Astronomers have captured the first image of Sagittarius A*, the gargantuan black hole at the centre of our galaxy. Dr Ziri Younsi, University College London, shares what it took to capture a picture of a supermassive black hole that is 26,000 light-years away and from which (almost) nothing, not even light, can escape.

The world’s largest and most powerful particle accelerator, the Large Hadron Collider, is restarting after three years of upgrades. Roland Pease visits the European Particle Physics Laboratory, CERN, to see how things are going, and looks back on some of the team's past successes.

Also, how do you investigate the mysterious deaths of the world’s biggest fish when their bodies sink without trace? That’s the quandary facing marine scientists who’ve been trying to figure out what exactly is killing whale sharks. Freya Womersley, UK Marine Biological Association, shares how satellite tracking technology is helping us solve the mystery.

And finally, what’s in a name? As our inventory of Earth’s biodiversity progresses, the number of species given a Latin name is also growing. So, where do scientists find their naming inspiration? In Royal Society Proceedings B this week, an analysis of nearly 3,000 parasitic worm species uncovered some intriguing patterns and worrying biases. Samara Linton reports.

Presenter Victoria Gill

Produced by Alex Mansfield and Samara Linton

With the cost of living spiralling, many are probably thinking more about the price of food than lithium, titanium, copper or platinum. But the volatility in the global market for these materials - partly because of the pandemic and geopolitical unrest - is causing 'chaos' in the technology supply chain. Elizabeth Ratcliffe, Royal Society of Chemistry, tells Vic that many of us are unwittingly stockpiling these precious metals in our homes, in our old phones and defunct computers, because we don't know what to do with them. Reporter Samara Linton visits N2S, a company in Bury St Edmunds which has found a way to recycle the precious metals and other scarce elements in discarded circuit boards using bacteria.

This week more evidence that spring is springing earlier, as Vic heads to what might be the most studied woodland in the world: Wytham Woods in Oxfordshire. Ella Cole, Oxford University, explains how climate change is causing birds to lay eggs three weeks earlier than they did in the 1940s. And Chris Perrins, of Oxford University, shares his thoughts on the changing woodland.

And from new life to the very stuff of life. Could the building blocks of DNA have first been delivered to earth on a meteorite? In a paper in Nature Communications, scientists announce the discovery of the last two of the five key nucleobases locked in meteorites dating to the formation of the solar system. Samples of the Murchison Meteorite, a specific type of soft, loamy rock (CM2 carbonaceous chondrite) that fell to earth in 1969, have been re-examined, and the confirmation extends the ongoing debate around the nature and composition of terrestrial life's original crucible. Sara Russell, Professor of Planetary Sciences at London's Natural History Museum, helps Vic unravel the complicated and surprisingly controversial history of space rocks and primordial soup.

Presented by Vic Gill

Producer: Alex Mansfield

This week, we begin with a disturbing medical mystery. Since the start of the year, almost 200 children worldwide have fallen ill with hepatitis—or liver inflammation—without any apparent cause. Most of the children are under five, and nearly half of the cases were in the UK. Vic Gill asks clinical epidemiologist Deepti Gurdasani, Queen Mary University of London, what we do and don't know about these rare cases.

Also on the programme, with a huge tidal range, Wales and the west coast of England have become the focal point for a new generation of tidal power plans. So, is the tidal energy revolution finally happening? Roger Falconer, Emeritus Professor of Water and Environmental Engineering at Cardiff University, and Andrew Scott, CEO of Orbital Marine Power, which has demonstrated a working tidal stream turbine - called O2 - off Orkney, share their insights.

And fancy eating an insect burger? Or how about adding seaweed smoothies or mycoprotein meatballs to your diet? Fellow BBC science correspondent Helen Briggs shares how lab-grown proteins could make our diets much kinder to the planet.

And a recent study has found that a fifth of reptile species are at risk of extinction. Conservation scientist and study co-author Monika Bohm, Indianapolis Zoo in the US, tells us how, despite the gloomy findings, she remains hopeful.

Presented by Victoria Gill

Victoria Gill and guests ask why does scientific communication matters in society and how it might be done better, with Sam Illingworth, Berry Billingsley and Ozmala Ismail.

The climate crisis and Covid-19 have shown over the recent years the importance of reliable, relatable, transparent and trusted science communication. But just like science itself, it comes in different forms and takes different approaches. Always keen to keep you up to date, BBC Inside Science takes a moment to discuss good practice and how it might be done better.

Dr Oz Ismail is a dementia researcher who also finds time to do stand-up, public engagement and a podcast called Why Aren’t You A Doctor Yet?

Sam Illingworth is an Associate Professor at Edinburgh Napier University who investigates science and communication between disciplines. He is also a poet and writer, and has a podcast called The Poetry of Science.

And Berry Billingsley is Professor in Science Education at Canterbury Christchurch University. Erstwhile science broadcaster, she looks at ways science education could be enhanced through building what her team call Epistemic Insight - transforming the nature of science education in society's younger members.

Presented by Victoria Gill

Produced by Alex Mansfield and Samara Linton

Could magic mushrooms be the key to a revolution in treating depression? Professor David Nutt, director of the Imperial Centre for Psychedelic Research, thinks so. He tells Vic Gill about recent research suggesting that psilocybin - the psychedelic compound found in magic mushrooms - triggers rewiring of the brain in people with treatment-resistant depression. Vic Gill speaks with trial participant Steve Shorney who was diagnosed with depression 30 years ago.

Nanobodies. That's the name scientists have given to the tiny antibodies found in the blood of camelids like llamas, alpacas and camels. Reporter Samara Linton heads to Berkshire to meet the llamas whose nanobodies were recently found to neutralise the Covid-19 virus. We hear from Professor Gary Stephens, University of Reading, who is responsible for the llamas' safety and well-being, and Professor James Naismith, director of the Rosalind Franklin Institute which is carrying out the pioneering research with engineered nanobodies.

And just as the James Webb Space Telescope is poised to peer deep into the universe, we look at a recent image captured by its great predecessor, Hubble, which has thrown down a telescopic gauntlet. Astronomer Dr Emma Chapman, author of the book “First Light” guides us through these incredible pictures of the furthest, faintest, most ancient of stars yet seen.

Presented by Victoria Gill

Covid-19 infections in the UK are at an all-time high. But most people in England can no longer access free Covid-19 tests, and the REACT-1 study, which has been testing more than 100,000 individuals since the pandemic began, ended last week after its funding stopped. Martin Mckee, Prof of European Health at the London School of Hygiene and Tropical Medicine, shares his insights on what these changes might mean for ambitions to 'live with the virus'.

This week, the UN's latest Intergovernmental Panel on Climate Change (IPCC) report has unveiled a to-do list of ways to save the planet from climate catastrophe. How do scientists reach a global consensus on climate change amid war, an energy crisis, and a pandemic? Vic Gill speaks to report co-author Jo House, University of Bristol, and Ukrainian climate scientist Svitlana Krakovska who took part in signing off every line of the report while sheltering from the war in Kyiv.

And from our planet's present and future to its ancient past. Scientists working on the Tanis fossil site in North Dakota in the US have dug up a dinosaur's leg, complete with skin and scales. Is this 66-million-year-old fossil, alongside similar nearby victims, the key to unveiling those transformative minutes after the infamous Chicxulub asteroid struck the earth and ended the era of the dinosaurs? BBC science correspondent Jonathan Amos has seen the fossil and speaks with Paul Barrett of London's Natural History Museum about the significance of this un-reviewed new finds.

And from earth to Mars. After a year of analysing audio recordings from NASA's Perseverance rover, scientists have found not one but two speeds of sound on Mars. Trevor Cox, Professor of Acoustic Engineering at the University of Salford, guides us through this sonic wonder, and how sound may become a key tool for exploring distant worlds.

Mars audio credit: NASA/JPL-Caltech/LANL/CNES/CNRS/ISAE-Supaéro

Energy is essential: every living thing needs energy to survive, and today’s industrialised societies consume enormous quantities of it. At the moment, the vast majority of this comes from burning fossil fuels that emit carbon. But the government is committed to reaching net zero carbon emissions by 2050. Meanwhile, oil and gas prices are rocketing, exacerbated by the ongoing war in Ukraine. And the energy price cap is being raised on April 1st, hitting millions of householders in the UK.

While we await the government’s energy strategy, Inside Science looks at how to solve the problem, finding the best possible ways to meet our energy needs while slashing our carbon emissions. Joining us to discuss this are Alice Bell, co-director of the climate charity Possible, and Jan Rosenow, director at the Regulatory Assistance Project.

We also hear from Chris Stark of the Climate Change Commission on how the government might meet its decarbonisation targets, visit a Cornish field that might be a rich source of homegrown lithium for batteries, and talk to Jonathan Atkinson from People Powered Retrofit about how to make our homes greener and warmer.

This month the Royal Society of Chemistry released a shocking report on racial inequality at all stages of academia, from research funding to career progression. Black scientists in particular are unfairly disadvantaged when it comes to funding allocation. This is bad for them, bad for science, and bad for society. So how do we change things? Dr Diego Baptista from the Wellcome Trust, Professor Melanie Welham from the UKRI, and Dr Addy Adelaine, from the non-profit organisation Ladders4Action, join us to discuss the issue.

Both of Earth’s poles were hit by heatwaves this week. The Arctic was 30 degrees above average for this time of year, and the Antarctic was an unprecedented 40 degrees above average. We are seeing more extreme temperatures everywhere on earth, but for both poles to experience such heatwaves at the same time is highly unusual. Ed Blockley of the Met Office’s Polar Climate Group explains what’s going on.

One of the simplest ways to improve your local environment is to plant a hedge, which not only helps wildlife but can reduce flooding and pollution. But what kind of hedge should you plant? Scientists at the University of Reading and the Royal Horticultural Society are beginning a two year experiment to see which combinations of hedges bring the most benefits. Dr Tijana Blanusa tells us why planting hedges and generally greening our gardens is so important in the current climate.

Presented by Gaia Vince

The Russian conflict in Ukraine is already causing hunger there, and as Ukraine and Russia are huge grain exporters, the crisis will be far reaching. Food prices everywhere are expected to rise, and there’s fear that the war could affect food supplies in some of the poorest parts of the world. Tim Lang, Emeritus Professor of Food Policy at City University of London, and Dr Hannah Ritchie, Head of Research at the website Our World in Data, join us to discuss food security.

Lead is highly toxic to humans and other animals. One source of lead in the environment is the bullets and shot used to hunt wild game, and new research shows that lead shot has a significant effect on birds of prey such as eagles, buzzards and vultures across the whole of Europe. One of the study’s authors, Professor Debbie Pain, explains the research.

Many of us have spent the past two years anxiously following Covid graphs, but from next month the government is cutting funding to several surveillance programmes. Mass free testing will also end, though the Office for National Statistics survey will continue. Given that case numbers are rising, is reduced monitoring wise? Professor Adam Kucharski from the London School of Hygiene and Tropical Medicine discusses how important surveillance has been in the pandemic.

The last crewed mission to the Moon was half a century ago, and no one has made that one small step since. But a new NASA programme aims to change that, and tonight is the rollout of Artemis I, the first stage on a journey to return humans to the moon, including the first woman on the moon and the first person of colour on the moon. BBC science correspondent Jon Amos paints a picture of what we’ll see tonight.

The High Seas make up most of our oceans but belong to no-one and are largely unregulated, leaving them at risk of plunder. UN talks start afresh this week with the aim of protecting the marine biodiversity of these vast swathes of living ocean.

Covid-19 can shrink our brains and lead to cognitive decline, even in mild cases, according to a new study out this week. Professor Gwenaëlle Douaud, who led the research, explains how they used hundreds of brain scans to discover the effects of Covid infection.

A completely different discovery this week was made at the bottom of the sea; we hear how, after 107 years, scientists have finally found The Endurance, the lost shipwreck of Antarctic explorer Sir Ernest Shackleton.

How might the Russian invasion of Ukraine affect international space exploration? After a Twitter spat between a former NASA astronaut and the Russian space chief, we’re joined by BBC science correspondent Jonathan Amos and BBC Russian’s Nikolay Voronin to discuss how science in Russia and the rest of the world may be impacted by the current conflict.

And finally, the stunning discovery of a 330 million-year-old vampyropod fossil, the earliest known relative of modern-day octopuses and vampire squids, gives us an opportunity to imagine the world it inhabited, a third of a billion years ago.