There are plenty of studies showing that chemicals found in the environment can directly impact human health. Some new research finds that certain environmental compounds may trigger early female puberty. Joining host Aaron Lohr to talk about that research is Natalie Shaw, MD, a Lasker clinical research scholar and principal investigator of the pediatric neuroendocrinology group in the Clinical Research Branch of the National Institute of Environmental Health Sciences. Dr. Shaw and colleagues authored an article recently published in the journal Endocrinology titled, “Identification of Environmental Compounds That May Trigger Early Female Puberty by Activating Human GnRHR and KISS1R.” Show notes are available at https://www.endocrine.org/podcast/enp95-environmental-impact-on-early-female-puberty — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

It’s been a few years, but we are here with an update on acromegaly, covering prevalence, diagnosis, traditional treatment, new therapies, and current gaps in understanding. Host Aaron Lohr talks again with Maria Fleseriu, MD, professor of medicine and professor of neurological surgery at Oregon Health & Science University School of Medicine and director of OHSU’s Pituitary Center. Dr. Fleseriu also serves on the Board of Directors of the Endocrine Society. Show notes are available at https://www.endocrine.org/podcast/enp94-update-on-acromegaly — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Host Aaron Lohr talks with Rita Kalyani, MD, professor of medicine at Johns Hopkins University School of Medicine and president-elect of medicine and science at the American Diabetes Association. Earlier this year, Dr. Kalyani and colleagues published a position statement in The Journal of Clinical Endocrinology & Metabolism titled, “Prioritizing Patient Experiences in the Management of Diabetes and Its Complications: An Endocrine Society Position Statement.” Show notes are available at https://www.endocrine.org/podcast/enp93-patience-experience-in-managing-diabetes — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

In this episode, we talk about pheochromocytomas. Host Aaron Lohr talks with Nikhitha Chandrashekar, MD, who recently finished her endocrinology fellowship at University Hospitals Case Western Reserve University in Cleveland. Dr. Chandrashekar presented a case study on pheochromocytomas at ENDO 2024. Show notes are available at https://www.endocrine.org/podcast/enp92-pheochromocytomas — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Our bodies typically do a remarkable job of recovering from certain injuries, and thyroid hormone signaling has an essential role to play there. But what is that process like for someone with hypothyroidism, and is there a unique role in that process for muscle stem cells? Host Aaron Lohr talks with Paola Aguiari, PhD, a senior research specialist at Children’s Hospital Los Angeles. She presented an abstract at ENDO 2024 titled, “Hypothyroidism Impairs Skeletal Muscle Regeneration After Injury.” Show notes are available at https://www.endocrine.org/podcast/enp91-hypothyroidism-and-muscle-regeneration — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

We all know that stress leads to a number of negative outcomes. In this episode, we talk about how early life stress may influence youth substance use initiation and some endocrine factors that may be helping to drive that influence. Host Aaron Lohr talks with Alexandra M. Donovan, PhD, of the Charles R. Drew University of Medicine and Science. Dr. Donovan recently presented an abstract at ENDO 2024 titled, “Early Life Stress and Pubertal Predictors of Youth Substance Use Initiation: Does Sex Moderate the Relationship Between Early Life Stress, Puberty, and Substance Use Initiation?” Show notes are available at https://www.endocrine.org/podcast/enp90-early-life-stress-and-substance-use — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

In this episode, we talk about brown fat and some new discoveries in how it regulates metabolic function. Joining host Aaron Lohr is Marsel Lino, PhD, a research fellow at Joslin Diabetes Center in Boston. Dr. Lino presented an abstract at ENDO 2024 titled, “A New Layer of Endocrine Regulation: Brown Fat Secretes Exosomal MicroRNAs, Which Regulate Metabolic Functions and Distal Organs.” Show notes are available at https://www.endocrine.org/podcast/enp89-brown-fat-and-metabolic-function — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Many people take over-the-counter supplements for a variety of reasons, but it isn’t always clear what’s in those supplements. And while they may be intended to help, some may cause harm. In this episode, host Aaron Lohr talks with Kevin Wei, MD, from the University of Southern California/Los Angeles General Medical Center Internal Medicine Residency Program about the presence of glucocorticoids in some over-the counter supplements and why that may be a concern. Dr. Wei and colleagues presented an abstract at ENDO 2024 titled, “Characterizing the Physiological Side Effects of Over-the-Counter Arthritis Supplements.” Show notes are available at https://www.endocrine.org/podcast/enp88-glucocorticoids-in-supplements — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

For those of us who try to lose weight at some point in time, we know the frustration of losing weight and feeling good about that, only to see that weight return. Why does that happen? Is the process the same for adults and adolescents? Is there any way to mitigate that weight regain? Joining host Aaron Lohr is Eric Bomberg, MD, assistant professor at the Center for Pediatric Obesity Medicine at the University of Minnesota. Dr. Bomberg recently presented an abstract at ENDO 2024 titled, “Hormonal and Physiological Changes Following Short-Term Weight Loss in Adolescents With Obesity and the Role of Glucagon-Like Peptide 1 Receptor Agonist to Counteract Adaptations.” Show notes are available at https://www.endocrine.org/podcast/enp87-short-term-weight-loss-in-adolescents-with-obesity — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast