Ready to master the art of HRT? Join Nico's DAILY Newsletter for exclusive insights not found anywhere else: https://nicomislenp.kit.com/8050eeea5f

What if the standard approach to HRT dosing is setting your patients up for failure? Many clinicians make a critical mistake, assuming that replacing hormones is a simple one-to-one exchange. In episode 53 of the Nico Misleh Podcast, host Nico Misleh explains the essential principle that exogenous hormone replacement therapy does not act the same as the hormones our bodies produce naturally. This fundamental misunderstanding is why so many patients feel worse on testosterone replacement therapy and why "by-the-book" dosing often fails to resolve symptoms. Nico breaks down why higher doses are frequently needed, how TRT impacts other crucial hormones, and why a clinician's critical thinking is more valuable than just following lab values for achieving life-changing patient outcomes.

Discover the principles to prescribe with confidence and get superior results for your patients. Watch the full episode now, and if you are ready to become an expert in hormone optimization, enroll in The HRT Master Course today at: https://hrtuniversity.com/hrtcourse/⁠

For practitioners who want to confidently grow their practice with guidance in TRT, HRT, and business strategy, find us below:

- Nico's Daily Newsletter: ⁠⁠⁠https://nicomislenp.kit.com/8050eeea5f⁠⁠⁠ (yes, it's daily... and yes, people stay subscribed)

- Join HRT University: ⁠https://hrtuniversity.com/⁠

- Join the HRT University Facebook Group: ⁠⁠⁠https://www.facebook.com/groups/1179376819949373/?ref=share&_rdr⁠

Chapters:

0:00 - Why Most Clinicians Get HRT Wrong: A Core Principle 

1:42 - Is HRT Just "Algorithmic Medicine"? 

3:35 - Exogenous vs. Endogenous: The #1 HRT Rule You MUST Understand 

5:34 - The TRT Paradox: Does It Shut Down Your Natural Hormones? 

7:00 - Why "Natural" TRT Doses Make Men Feel WORSE 

9:52 - The Hidden Hormones You Lose on TRT (And Why It Matters) 

11:12 - The Surprising Link Between LH, HCG, and Brain Health 

12:20 - Hormone Resistance: Is It Like Insulin Resistance? 

13:24 - How to Dose Progesterone for a Young Female Patient 

14:24 - Is It The Dose or The Symptom? A Guide to HRT Priorities 

16:16 - Why Two People on the Same Insulin Dose Get Different Results 

18:20 - Is the Human Body a Computer? (Complex vs. Complicated Systems) 

21:04 - How Your Gut Microbiome Controls Your Health 

24:32 - How to Find Joy and Inspiration in Clinical Practice 

26:20 - A Professor's Secret to Understanding a "Boring" Subject 

30:04 - The Beautiful Language of the Universe 

32:40 - The BEST Resource to learn more about HRT