The Fasting Method Podcast

Fasting Q&A with Dr Jason Fung: Off-Label Use of GLP-1s, Double Diabetes, Seed Oils, and More.


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Episode #206

In this Fasting Q&A episode, hosted by Coach Lisa Chance, Dr. Jason Fung answers questions from the TFM Community:

  1. Are there common strategies that help to avoid the common pitfalls of Ramadan, like late night eating, overeating, or accidentally doing OMAD for too long and slowing down the metabolic rate? [01:07]
  2. Concerns about off-label use of GLP-1s. Some medical professionals seem to be prescribing GLP-1 medications for anti-aging/longevity purposes in people who aren't overweight or diabetic. What do you think about the trend of “microdosing” GLP-1s as a preventative health measure? [02:36]
  3. Are there further short and long-term side effects of GLP-1s coming to light? [06:36]
  4. Are there ethical concerns around supply issues with GLP-1s due to increased demand from off-label use? [ 10:12]
  5. Are there bioethical concerns about GLP-1s that doctors should be discussing with patients? [12:03]
  6. Can you address how people with Type 1 diabetes can develop insulin resistance similar to those with Type 2, sometimes referred to as ‘double diabetes’? [16:21]
  7. How concerning is an elevated Lp(a) and how can you lower it? [20:47]
  8. Do you know of research or trials with fasting to reduce prostate size?  [26:28]
  9. Can someone who is considering kidney donation fast/fat fast? [29:08]
  10. I'm seeing many reputable sources saying that the claims against seed oils aren't actually based in the science. I'm curious whether Dr. Fung's opinion has evolved on this? [30:51]

 

Links

A Conversation with Dr. Tro Kalayjian 

https://youtu.be/2Vuhip2UlTs?si=fxHBpgNkcI65SOrV

Cholesterol Ration Calculator - Omni Calculator

https://www.omnicalculator.com/health/cholesterol-ratio 

 

Please note that you need to be a member of the TFM Community to submit questions to the Q&A webinars with Dr. Fung but you can submit questions to our regular Q&A episodes here: https://bit.ly/TFMPodcastQs

 

Transcripts of all episodes are available on the Podcast page at www.thefastingmethod.com

 

Sign Up to the How to Fat Fast Masterclass with Dr. Nadia Pateguana here:

https://www.thefastingmethod.com/masterclasses-and-live-workshops-2025/#FFMC

Discount Code - PODCAST10

 

Explore the TFM Community with a 7-Day FREE TRIAL

https://www.thefastingmethod.com/community/

 

Book a complimentary 15-minute coaching intake assessment with one of the TFM coaches

https://www.thefastingmethod.com/coaching/

 

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Join our FREE Facebook Group: https://bit.ly/TFMNetwork

 

Summary Timestamps

00:00 Intro

01:07 Fasting Strategies for Ramadan

02:36 GLP-1s for Off-Label Use

06:36 Side Effects of GLP-1s

10:12 Ethical Concerns with GLP-1 Supply Issues

12:03 Bioethical Concerns GLP-1s

16:21 Type 1 Diabetes and IR

20:47 Lp(a)

29:08 Kidney Donation and Fasting

30:51 Seed Oils

 

 

Disclaimer

This podcast is for educational purposes only and is not a substitute for professional care by a doctor or other qualified medical professional. You should always speak with your physician or other healthcare professional before doing any fasting, changing your diet, taking or adjusting any medication or supplements, or adopting any treatment for a health problem. The use of any other products or services purchased by you as a result of this podcast does not create a healthcare provider-patient relationship between you and any of the experts affiliated with this podcast. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

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