In this episode, Drs Eric Trexler and Lauren Colenso-Semple critically analyze a recent narrative review on menopause and metabolism, discussing the nuances of scientific research, methodology, and how findings are communicated in the media. They explore the complexities of measuring energy expenditure, the limitations of rodent models, and the importance of interpreting scientific data effectively and responsibly.

Chapters

00:00 Chatter and introducing new review paper

06:22 Social media claims about the paper

08:15 What is a "narrative review"

14:03 Nuances of metabolism research

20:03 Fat Oxidation versus fat loss

24:00 Claims versus data (resting expenditure)

31:06 Effects of hormone therapy & Limitations of Rodent Studies

36:05 Summarizing resting metabolism data

39:49 Claims versus data (activity expenditure)

43:34 Re-interpreting the data

45:20 Advice for assessing evidence behind claims

51:56 Conclusions and future directions

55:54 How this relates (or doesn't) to "calories in, calories out"

59:47 Wrapping up the show