Should we take aspirin every day? What do we need to know about cholesterol and statins? What level of cholesterol is healthy? What is epigenetics? What is the effect of stress on our epigenetics? What is the effect of stress on our microbiome? How did therapeutic plasma exchange make mice younger and how is this technology being used for humans? 

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Dr. Michael Roizen is the Chief Wellness Officer Emeritus at Cleveland Clinic, award-winning author, and founder of RealAge. Dr. Roizen joins us to discuss his new book The Great Age Reboot, how stress impacts our health, what numbers we should aim for for cholesterol, therapeutic plasma exchange, and more. 

“Stress, it turns out, turns on genes that make proteins that cause inflammation. Moderating stress — that is, happiness — turns off those same genes and turns on genes that make anti-inflammatory proteins — proteins that decrease inflammation.” 

“The most important things are posse and purpose: having 6 friends you’re vulnerable to every month, having a purpose in life, and a job with latitude.” 

“When you exercise, you change the genes that are on in your microbiome. When you’re stressed, you change which genes are on in your microbiome.” 

“I still think you should shoot for cholesterol less than 70 in your blood.” 

“The most important things you do for brain health are posse and purpose, that’s one. The second one is to add speed to your exercise, that is to stress your muscle; and the third is to add speed to your brain games.” 

Listen to the SuperAge podcast wherever you get your pods. 

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Buy “The Great Age Reboot: Cracking the Longevity Code for a Younger Tomorrow”
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