Health Longevity Secrets

#017 - Everyone knows that sugar is unhealthy but how dangerous is it really?

Dr. Michael Goran is the bestselling co-author of the book: Sugarproof: The Hidden Dangers of Sugar That Are Putting Your Child's Health at Risk and What You Can Do.

He is a Professor of Pediatrics in the Keck School of Medicine at the University of Southern California.  Dr. Goran  serves as Co-Director of the USC Diabetes and Obesity Research Institute. He received his Ph.D. from the University of Manchester, UK.

Dr. Goran’s research has focused on the causes and consequences of childhood obesity for over 30 years. He has published over 350 professional peer-reviewed articles and reviews.

https://sugarproofkids.com/michael-goran/

 #sugar #wellness  #children #lifestylemedicine #younger #michaelgoran #RobertLufkinMD #readouthealth #sugarproof

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Robert Lufkin MD may at any time and at its sole discretion change or replace the information available on this channel. To the extent permitted by mandatory law, Robert Lufkin MD shall not be liable for any direct, incidental, consequential, indirect or punitive damages arising out of access to or use of any content available on this channel, including viruses, regardless of the accuracy or completeness of any such content.

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#016- There is no FDA approved drug that will reduce the symptoms of Alzheimer’s disease. The most they promise is to slow its progression. Could there be an antidote to Alzheimer’s disease right in front of us that most people do not recognize?

Our guest is Amy Berger, MS, CNS. She is a Certified Nutrition Specialist who specializes in using low-carb and ketogenic nutrition to help people reclaim their vitality. 

Amy is an international speaker, has authored peer-reviewed journal articles, and serves on the review committee for the Certification Examination for Nutrition Specialists. She has published the book The Alzheimer’s Antidote: Using a Low-Carb, High-Fat Diet to Fight Alzheimer’s Disease, Memory Loss, and Cognitive Decline.

Amy has a bachelor’s degree from Carnegie Mellon University and a Master’s in human nutrition from the University of Bridgeport. She has been eating a low-carb diet and maintaining a 35-pound weight loss for over 15 years. Amy loves using both her writing and nutrition backgrounds to help other people learn about low-carb and keto nutrition.

www.tuitnutrition.com

 #longevity #wellness  #Ketones #lifestylemedicine #younger #ketosis #biohacking #acetone #RobertLufkinMD #readouthealth #alzheimers #amyberger #alzheimersantidote #tuitnutrition

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NOTE: This is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have. Never disregard professional medical advice or delay in seeking it because of something you have seen here. 

Robert Lufkin MD may at any time and at its sole discretion change or replace the information available on this channel. To the extent permitted by mandatory law, Robert Lufkin MD shall not be liable for any direct, incidental, consequential, indirect or punitive damages arising out of access to or use of any content available on this channel, including viruses, regardless of the accuracy or completeness of any such content.

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#015-What is the best way to detect ketosis?

Ketones and ketosis are everywhere in the news. What are ketone bodies?

Why are they good for us? How do we measure them? 
 Our guest today is Jim Howard, the CEO of biomarker-based startup 

Readout Health. Their product  Biosense is the first clinical-grade, handheld 

device that measures nutritional ketosis for chronic disease and 

longevity/wellness focused consumers. He is a digital health 

executive with an MBA from University of Missouri-Saint Louis.

Take away points:

Three Ketone bodies are produced as a by‐product of fat metabolism. When the liver metabolizes free fatty acids,  they are transformed into acetyl‐CoA, a molecule used in the production of energy. Depending on the glucose level, acetyl‐CoA can be diverted to  produce acetoacetate, the first of three ketone bodies.  Acetoacetate can further produce β‐hydroxybutyrate and acetone, by enzymatic degradation or spontaneous decarboxylation respectively.

All three ketone bodies circulate in the bloodstream. Acetone, because of its small size, diffuses into the lung and appears in the exhaled breath. The devices we will be discussing detect levels of acetone from this process.

Deep lung measurement.

Biosense Breath Ketone Monitor -Use the code Lufkin20 for a $20 discount at 
https://mybiosense.com/

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NOTE: This is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have. Never disregard professional medical advice or delay in seeking it because of something you have seen here. Robert Lufkin MD may at any time and at its sole discretion change or replace the information available on this channel. To the extent permitted by mandatory law, Robert Lufkin MD shall not be liable for any direct, incidental, consequential, indirect or punitive damages arising out of access to or use of any content available on this channel, including viruses, regardless of the accuracy or completeness of any such content.

Disclaimer: We are ambassadors or affiliates for many of the brands we reference on the channel.
 ————————————————————————
 #longevity #wellness #antiaging #Ketones #lifestylemedicine #younger #ketosis #biohacking #acetone #RobertLufkinMD #readouthealth #biosense #jimhoward

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#014- Today we discuss how a process called Keto-flexing can deliver metabolic health. 

Our guest is Ben Azadi, FDN-P who is on a mission to help 1 billion people live a healthier lifestyle. Ben is the author of several best-selling books- The Perfect Health Booklet, The Intermittent Fasting Cheat Sheet, The Power of Sleep, and most recently Keto Flex.  
Ben is the founder of Keto Kamp. He is the go-to source for intermittent fasting and the ketogenic diet. He is known as ‘The Health Detective’ because he investigates dysfunction, and educates, not medicates, to bring the body back to normal function.  

TAKE HOME POINTS:
Keto Flexing is a novel approach to ketogenic nutrition which involves ketosis, fasting, and flexible food choices to optimize the health value of this strategy. 

Ketosis is a normal state in our bodies that we do less and less of because of the American diet, which forces us into the glucose side. So returning to ketosis is not a fad or a particular diet, but it's a way of living. It has health advantages compared to when we burn glucose.  

For ketogenic diet we add fats and oils. It is best to avoid seed/vegetable oils. They are [3 C’s] canola oil, corn oil, cottonseed oil, [3 S’s] soybean oil, sunflower oil, safflower oil, and two others rice bran oil and grapeseed oil. They're very unstable and highly inflammatory. We prefer stable fats, saturated fats, monounsaturated fats such as coconut oil, real olive oil, avocado oil, butter, ghee, duck fat, and lard.  

https://www.benazadi.com/

https://www.youtube.com/channel/UCUh_MOM621MvpW_HLtfkLyQ

https://twitter.com/THEBENAZADI 

https://www.linkedin.com/in/ben-azadi-b7122323/ 

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  NOTE: This is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have. Never disregard professional medical advice or delay in seeking it because of something you have seen here. Robert Lufkin MD may at any time and at its sole discretion change or replace the information available on this channel. To the extent permitted by mandatory law, Robert Lufkin MD shall not be liable for any direct, incidental, consequential, indirect or punitive damages arising out of access to or use of any content available on this channel, including viruses, regardless of the accuracy or completeness of any such content.

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#ketoflex #wellness  #lifestylemedicine #benazadi  #biohacking #RobertLufkinMD  #ketokamp #ketosis #fasting #seedoils

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#013- I’m so sorry! A growing number of physicians have made open apologies for their past recommendations to their patients that encouraged low fat, high carbohydrate meals as a healthy lifestyle choice. 

I want to also add my sincere apologies to all my patients for the wrong advice that I have given over the years when I recommended a low fat diet and largely ignored the dangers of processed foods, seed oils, grains, and refined carbohydrates. 

The accumulated evidence is, in my opinion, overwhelmingly in support of the value of a low carbohydrate diet with limited processed foods, seed oils, and grains.  This is also ideally consumed in fairly narrow eating windows in order to decrease inflammation and insulin resistance while, maximizing metabolic flexibility and autophagy. 

Over the last few years there has been a revolution in our understanding of how major chronic diseases such as obesity, diabetes, hypertension, heart disease, stroke, dementia, and cancers are all linked by underlying longevity processes and most importantly that we can actually influence them through the choices we make in our lives and the primary choice that we can start with is correct diet- what we eat, when we eat, and how much we eat

The wonderful thing about science unlike say religion or politics is that with enough evidence we can all accept new ideas, and admit when we were wrong and change for the better.

As a result I have made this my primary focus to help bring quality evidence based information about health and longevity to the general public through social media, podcasts, video and other presentations such as this. 

I hope that you can join me on this exciting journey to transform our health and our lives!!

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 NOTE: This is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have. Never disregard professional medical advice or delay in seeking it because of something you have seen here. Robert Lufkin MD may at any time and at its sole discretion change or replace the information available on this channel. To the extent permitted by mandatory law, Robert Lufkin MD shall not be liable for any direct, incidental, consequential, indirect or punitive damages arising out of access to or use of any content available on this channel, including viruses, regardless of the accuracy or completeness of any such content.

Disclaimer: We are ambassadors or affiliates for many of the brands we reference on the channel. 
————————————————————————
#longevity #wellness  #lifestylemedicine #younger  #biohacking #RobertLufkinMD  #diet #lowcarb #heartdisease #cholesterol #LDL #HDL #triglycerides  

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#012-Our guest today is an expert in treating people with heart disease on the operating table who has begun to treat patients with a novel approach before they have a heart attack and arrive on his table. Eighty-eight percent of Americans are metabolically unhealthy -find out to change to lower that number.

Dr. Philip Ovadia is a cardiothoracic surgeon who also has a  practice focused on Metabolic Health and reducing Cardiac Risk.  He is the author of the book 'Stay Off My Operating Table.'

He completed a residency in General Surgery at the University of Medicine and Dentistry at New Jersey, and a Fellowship in Cardiothoracic Surgery at Tufts – New England Medical School.

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#011-Glycans are being hailed as possibly the next great biological longevity clock. Today we speak with the leading expert on the subject.  

Gordan Lauc PhD, is Professor of Biochemistry and Molecular biology at the University of Zagreb and Co-Founder and Chief Scientific Officer at GlycanAge. He graduated from the University of Zagreb Faculty of Science in 1992, and obtained PhD in Biochemistry and the University of Zagreb.

Take home points:

Glycans– the third revolution in evolution

Nuclei acids - 4 building blocks [linear]
Proteins -  20 amino acids [linear]
Glycoproteins- 2000+ [nonlinear]

Examples -Blood groups ABO are glycans

Post translational-make protein 

Glycans modifications of proteins lipids and even DNA by sugar

Nonlinear branching oligosaccharide 

    Glucose-monosaccharide-

Post translational modifications-

     Phosphorylation

     Glycosylation

AGE- advanced glycation end products——reaction glucose and proteins- not the same as glycosylation.

Immunoglobulins- older get more pro inflammatory glycans-

Igg glycosylation suppress inflammation

Human glycan project

Health Longevity Secrets show listeners who wish to try The Glyconage longevity clock on themselves can receive a 20% discount enter the code ROBERTLUFKIN at the glycanage.com website.

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NOTE: This is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have. Never disregard professional medical advice or delay in seeking it because of something you have seen here. Robert Lufkin MD may at any time and at its sole discretion change or replace the information available on this channel. To the extent permitted by mandatory law, Robert Lufkin MD shall not be liable for any direct, incidental, consequential, indirect or punitive damages arising out of access to or use of any content available on this channel, including viruses, regardless of the accuracy or completeness of any such content.

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#longevity #wellness #antiaging #MR #lifestylemedicine #younger #glycans #biohacking #RobertLufkinMD #genetics #glycosylation #gordonlauc

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#010-Today we take a look at gene therapy and the possibilities for longevity with someone who is not only an expert in the field but who has also tested the longevity gene therapy on herself. 
Elizabeth Parrish is an entrepreneur and founder and CEO of Bio-Viva Sciences. She is a graduate of the University of Washington. 

Preprint: Telomerase reverse transcriptase (TERT) and follistatin (FST). 
Mouse cytomegalovirus (MCMV) carrying exogenous TERT or FST (MCMVTERT or MCMVFST) extended median lifespan by 41.4% and 32.5%, respectively. First report of CMV being used successfully as both an intranasal and injectable gene therapy system to extend longevity. Jaijyan, Dabbu Kumar, Anca Selariu, Ruth Cruz-Cosme, Mingming Tong, Shaomin Yang, George Church, David Kekich, et al. “New Intranasal and Injectable Gene Therapy for Healthy Life Extension.” Preprint. Cell Biology, June 26, 2021. https://doi.org/10.1101/2021.06.26.449305.
https://www.biorxiv.org/content/10.1101/2021.06.26.449305v1.full.pdf 

https://bioviva-science.com/

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NOTE: This is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have. Never disregard professional medical advice or delay in seeking it because of something you have seen here. Robert Lufkin MD may at any time and at its sole discretion change or replace the information available on this channel. To the extent permitted by mandatory law, Robert Lufkin MD shall not be liable for any direct, incidental, consequential, indirect or punitive damages arising out of access to or use of any content available on this channel, including viruses, regardless of the accuracy or completeness of any such content.

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#longevity #wellness #antiaging #MR #lifestylemedicine #younger #artificial intelligence #biohacking #RobertLufkinMD

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#009-Ayruvedic medical traditions going back over 5000 years have a lot to say about approaches to preventing memory loss that have many fascinating similarities to the latest thinking about Alzheimer’s disease prevention.

Today we are joined by by someone who is not only an expert in the latest neuroscience and biochemistry of Alzheimer’s disease but is also an expert in Ayurveda.

Dr. Rammohan Rao is Principal Research Scientist at Apollo Health. He has a Ph.D. in neuroscience and biochemistry and has worked closely with Dr. Dale Bredesen at the Buck Institute for Research on Aging where he was an Associate Professor of Neuroscience focusing in the areas of chronic stress, neuronal cell death, and mechanisms of age-associated neurodegenerative diseases with special emphasis on Alzheimer’s disease.

Dr. Rao has over twenty-five years of research and teaching experience in neuroscience and has published more than 50 peer-reviewed papers in scientific journals and chapters in several textbooks.  He is also a National Ayurveda Medical Association (NAMA) board-certified Ayurveda Practitioner and a Registered Yoga Teacher (RYT-200) from Yoga Alliance USA and teaches Ayurveda and Yoga at the California College of Ayurveda.

Take home points:

-Ayurveda- Science of Life

-Network approach to disease rather than targeted drug approach

-Diet, herbs, aroma, lifestyle, yoga, meditation

-Mind and digestive system two main components

-Prevention strategies for memory loss

-AHARA- healthy diet- 12 hour overnight fast, no between meal snacks

-JATHARAGNI-Digestive fire

-NIDRA- sleep

-PANCHAKARMA- detoxification, purification, rejuvenation

-ABHYANGA-oil herb massage

-Herbs- Ashwagandha, Turmeric/Curcumin, gotu kola

-Brain exercises

-ACHARA-routines 

https://www.apollohealthco.com/apollo-health-welcomes-ram-rao-ph-d-as-our-principal-research-scientist/

https://www.ayushliving.com/united-states/concord/practitioners/dr-rammohan-rao

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#Ayurveda  #Alzheimer’s #dementia #memoryloss #lifestylemedicine #younger #RammohanRao #biohacking  #RobertLufkinMD

#009-Stress is now known to affect everything from gray hair to epigenetic age among other things in our health.  Dr Stephen Sideroff beautifully outlines the 9 pillars of resiliency that allow us to handle the inevitable chronic stress in our lives.

Please join Dr Stephen Sideroff for this masterclass in human stress management through building lasting resilience.

Take away points: 

-Stress can be both positive and negative. Chronic stress tends to be harmful.

 -Stress can affect telomeres and other markers for aging

-Early childhood experiences can strongly influence how we deal with stress as adults

03:38 Steve's early career in brain research

06:04 Failure of longterm results in stress management from single workshop

08:24 Early childhood experiences and the primitive gestalt effect on stress

14:23 Enhancing neuroplasticity

18:00 The path: mastering the nine pillars of resilience

24:12 Stress effect on telomeres and markers for aging

30:15 Concept of eustress for positive stress from Hans Selye

37:23 Key pillars of resilience

40:45 Relationship with ourselves, others, and something greater

41:52  John M. Gottman ratio of positive to negative couples interactions

45:03 Stress as sympathetic nervous system activator

48:21 Personal lifestyle choices

http://drstephensideroff.com/  

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NOTE: This is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have. Never disregard professional medical advice or delay in seeking it because of something you have seen here.

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#longevity  #wellness #antiaging #biologicalage #lifestylemedicine #younger #epigenetics #biohacking  #RobertLufkinMD #resilience #stephensideroff

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