July 18, 2025

663: From Wired and Tired to Calm and Energized: The GABA-Mitochondria Connection + How to Fix It at the Cellular Level with Dr. Scott Sherr

59 minutes

Ever feel wired… yet exhausted? Or anxious… yet depleted?

In this episode, I’m sitting down with Dr. Scott Sherr, a visionary physician and expert in cutting-edge mitochondrial and nervous system healing, and he unpacks why so many women in midlife feel overstimulated and underpowered at the same time.

We dive into the role of GABA, the calming neurotransmitter your body craves, and why it’s often depleted during midlife, contributing to the anxiety, insomnia, and mood dips that leave you feeling unlike yourself.

Dr. Sherr also explains how mitochondrial dysfunction silently sabotages your energy, sleep, and even your joy—and what you can do to restore it naturally and effectively.

This conversation is packed with practical, science-backed strategies to help you step out of the cycle of stress and burnout and into a state of calm, clear, vibrant energy.

Ready to reclaim your vitality at every age? This podcast is for you!

Dr. Schott Sherr

Dr. Scott Sherr is a Board Certified Internal Medicine Physician Certified to Practice Health Optimization Medicine (HOMe) and a Hyperbaric Oxygen Therapy (HBOT) specialist. He’s the COO of Troscriptions, which offers formulations for optimal energy, focus, sleep, and stress support. He’s also the VP of Health Optimization Medicine and Practice (HOMe/HOPe), the nonprofit arm of Troscriptions, which trains practitioners on optimizing health rather than treating disease.

IN THIS EPISODE

The biggest factors that shift our metabolic energy

What is GABA, and why does it help balance our nervous system?

Natural ways to support the GABA system

Supplementation to support the GABA system

How to support healing and enhance mitochondrial function

How methylene blue helps support mitochondrial function

About Dr. Scott’s nonprofit: Health Optimization Medicine (HOMe)

QUOTES

“A big thing I've seen recently is tons of anxiety, tons of insomnia, tons of depression related to this inability to calm down, to turn our brains off. And some of those hormones that are transitioning as you go through the perimenopausal state are a big part of this.”

If we really want to focus on holistically improving your sleep, relationships, and energy, the primary focus needs to be downregulating your sympathetic nervous system and increasing your parasympathetic with the GABA enhancement aspect.”

“That's a really cool way of holistically enhancing the GABA system without causing GABA depletion or GABA deficiency on its own.”

RESOURCES MENTIONED

Troscriptions: use code ENERGIZED for 10% off all things in the store!

Home Hope Org

Dr. Scott Sherr’s Website

Dr. Scott’s Instagram

Preorder The Perimenopause Revolution HERE

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By Dr. Mariza Snyder

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