The ASPREE study was a trial of aspirin in 20,000 healthy adults, age 70 and older. It was published in September 2018 in the New England Journal of Medicine.

This podcast covers the Nature magazine article on the impact of AGE (Aged Garlic Extract) on the inflammatory response triggered by Lipo-polysaccharide. According to the authors, it decreased 2/3 of the inflammatory mRNA gene expression.

ACCORD was a large (over 10,000 subjects, 71 centers) trial of lower A1c levels in people with advanced diabetes and pre-existing cardiovascular disease. Over 32% were already on insulin; their mean BMIs were over 30.

You can actually estimate arterial age using ultrasound technology of the arterial wall. Carotid intima-media thickness (CIMT) measurement allows estimation of arterial age.

This podcast explains and balances the risks and benefits of statin use. There are risks from myopathy (muscle tissue breakdown), the advancement of diabetes, and even a potential risk of stroke.

Most doctors prescribe statins to lower LDL (or "bad" cholesterol). However, that's probably not how statins prevent heart attacks and strokes. It's more likely due to an impact on cardiovascular inflammation.

Livalo (pitavastatin) is a newcomer to the statin market. It brings many advantages with improvements in LDL, HDL, muscle damage side effects, and even glucose/HgA1c values.

So why have I not given it over Crestor (rosuvastatin)?

Continuous glucose monitoring has many advantages over conventional glucometers that incorporate lances and testing strips. Just how accurate are these new continuous devices and how reliable is the information we obtain from them?

One study found out that patients with HIIT training had fewer episodes of atrial fibrillation. Also, the episodes were shorter and less intense.

Elliott and others were asked to do this editorial because of their own work in the area. They review the importance of atrial fib and the importance of exercise in the prevention of atrial fibrillation.