The Pound of Cure Weight Loss Podcast

Episode 69: GLP-1 Medications, Muscle Loss, and Strength Training: What the Science Really Says


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In this episode of the Pound of Cure Weight Loss Podcast, Dr. Matthew Weiner and registered dietitian Zoë dive deep into the latest research on GLP-1 medications and their evolving role in weight loss, muscle preservation, and even potential cancer treatment.

They break down what the newest studies actually show — including why so many headlines are misleading, and how to interpret scientific research through a more critical lens.

You’ll also learn why strength training is non-negotiable during GLP-1 therapy or bariatric weight loss, what to know about oral semaglutide vs. injectable versions, and how nutrition plays a key role in maintaining muscle mass while losing weight.

Whether you're a patient on Ozempic, Wegovy, Zepbound, or considering medication as part of your obesity treatment, this episode helps you make more informed, science-based decisions.

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The Pound of Cure Weight Loss PodcastBy Matthew Weiner, MD and Zoe Schroeder, RD

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