 - The Connection Between Traumatic Brain Injury (TBI) and Low Hormones 

22:07 - Gas vs. Brake Pedal: How Hormones Control Your Nervous System 

23:04 - Meet the "Mother of All Hormones" and Her Calming Family 

25:34 - Is Your Brain on Fire? The Glutamate vs. GABA Battle for Your Mood 

26:56 - How a Patented Drug Mimics Progesterone to Treat PMDD & Postpartum 

29:22 - Can Men Get the Same Calming Brain Benefits from Progesterone as Women? 

30:52 - How Progesterone Acts as Your Body's Master Stress Regulator 

32:17 - The Ultimate Health Principle: Why Energy is the Currency of Life 

35:24 - How Aging Is a Disease of Energy Loss at the Cellular Level 

37:26 - When Should a Clinician Prescribe Progesterone for a Male Patient? 

38:45 - What Makes Men, Men? The Critical Role of Dihydrotestosterone (DHT) 

40:06 - How to Treat Anxiety in Men: Testosterone First, Then Progesterone 

41:19 - Can Progesterone Help with BPH and Prostate Health? 

42:33 - How TRT Can Shut Down Your Body's Natural Hormone Production 

45:14 - Are Human Beings a "Complicated" or "Complex" System? 

47:22 - The #1 Rule of Hormone Therapy: 1+1 Does Not Always Equal 2 

48:18 - How to Join the HRT University Community & Nico's Daily Newsletter