>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<<

What if weight loss isn’t about discipline, motivation, or trying harder, but about understanding what your hormones are actually doing?

In this powerful New Year mash-up episode of Hormones, Metabolism, and You, Dr. Cassie Smith brings together the most impactful insights from three standout conversations to explain why traditional diets fail so many women and what truly supports sustainable weight loss.

Drawing from expert guidance by Tamar Samuels, Shana Hussin, and Terri DeNeui, this episode reframes weight gain as a hormonal and metabolic signal, not a personal failure.

Listeners will learn how stress, gut health, insulin resistance, PCOS, thyroid dysfunction, and age-related hormone shifts quietly sabotage fat loss, and why fasting, restriction, and one-size-fits-all diets often make things worse.

This episode is especially for women in their 30s, 40s, and 50s who feel stuck, exhausted, and frustrated despite doing “all the right things.”

Episode Highlights

Key Topics Covered

Final Takeaway

This New Year, the answer isn’t another diet, cleanse, or restriction plan.

Sustainable weight loss happens when you:

Your body isn’t broken. It’s communicating.

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What if your hormone symptoms aren’t a hormone problem at all, but warning signs of deeper toxic, gut, and immune stress your body has been carrying for years?

In this powerful episode of Hormones Metabolism in You, Dr. Cassie Smith sits down with Dr. Kelly K. McCann, MD, to unpack why hormone symptoms like fatigue, weight gain, brain fog, mood changes, and stubborn metabolic dysfunction are often not hormone problems at all.

Instead, Dr. McCann explains how these symptoms are signals pointing to deeper root causes such as environmental toxin exposure, mold, gut dysfunction, immune dysregulation, and chronic inflammation. Together, they challenge the conventional approach of treating hormones in isolation and highlight why normal lab results do not always mean the body is functioning optimally.

This conversation explores how everyday exposures from water contamination and plastics to non-stick cookware, pesticides, and personal care products can silently disrupt thyroid function, metabolism, and hormone signaling. The episode also dives into the critical gut hormone immune connection, mold related illness, nutrient depletion, mitochondrial dysfunction, and the concept of the cell danger response.

About the Guest

Dr. Kelly K. McCann, MD is a board certified physician trained in internal medicine and pediatrics, with advanced training in integrative and functional medicine. Her work focuses on the impact of environmental exposures on human health, including mold illness, chemical toxicity, chronic infections, immune dysregulation, and mast cell activation syndrome.

Dr. McCann specializes in treating complex chronic illness by addressing root causes such as toxic burden, gut permeability, mitochondrial dysfunction, and nervous system imbalance. She is the founder of The Spring Center in Southern California and provides care to patients across multiple states. She also teaches and writes extensively on the intersection of environment, immunity, hormones, and healing.

Key Topics Covered

Links & Resources: 

Dr. Kelly K. McCann, MD

🔗 Official Website
https://drkellymccann.com/

🔗 The Spring Center
https://thespringcenter.com/

🔗 LinkedIn Profile
https://www.linkedin.com/in/dr-kelly-mccann/

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What if many hormone, thyroid, and energy problems come down to a single overlooked molecule your body is quietly running out of?

In this episode of Hormones Metabolism in You, Dr. Cassie Smith sits down with nitric oxide expert Dr. Nathan Bryan to explore why nitric oxide is one of the most overlooked yet essential molecules in human health.

Together, they unpack nitric oxide’s powerful role in hormone signaling, thyroid function, gut motility, immune defense, blood flow, and mitochondrial energy production. Dr. Bryan explains how nitric oxide deficiency can contribute to fatigue, hormone resistance, insulin resistance, poor circulation, and chronic inflammation, even when labs appear “normal.”

They also discuss how modern lifestyle factors such as aging, chronic stress, poor diet, fluoride exposure, antiseptic mouthwash use, and long term antacid use can significantly impair nitric oxide production. Most importantly, this conversation offers practical, science backed strategies listeners can apply immediately to support nitric oxide levels and improve overall hormone health, energy, and longevity.

About the Guest

Dr. Nathan Bryan holds a Bachelor of Science in Biochemistry from the University of Texas at Austin and earned his doctoral degree from Louisiana State University School of Medicine in Shreveport, where he received the Dean’s Award for Excellence in Research. He completed postdoctoral training as a Kirschstein Fellow at Boston University School of Medicine in the Whitaker Cardiovascular Institute.

In 2006, Dr. Bryan joined the faculty at the University of Texas Health Science Center at Houston under the recruitment of Nobel Laureate Dr. Ferid Murad. With over two decades of experience in nitric oxide research, he has made significant contributions to the field, resulting in numerous US and international patents and clinically impactful technologies.

Dr. Bryan is also a successful entrepreneur and Founder and CEO of Nitric Oxide Innovations, LLC, where he continues to advance nitric oxide based therapies and molecular medicine worldwide.

Key Topics Covered

Links & Resources

Website: https://drnathansbryan.com/
LinkedIn: https://www.linkedin.com/in/drnathansbryan

Nitric Oxide Education:
https://www.n1o1.com/
https://www.no2u.com/
https://www.nitricoxideinnovations.com/

Shop N1O1 Products: https://www.awin1.com/cread.php?awinmid=115399&awinaffid=2702698

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What if the biggest problem in modern medicine isn’t a lack of treatments, but a lack of training in nutrition, gut health, and root cause care?

In this episode, Dr. Cassie Smith welcomes back Dr. Johnny Hadac, now a family medicine resident, to reflect on how his medical training has evolved and where traditional healthcare continues to fall short. Together, they unpack the realities of residency, the lack of meaningful nutrition and gut health education in medical training, and why chronic disease cannot be solved without addressing inflammation, hormones, and the gut.

Dr. Hadac shares what he has learned during his first months of residency, how functional medicine principles have shaped his approach to patient care, and why proactive, relationship based medicine leads to better outcomes. The conversation also explores the broken insurance driven healthcare system, the importance of provider education, and how social media can help close the knowledge gap.

They also dive into Dr. Hadac’s bestselling cookbook, which combines practical, affordable recipes with extensive education on gut health, insulin resistance, fiber, and hormone balance. This episode offers hope for the future of medicine and practical tools for patients and providers alike.

About the Guest

Dr. Johnny Hadac is a family medicine resident, physician, certified nutritionist, and culinary medicine specialist. He is the founder of Total Weight Loss and Muscle Dummies, a global health community with over two million followers focused on affordable, science based nutrition and lifestyle habits.

Dr. Hadac is a bestselling cookbook author and app developer who blends medical science with real world practicality. His work centers on gut health, insulin resistance, metabolic health, and sustainable weight loss through high fiber, high protein, whole food nutrition. Through social media, education, and clinical practice, he is helping reshape how people understand health, food, and disease prevention.

Key Topics Covered

Connect with Dr. Johnny Hadac

LinkedIn: https://www.linkedin.com/in/johnny-hadac-6a38aa126/
Instagram: https://www.instagram.com/drjohnnyhadac/

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➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<<

What if the biggest breakthrough in women’s health this decade is the long overdue reversal of a warning that never should have existed in the first place?

In this timely episode, Dr. Cassie Smith sits down with hormone expert and healthcare reform advocate Dr. Terri DeNeui, DNP, APRN, ACNP-BC to unpack the FDA’s landmark decision to remove the black box warning from estrogen containing HRT. For the first time in over twenty years, science and policy finally align, creating safer and more accessible options for millions of women.

Dr. Cassie and Dr. Terri break down what the original research actually showed, how estrogen became unfairly feared, and why the updated guidelines are long overdue. They explore the benefits of estrogen, progesterone, and testosterone for women, clearing up misconceptions and highlighting the need for better hormone education among providers and patients.

With clinical insights and decades of experience, this episode reveals the truth about hormone therapy, why women have suffered needlessly for two decades, and how the removal of the black box warning can reshape the future of women's health.

About the Guest

Dr. Terri DeNeui, DNP, APRN, ACNP-BC is a board certified Adult Acute Care Nurse Practitioner, entrepreneur, Chief Science Officer, and leading voice in healthcare reform. She serves on the Executive Committee of the America First Policy Institute and the America First Women’s Initiative, contributing to national healthcare policy.

A Summa Cum Laude graduate of the University of Texas at Arlington, Dr. DeNeui holds the Doctor of Nursing Practice degree. She is the Founder of EVEXIAS Medical Centers and EVEXIAS Health Solutions, and creator of the EvexiPEL Method of hormone optimization, used globally and supported by outcomes research. She is also lead teaching faculty for the A4M World Congress on Anti Aging Medicine.

Her published work includes the peer reviewed article Best Practices in Care for the Menopausal Patient and the bestselling book Hormone Havoc: Dispelling the Myths and Misconceptions about Hormones in Women and Men.

Key Topics Covered

Connect with Dr. Terri DeNeui

Instagram: https://www.instagram.com/drterrideneui/

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💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<<

What if the key to reversing Graves disease starts with uncovering the hidden triggers your thyroid has been reacting to all along?

In this information rich episode, Dr. Cassie Smith sits down with functional medicine practitioner and thyroid expert Dr. Eric Osansky to break down the realities of Graves disease and hyperthyroidism. They explore why diagnosis is often delayed, what truly drives autoimmune thyroid conditions, and how gut health, nutrient deficiencies, infections, stress, and environmental toxins all influence thyroid function. Dr. Osansky also shares his personal remission journey and offers practical guidance, testing recommendations, and natural treatment options.
 This episode is essential for anyone navigating Graves disease, hyperthyroidism, or persistent thyroid symptoms and searching for a root cause approach.

About the Guest

Dr. Eric Osansky is a functional medicine practitioner with more than 15 years of clinical experience in chiropractic care, nutrition, and autoimmune thyroid health. After reversing his own Graves disease in 2009, he dedicated his career to helping others heal naturally. He is the author of Natural Treatment Solutions for Hyperthyroidism and Graves Disease, Hashimoto’s Triggers, and The Hyperthyroid Healing Diet, and hosts the Save My Thyroid podcast. He holds a Master’s degree in Human Nutrition and Functional Medicine and advanced certifications in nutrition and herbal therapy.

Key Topics Covered

Connect with Dr. Eric Osansky

Facebook: https://www.facebook.com/NaturalThyroidTreatment/
YouTube: https://www.youtube.com/@NaturalThyroidDoctor
Instagram: https://www.instagram.com/drericosansky/
Website: https://savemythyroid.com

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🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<<

What if the real answers to your midlife hormone struggles are not in a pill, but in understanding the deeper connections between your thyroid, metabolism, and the way your body changes over time?

In this powerhouse mashup episode, Dr. Cassie Smith brings together two of the most outspoken and experienced voices in functional medicine: McCall McPherson, thyroid expert and founder of Modern Thyroid Clinic, and Dr. Tyna Moore, a naturopathic physician and metabolic health disruptor. Together, they unpack the complex hormonal shifts women experience—especially during perimenopause and menopause—and share real-world strategies to reclaim health, energy, and vitality.

From GLP-1 medications to progesterone deficiency, thyroid misdiagnosis to strength training, this episode covers the most pressing questions women are asking today. You’ll hear personal insights, clinical wisdom, and evidence-based tools for navigating hormone changes, gut issues, inflammation, and mental health with clarity and confidence.

👤 About the Guests

McCall McPherson is the founder of Modern Thyroid Clinic and Thyroid Nation, a TEDx speaker, physician assistant, and a thyroid warrior herself. Her mission is to end the suffering of millions with thyroid disorders through expert care, patient advocacy, and empowering education.

Dr. Tyna Moore is a licensed Naturopathic Physician and Chiropractor specializing in resilient metabolic health, regenerative medicine, and clinical strength training. She's also the host of The Dr. Tyna Show and a strong advocate for women’s health and muscle-centric aging.

🔑 Key Topics Covered

📲 Follow Dr. Cassie Smith & Modern Endocrine

💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠

📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠

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🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠

📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠

➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<<

What if the key to healing your hormones has been hidden in your thought patterns all along?

In this transformational episode, Dr. Cassie Smith sits down with renowned clinical neuroscientist and communication pathologist Dr. Caroline Leaf to explore how mental health and hormonal health are deeply intertwined. They dive into the science of neuroplasticity—our brain’s ability to rewire itself—and how harnessing this power can help women break free from anxiety, depression, and hormonal imbalances.

Dr. Leaf introduces her 5-step Neurocycle™ process, explains why anxiety and depression are not diseases but signals, and shows how rewiring our thought patterns can improve everything from thyroid function to weight loss. If you've ever struggled with chronic stress, burnout, mood swings, or stubborn hormone issues, this episode offers hope, science, and practical tools to help you heal from the inside out.

👤 About the Guest:

Dr. Caroline Leaf is a clinical neuroscientist, communication pathologist, bestselling author of 19 books, and host of the award-winning podcast Cleaning Up the Mental Mess. With over 50 million downloads and a global following, Dr. Leaf is a pioneer in the field of mind-brain research and mental health. Her work bridges neuroscience, mental wellness, and functional healing through a holistic lens.

🔗 Website: www.drleaf.com

🎙️ Podcast: Cleaning Up the Mental Mess

📸 Instagram: @drcarolineleaf

🔑 Key Topics Covered:

📲 Follow Dr. Cassie Smith & Modern Endocrine

💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠

📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠

🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠

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🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠

📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠

➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<<

Could your migraines be less about pain in your head—and more about hidden imbalances in your hormones, gut, and environment?

In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith sits down with functional medicine pharmacist Dr. Meg Mill to uncover the surprising root causes of chronic migraines—especially in women navigating hormonal shifts like menstruation, perimenopause, and menopause. Together, they explore how more than 50 potential triggers can fuel migraine symptoms, from dehydration and poor sleep to gut health issues, estrogen dominance, and histamine intolerance.

Dr. Mill shares how functional medicine helps uncover these connections and provides a roadmap for lasting relief. They discuss the power of personalized migraine tracking, hormone and gut testing, and targeted protocols to reduce inflammation and rebalance the nervous system. Whether you’ve suffered for years or are newly struggling with hormone-driven headaches, this episode is a must-listen.

💡 Functional migraine solutions are within reach—no endless prescriptions required.

🔑 Key Topics Covered

👤 About the Guest: Dr. Meg Mill, PharmD, AFMCP

Dr. Meg Mill is a functional medicine pharmacist, bestselling author, and host of A Little Bit Healthier podcast. With 20+ years of clinical experience, she helps women around the world resolve migraines, hormonal issues, and histamine-related symptoms. She's the founder of the Radiant Method, which empowers women to regain energy and clarity through root-cause healing.

📍 Learn more: www.megmill.com
 🎧 Podcast: A Little Bit Healthier

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>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠<<

Could Your Period Problems Be Solved With a More Functional Approach?

In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith is joined by Dr. Shawn Tassone—known as America’s Holistic Gynecologist—for an eye-opening conversation about periods, PCOS, hormone therapy, and why women are often underserved by conventional gynecology. Together, they unpack the myths around hormonal care, discuss integrative strategies for menstrual and menopausal symptoms, and explore how stress, gut health, and even modern medical bias influence women’s health outcomes.

Dr. Tassone shares his deeply personal story of entering gynecology after watching his mother suffer from ovarian cancer, and how that journey led him to pursue a PhD in mind-body medicine and a more holistic practice. This powerful episode shines a light on the frustrations many women experience in conventional care and offers science-based, integrative solutions that truly address the root cause.

💡 Whether you're struggling with painful periods, irregular cycles, PCOS, perimenopause, or hormone confusion—this episode will leave you feeling seen, informed, and empowered.

🔑 Key Topics Covered

👨‍⚕️ About Dr. Shawn Tassone

Dr. Shawn Tassone is a double board-certified OB/GYN and integrative medicine physician, with a PhD in Mind-Body Medicine. Known as America’s Holistic Gynecologist, he has cared for over 40,000 women over two decades and is the creator of the world’s first integrative hormone mapping system. He is a national speaker, author of The Hormone Balance Bible, and a passionate advocate for patient-centered hormone care. Based in Austin, Texas, Dr. Tassone is also a frequent voice online, helping women reclaim their hormonal health through education, empowerment, and integrative care.

📘 The Hormone Balance Bible by Dr. Shawn Tassone — Amazon

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💻 Website:⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠

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➡️ Disclaimer:⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠