Modern Thyroid and Wellness

48: Beyond the Hype – The Truth About GLP-1s, Weight Loss & Healing with Melissa Afflerbach


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Are GLP-1 medications like semaglutide the breakthrough answer to weight loss—or just another overhyped trend?

In this special in-person episode of the Modern Thyroid and Wellness podcast, host McCall McPherson sits down with Melissa Afflerbach, Program Director at Modern Weight Loss, for an open, compassionate, and science-backed conversation about GLP-1 medications like semaglutide.

From debunking media myths to explaining microdosing and personalization, they explore the evolving role of these medications in treating metabolic dysfunction, inflammation, and chronic weight struggles. This episode offers support, clarity, and judgment-free education for anyone curious about GLP-1 therapy—whether for themselves or a loved one.

🔑 Key Topics Covered:
  • What GLP-1 medications are and how they actually work
  • Common myths debunked—from muscle loss to thyroid risks
  • Why microdosing and individualization are essential for long-term success
  • Clinical and personal stories of healing and improved quality of life
  • The ripple effects of improved metabolic health: reduced inflammation, better energy, mood, and mental freedom
  • Navigating side effects safely and responsibly
  • Understanding weight as a medical—not moral—issue
  • The emotional toll of shame and the power of empowered, informed decisions
  • Introduction to the Modern Weight Loss program: a data-driven, highly supportive approach tailored to real life

📲 Follow Modern Weight Loss:

💻 Website: https://modernweightloss.com/

📸 Instagram: https://www.instagram.com/modern_weight_loss/

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Modern Thyroid and WellnessBy McCall McPherson, PA-C

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