How can we hack the human body to reach its full potential — and beyond? Right now, we can't stop aging. However, we can slow it down by optimising our health to lead long and fulfilling lives. One day, we may even be able to age backwards. Through biohacking, we can use the latest medical research to our body's advantage.

Dave Asprey, the Father of Biohacking and longevity expert, joins us in this episode. Working with renowned doctors and scientists, Dave has created a solution to innovate and hack our systems to push the limits of what the human body can do. He also shares advice on fasting, longevity, and the measures he takes to live a long and healthy life.

If you want to learn more about biohacking to improve your health and well-being, then this episode is for you! You’ll find out what it takes to live a longer and more fulfilling life.

 

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Here are three reasons why you should listen to the full episode:

1. Learn how Dave Asprey started the biohacking movement.
2. Discover more about the science of fasting and how this can be beneficial for those who want to live longer.
3. Dave Asprey shares his takes on anti-aging research and the current state of the pharmaceutical industry.

 

 Resources 

• Gain exclusive access and bonuses to Pushing the Limits Podcast by becoming a patron! 
• Harness the power of NAD and NMN for anti-aging and longevity with NMN Bio. 
• Listen to other Pushing the Limits episodes:
• • #183: Sirtuins and NAD Supplements for Longevity with Dr Elena Seranova
  • #187: Back to Basics: Slow Down Ageing and Promote Longevity with Dr Elizabeth Yurth
  • #189: Understanding Autophagy and Increasing Your Longevity with Dr Elena Seranova
  • #196: Rethinking the Function of Mitochondria for Our Health with Dr Elizabeth Yurth
• Connect with Dave Asprey: Facebook | Twitter | Youtube |  Instagram |  LinkedIn | website
• Bulletproof
• • Bulletproof Coffee
• Bulletproof Radio
• • How to Live Your Life After Great Loss – Amanda Kloots with Dave Asprey
• Check out Dave’s books: 
• • Head Strong
  • The Better Baby Book
  • Fast This Way
  • The Bulletproof Diet
  • Super Human 
• Enrol for free: Dave Asprey 14-Day Sleep Challenge 
• Moldy documentary

 

Episode Highlights [05:15] Dave’s Journey to Becoming the Father of Biohacking 

• In his mid-20’s, Dave already exhibited the diseases of aging.
• He tried exercising and going on a diet to lose weight. However, Dave didn’t reap the results he wanted. 
• With his experience in Silicon Valley, Dave started to look at his body's systems as a hacker would.
• This change in perspective led to the birth of biohacking. Since then, he has shared his findings with the world through his programs, speaking engagements, products, and books.

[10:37] What Fasting Can Do For You

• For ten years, Dave worked with a community of people teaching intermittent fasting as part of the Bulletproof Diet.
• Autophagy is when the body cleans out old cells and old proteins. 
• You don't get the full effects of autophagy if you eat three meals a day or consume carbohydrates and sugars.
• There are different benefits to having periods where you go without eating food.
• Fasting is not about suffering; it’s about knowing how not to be hungry as you fast. 

[14:51] Biohacking Tips on Fasting

• Have black coffee in the morning. This drink amplifies your body's ability to make ketones.
• You can also choose to add grass-fed butter and MCT oil. The combination gives you more hunger suppressants. 
• Finally, you can add prebiotic fibre to your black coffee. It’s a fibre that doesn’t raise your insulin and blood sugar levels.
• As long as you don’t have any protein and carbs that raise insulin, your body remains in a fasted state.

[18:32] Fasting From All Sorts of Things 

• Fasting from oxygen, which is called ‘breathwork’, is a big part of biohacking. 
• We could choose to go without the things that are causing the biological effects we don’t want.
• Fasting is about what you're trying to achieve, like getting rid of harmful proteins in your body to bring in good nutrients.

[20:07] How to Deal with LPS

• When a living organism feels threatened, they react in three ways: fear, food, and fertility. You either run away, eat everything, or ensure the survival of your species.
• Fasting threatens your gut bacteria. In response to fasting, they secrete toxins called lipopolysaccharides (LPS) to keep the other bacteria from competing. 
• In response, your liver will ask for sugar to oxidise the LPS.
• Fasting can make your gut bacteria unhappy and cause cravings. Toxin binders like activated charcoal work incredibly well to counteract this effect.
• According to Dave, activated charcoals induces a 15% life extension in rats who take it regularly.

[23:30] On Supplements to Take When Fasting

• Your fat stores toxins. If you’re losing weight, you’re gaining toxins unless you bind them.
• Advanced supplements include senolytics and spermidine.

• Spermidine was not readily available before; it used to be a very expensive research chemical.
• Dave instead took probiotics from Japan that helped his body make spermidine.
• A chapter in Fast This Way has a list of safe, effective supplements to use during a fast.

[26:15] Fasting is Like Exercising

• While fasting, you need a certain amount of oxidative stress.
• If you were to remove all the stressors during a fast, you won't get the benefits of fasting.

[28:41] The Paradigm Shift in Our Medical System

• Dave traces back the problem to when the FTC allowed pharmaceutical companies to advertise in the US. 
• We're good at recognising short-term patterns but terrible at seeing long term consequences.
• Our reactions to COVID are exaggerated. In reality, the actual risk is much lower. 
• However, pharmaceutical companies amplify the risk because they make money from governments through the virus.
• We need to take the pharmaceutical companies away from the doctors.

[34:57] Being Vi-Curious

• Dave was not opposed to vaccines before the pandemic. He identifies himself as vi-curious, or vaccine industry curious.
• In Superhuman, Dave writes about the four big killers. He notes that he’s looking forward to getting well-tested vaccines for these diseases.
• Having this conversation about being preventative and optimising your health is necessary to understand how our biology works.
• There are some unknown risks to both the vaccines and the virus.

• Being vi-curious means you’re in the middle of those who are vaccine-promiscuous and anti-vaxxers. It’s where 90% of the people are.

[40:35] Doing Something We Don’t Want to Do

• We’re stiff-armed into doing things we don’t necessarily want to do.
• You don’t have to react with anxiety or fear. Instead, you can react with intelligence, logic, and thought.
• We have a long history of not having as much control as we want.
• Medical freedom is one of the most precious rights. It means you have a right to decide what you put into your body.

[42:00] Dave’s Take on Longevity  

• Dave believes that he can live until he’s 180. 
• If we don't destroy the planet, we can do 50% better than today because of all the constant advancements in technology and research. 
• We are cracking the core biology behind aging and our ability to replenish our systems.
• Sooner or later, technology that was once expensive will be more readily available. 
• Dave aims to show the effectiveness of these technologies. By increasing demand and supply, prices will drop.  

[47:11] Individuals Over 60 Tend to Be Happier

• When we're young, we worry about what everyone else is thinking about us.
• Then, when we’re middle-aged, we’re more concerned about what we think of others.
• However, when we're old, we realise people don't think about us as much. People who have enough energy and don't have medical problems at this age tend to be much happier.
• Dave hopes that we can go back to awake and powerful elders.
• The goal of the anti-aging community is to have people whose brains work like young people but have the wisdom of age. 

[49:15] How Dave Asprey Creates an Impact 

• For five years, Dave taught at the University of California and worked at the company that held Google’s first servers.
• Biology behaves very much like how the internet does. If you can hack a system, that means you can hack the human body.
• These experiences prepared Dave to start the biohacking movement. 
• If what you’re teaching is efficient and you keep sharing it, you can build a movement of your own. 
• Doing so takes a lot of time and energy, so it has to be worth it. In Dave’s case, it is.

 

7 Powerful Quotes

‘Fasting isn't a lack of energy going into the body. Fasting is going without. And the hallmarks of fasting are insulin doesn't go up. And your levels of something called mTOR don't go up.’

'Maybe you're in the middle. In fact, I will tell you right now, 90% of people are in the middle. And it's the angry people who yell at the extreme anti-vax and the extreme vaccine promiscuous side — they're bullies.'

‘You're already stiff-armed into doing all sorts of stuff you don't want to do it. But you don't have to react with anxiety or fear. You can react with intelligence, and logic, and thought.’

‘Medical freedom is one of the most precious rights. That means you have a right to choose what you put into your body and what you don't put in your body from a food perspective, from a supplements perspective, and from a pharmaceutical perspective.’

‘We are cracking the core biology behind aging and our ability to replenish and repair and rejuvenate our systems. So it's your job: age a little bit less quickly, prepare yourself a little bit better. Every year, the technology gets better and better.’

‘People who have enough energy and don't have medical problems as they age tend to be much happier because they've learned the skill of being happy. It turns out we can teach our younger people that, and the way we've always done that is through coming-of-age rituals.’

‘The more successful you are, the more the crazy 5% sociopaths and psychopaths yell and scream and complain online.’

 

About Dave

Dave Asprey is an entrepreneur, author, host of Bulletproof Radio, and founder of Bulletproof. He is widely known as the Father of Biohacking. Over the last 20 years, Dave has worked with numerous medical and scientific experts to uncover and develop innovative methods to push the potentials of the human body. Through this, he has created the Bulletproof Diet and innovated Bulletproof Coffee and other wellness products. 

Dave has also written extensively on his experiences with biohacking technologies and research. He’s a four-time New York Times best-selling author. His mission is to empower individuals worldwide on the techniques of biohacking to lead long and fulfilling lives.

You can reach Dave on Facebook, Twitter, Youtube, Instagram, and LinkedIn. You can also check out his website and Bulletproof to know more about him and his work.

 

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To pushing the limits,

Lisa

The information contained in this show is not medical advice it is for educational purposes only and the opinions of guests are not the views of the show. Please seed your own medical advice from a registered medical professional.