Huberman Lab

Huberman Lab

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Huberman Lab episodes

  • Male vs. Female Brain Differences & How They Arise From Genes & Hormones | Dr. Nirao Shah

    My guest is Dr. Nirao Shah, MD, PhD, a professor of psychiatry, behavioral sciences and neurobiology at Stanford University School of Medicine. We discuss how the brains of males and females differ and how those differences arise from different genes and hormones during fetal development, in childhood and adulthood. We discuss what drives male- versus female-specific behaviors and how hormonal fluctuations across the lifespan, including puberty, the menstrual cycle, menopause and aging – affect behavior, cognition and health. Additionally, we discuss how biology relates to gender identity and the impact of hormone therapies on brain circuits that regulate mating, parenting and social bonding.

    Read the episode show notes at hubermanlab.com.

    Thank you to our sponsors

    AG1: https://drinkag1.com/huberman

    Maui Nui: https://mauinuivenison.com/huberman

    Eight Sleep: https://eightsleep.com/huberman

    LMNT: https://drinklmnt.com/huberman

    Function: https://functionhealth.com/huberman

    Timestamps

    00:00:00 Nirao Shah

    00:02:11 Mice, Humans & Brain, Biological Conservation

    00:05:25 Hormones, Nature vs Nurture

    00:07:13 Biological Sex Differences, Chromosomes & SRY Gene, Hormones

    00:16:01 Sponsors: Maui Nui & Eight Sleep

    00:19:09 Androgen Mutations, Feminization & Masculinization

    00:22:04 SRY Gene; Animals & Sexual Trans-Differentiation

    00:27:49 Hormones & Biological Brain Differentiation

    00:31:22 Congenital Adrenal Hyperplasia, Androstenedione; Stress & Pregnancy

    00:35:56 Genes, Brain Differentiation & Sexual Identity; Congenital Adrenal Hyperplasia

    00:43:37 Testosterone, Estrogen & Brain Circuits

    00:47:27 Sponsors: AG1 & LMNT

    00:50:36 Intersex Individuals, Castration

    00:52:23 Female Sexual Behavior, Brain, Testosterone & Pheromones

    00:57:58 Identify as Heterosexual or Homosexual, Difference in Hormone Levels?

    01:00:42 Gender, Sexual Orientation & Hormones; Hormone Replacement Therapy

    01:10:21 Aromatization; Steroid Hormones & Gene Expression

    01:15:00 Kids & Changing Gender Identity

    01:19:05 Sexual Behavior, Refractory Period & Male Brain, Tacr1 Cells

    01:21:31 Sponsor: Function

    01:23:19 Hypothalamus, Dopamine, Prolactin, Cabergoline, Libido, Dopamine

    01:27:05 Brain Circuits, Aggression & Sexual Behavior

    01:32:40 Refractory Period; Age, Testosterone & Libido

    01:36:07 Tacr1 Cells in Females, Periaqueductal Gray & Innate Behaviors

    01:40:00 Parenting Behaviors & Brain Circuits; Pet Dogs

    01:43:12 Oxytocin, Pair Bonding, Vasopressin; Biological Redundancy

    01:47:22 Libido, Melanocortin, Tacr1 Neurons; GLP-1 Agonists, Clinical Trials; Kisspeptin

    01:56:43 Female Brain Changes, Menstrual Cycle, Pregnancy, Menopause; Estrogen; Men & Hormone Fluctuation?

    02:04:10 Life Experience Male vs Female, Sex Recognition, Behaviors & Context

    02:16:05 Pain Management; Endocrine Disrupters, Gender Identity

    02:21:03 Future Projects

    02:24:29 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter

    Disclaimer & Disclosures

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    2 hr 27 min
  • Essentials: Psychedelics for Treating Mental Disorders | Dr. Matthew Johnson

    In this Huberman Lab Essentials episode, my guest is Dr. Matthew Johnson, PhD, a senior researcher for the Center of Excellence for Psilocybin Research and Treatment at Sheppard Pratt’s Institute for Advanced Diagnostics and Therapeutics.

    We explore the science and therapeutic potential of psychedelic medicine, including psilocybin, MDMA and LSD. We discuss how these substances can profoundly alter perception and self-identity, providing long-lasting relief from depression, addiction and trauma when used in controlled clinical settings. We also discuss microdosing and emerging research on psychedelics’ potential to support recovery from neurological injuries.

    Read the episode show notes at hubermanlab.com.

    Thank you to our sponsors

    AG1: https://drinkag1.com/huberman

    David: https://davidprotein.com/huberman

    BetterHelp: https://betterhelp.com/huberman

    Timestamps

    00:00:00 Matthew Johnson; Psychedelics

    00:01:44 Different Classes of Psychedelics

    00:04:33 Psychedelics & Altering Models

    00:06:18 Sponsor: David

    00:07:33 LSD, Psylocibin & Serotonin

    00:09:55 Psychedelic Clinical Trials

    00:13:40 Therapy, Trust, Psychedelics

    00:16:47 Letting Go & Psychedelic Experience, Self-Representation, Lasting Changes

    00:22:31 Sponsors: AG1 & BetterHelp

    00:25:26 MDMA, Dopamine & Serotonin; Bad Trips & Transcendental Experience

    00:28:49 Dangers of Psychedelics

    00:31:11 Microdosing Psychedelics, Antidepressant

    00:35:27 Head Injuries, Psychedelics, Depression

    00:38:29 Acknowledgements

    Disclaimer & Disclosures

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    40 min
  • Health Effects & Risks of Kratom, Opioids & Other Natural Occurring Medicines | Dr. Chris McCurdy

    My guest is Dr. Chris McCurdy, PhD, FAAPS, professor of medicinal chemistry at the University of Florida and a world expert on the pharmacology of kratom and other plant-derived medicinal compounds. We discuss kratom’s wide-ranging effects, including its use for boosting energy, enhancing mood, managing pain and as a potential opioid substitute, while also explaining its critical safety concerns and addictive potential, especially for kratom-derived/isolate products. We also discuss plant-based compounds more generally for their potential benefits and risks. Dr. McCurdy offers a balanced perspective on kratom and other plant-based and naturally occurring medicinal compounds, highlighting and contrasting their promise for human health with potential serious risks.

    Read the episode show notes at hubermanlab.com.

    Thank you to our sponsors

    AG1: https://drinkag1.com/huberman

    David Protein: https://davidprotein.com/huberman

    Eight Sleep: https://eightsleep.com/huberman

    ROKA: https://roka.com/huberman

    Function: https://functionhealth.com/huberman

    Timestamps

    00:00:00 Chris McCurdy

    00:02:51 Kratom (Mitragyna speciosa), Origin, Effects, Low vs High Doses

    00:07:19 Sponsors: David Protein & Eight Sleep

    00:10:07 Kratom, Traditional Use vs Commercial Kratom Products, Absorption

    00:17:00 Kratom Products, Serving Size, Kids; Semi-Synthetics; Tool: Understand Kratom Product Labels

    00:23:16 Kratom Products & Various Desired Effects; Physical Dependence

    00:32:53 Different Kratom Usage Patterns, Opioid Dependence

    00:36:59 Alkaloid Compounds, Nitrogen, Nicotine; Animals & Self-Experimentation

    00:47:47 Sponsors: AG1 & ROKA

    00:51:05 Medicine Development, Disconnection from Nature, Product Concentrations

    00:59:00 Alkaloids & Natural Products, Opium Poppy, Coca Leaf, Tool: Kratom Leaf vs Extracts (Kratom-Derived/Kratom Isolates)

    01:09:06 Is It Safe for Kids to Consume Kratom Products?

    01:12:19 Kratom, Energy, Mood & Pain Management, Dose; Caffeine

    01:16:56 Respiratory Depression & Kratom Products

    01:20:16 Sponsor: Function

    01:22:04 Kratom Leaf vs Derivatives, FDA Regulations, Usage Guidelines

    01:26:59 Kratom, Alcohol Consumption, Respiratory Failure?

    01:29:09 Kratom Alkaloids, Mood & Stimulant Effects, Multiple Pathways for Pain Relief

    01:38:17 Plant Alkaloids & Chemical Defense, Kratom & Antifungal Alkaloids; Geckos

    01:44:35 White, Red & Brown Vein Kratom, Leaf Processing; Terpenes

    01:51:08 Kratom as an Anti-Depressant?; Discontinuing Kratom Use, Opioid Use

    01:58:03 Kratom, Drug Interactions & Seizure, Opioids

    02:01:51 Cacao Beans, Chocolate

    02:09:34 Coca-Cola, Coca Plant & Cocaine, History of Soft Drinks

    02:19:49 Career Journey, Pharmacy, Chemistry & Education, Lobelia

    02:28:44 Nicotine; Natural Products & Career Journey, Salvia divinorum, Kratom

    02:40:22 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter

    Disclaimer & Disclosures

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    2 hr 45 min
  • Essentials: Healthy Eating & Eating Disorders - Anorexia, Bulimia, Binging

    In this Huberman Lab Essentials episode, I discuss both healthy eating and clinically recognized eating disorders, including anorexia, bulimia and binge eating disorder.

    I explain how brain circuits, hormones such as leptin and reward systems interact to regulate appetite, satiety and overall eating behaviors. I also discuss the serious health risks associated with anorexia, explain how disrupted eating habits contribute to its development and highlight evidence-based treatments for anorexia. Finally, I explore binge eating and bulimia, discussing the underlying causes and the pharmacological treatments commonly used to support recovery.

    Read the episode show notes at hubermanlab.com.

    Thank you to our sponsors

    AG1: https://drinkag1.com/huberman

    LMNT: https://drinklmnt.com/huberman

    Function: https://functionhealth.com/huberman

    Timestamps

    00:00:00 Eating Disorders

    00:01:05 Fasting, Intermittent Fasting, Healthy Eating

    00:06:10 Self-Diagnosis Caution

    00:07:20 Sponsor: LMNT

    00:08:52 Eating Disorders, Anorexia Nervosa

    00:12:39 Hunger & Satiety; Appetite, Body Fat & Brain

    00:17:20 Homeostasis & Reward Systems, Eating Disorders

    00:21:12 Sponsor: AG1

    00:22:49 Anorexia, Puberty, Hyperacuity & Food

    00:25:55 Decision-Making vs Reflexes/Habits, Anorexia

    00:29:29 Anorexia & Breaking Habits, Therapies & Family-Based Models

    00:32:08 Distorted Self-Image & Anorexia

    00:35:03 Sponsor: Function

    00:36:43 Bulimia & Binge-Eating Disorder, Impulsivity & Prescription Treatments

    00:40:28 Recap & Key Takeaways

    Disclaimer & Disclosures

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    45 min
  • How Nature & Other Physical Environments Impact Your Focus, Cognition & Health | Dr. Marc Berman

    My guest is Dr. Marc Berman, PhD, a professor of psychology at the University of Chicago whose research explores how different physical environments—particularly nature and patterns found in nature—can positively impact our ability to focus, our cognitive performance and our mental and physical health. We discuss how our physical environment influences our attention, stress levels and brain and heart health. He explains how even brief periods in nature and exposure to natural images and sounds can restore and improve attentional capacity, reduce mental fatigue and help combat rumination and depression. Whether you live in a city, suburb or rural area, this episode offers simple science-backed strategies for incorporating nature and natural elements into your daily life to positively transform your cognitive ability and mental and physical health.

    Read the episode show notes at hubermanlab.com.

    Thank you to our sponsors

    AG1: https://drinkag1.com/huberman

    Helix Sleep: https://helixsleep.com/huberman

    BetterHelp: https://betterhelp.com/huberman

    Our Place: https://fromourplace.com/huberman

    LMNT: https://drinklmnt.com/huberman

    Timestamps

    00:00:00 Marc Berman

    00:02:14 Direct vs Involuntary Attention, Mental Fatigue, Attention Restoration Theory

    00:06:59 Attention Fatigue, Focus & Vision, Tool: Restoring Attention in Nature

    00:11:26 Sponsors: Helix Sleep & BetterHelp

    00:13:50 Focused Work, Tool: Pre-Work Nature Breaks to Enhance Focus

    00:15:54 Nature Walks & Cognitive Benefits, Comparing Nature vs Urban Environments

    00:21:31 Nature, “Softly Fascinating Stimulation”, Fractals

    00:27:12 Nature Images & Sounds, Cognitive Benefits

    00:30:03 Urban vs Nature Images, Complexity & Image Compression; Semantics

    00:40:44 Time Perception & Nature; Art Galleries

    00:45:32 Tools: Resetting Attention & Nature Break; Features of a Restorative Nature Environments vs Focused Workspace; Length of Time in Nature

    00:52:47 Sponsors: AG1 & Our Place

    00:55:59 Nature, Time & Widening Attention; Fractals & Nature

    01:02:21 Nature vs Urban Environments & Brain, Social Media & Attention

    01:09:44 Depression & Rumination, Mental Well-Being, Attention & Nature

    01:14:56 Sleep vs Wakefulness; Protecting Attention, Social Media

    01:24:44 Sponsor: LMNT

    01:26:19 Impulsivity, Texting & Attention, Meditation vs Nature Restoration

    01:33:10 Passive Restorative vs Passive Depleting Activities, “Mental Obesity”, Shrinking Attention Span

    01:37:31 Kids, Phones, Tool: Nature Free Play; Social Happy Hour, Tool: Solitary Nature Breaks

    01:45:30 Physical Health Benefits of Nature, Trees & Indoor Greenery; Aquariums

    01:53:26 Thoughts, Feelings & Physical Spaces, Biophilic Design, Bringing Nature Indoors

    02:01:03 Nature Breaks, Incorporating Nature into Schools, Work, Home & Cities; Forest Bathing

    02:09:18 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter

    Disclaimer & Disclosures

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    2 hr 12 min
  • Essentials: Science of Stress, Testosterone, Aggression & Motivation | Dr. Robert Sapolsky

    In this Huberman Lab Essentials episode my guest is Dr. Robert Sapolsky, PhD, a professor of biology, neurology and neurological sciences at Stanford University.  

    We discuss different types of stress and how our perception of stress as harmful or beneficial largely depends on context. He also explains how testosterone amplifies pre-existing behaviors and tendencies, and he highlights the crucial role of estrogen in supporting brain and body health. We also discuss daily cognitive practices for stress mitigation and how modern life, influenced by social media and complex social hierarchies, shapes our responses to stress.

    Read the episode show notes at hubermanlab.com.

    Thank you to our sponsors

    AG1: https://drinkag1.com/huberman

    Function: https://functionhealth.com/huberman

    LMNT: https://drinklmnt.com/huberman

    David: https://davidprotein.com/huberman

    Timestamps

    00:00:00 Robert Sapolsky

    00:00:23 Positive & Negative Stress; Excitement, Amygdala

    00:02:47 Testosterone & Brain, Aggression, Hierarchy

    00:06:27 Sponsors: Function & LMNT

    00:09:18 Testosterone, Motivation, Challenge & Confidence

    00:13:52 Dopamine, Testosterone & Motivation

    00:16:20 Estrogen, Brain & Health, Replacement Therapies

    00:18:12 Stress Mitigation

    00:22:09 Sponsors: AG1 & David

    00:24:59 Cognitive Practices for Stress Mitigation, Individual Variability, Consistency

    00:27:18 Stress, Perception & Individual Differences

    00:29:39 Context, Stress & Brain

    00:32:47 Social Media, Context, Multiple Hierarchies

    00:35:57 Acknowledgments

    Disclaimer & Disclosures

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    37 min
  • How to Lose Fat & Gain Muscle With Nutrition | Alan Aragon

    My guest is Alan Aragon, a renowned nutrition and fitness expert and researcher known for sharing the strongest evidence-based approaches to fat loss, muscle gain and overall health and fitness. We discuss how to optimize your protein intake, including how much to consume per meal and when, and the facts and myths about the “30-gram rule” and the “anabolic window” following exercise. We also discuss controversial topics such as seed oils, artificial sweeteners, animal vs. plant proteins, training fasted for fat loss and collagen supplementation. Alan Aragon clarifies the most important topics in nutrition and offers valuable time-saving yet extra-effective ways to exercise. He is a true expert in providing data-supported actionable exercise and nutrition protocols for anyone seeking to improve their body composition and health.

    Read the episode show notes at hubermanlab.com.

    Thank you to our sponsors

    AG1: https://drinkag1.com/huberman

    Carbon: https://joincarbon.com/huberman

    Wealthfront**: https://wealthfront.com/huberman

    David: https://davidprotein.com/huberman

    Function: https://functionhealth.com/huberman

    **This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27,‬ 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable‭ APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer.

    Timestamps

    00:00:00 Alan Aragon

    00:02:17 Dietary Protein & Protein Synthesis Limits?, Tool: Post-Resistance Training & Protein Intake (30-50g)

    00:09:16 Training Fasted, Post-Exercise Anabolic Window, Tool: Total Daily Protein

    00:15:53 Daily Protein Intake, Timing & Exercise, Muscle Strength/Size

    00:23:00 Sponsors: Carbon & Wealthfront

    00:26:46 Does Fasted Training Increase Body Fat Loss?, Cardio, Individual Flexibility

    00:36:53 Dietary Protein & Body Composition

    00:38:58 Animal vs Plant Proteins (Whey, Soy, Pea, Quorn), Muscle Size & Strength

    00:51:24 Sponsors: AG1 & David

    00:54:14 Body Re-Composition, Gain Muscle While Losing Fat?, Tool: Protein Intake & Exercise

    01:02:55 Fiber; Starchy Carbohydrates & Fat Loss, Ketogenic Diet

    01:10:36 Inflammation, Fat & Macronutrients, Hyper-Palatability; Fish Oil Supplementation

    01:16:52 Added Dietary Sugars, Sugar Cravings, Tool: Protein Intake

    01:24:03 Artificial Sweeteners (Aspartame, Sucralose, Saccharine, Stevia), Diet Soda, Weight Loss

    01:30:16 Sponsor: Function

    01:32:04 Caffeine, Exercise & Fat Loss

    01:34:53 Alcohol, Red Wine, Sleep, Lifestyle; Quitting Drinking & Stress Resilience

    01:44:43 Seed Oils vs Animal Fats, Canola Oil, Olive Oil, Oil Production, Tool: Improve Diet Quality

    01:55:50 Butter & Cardiovascular Risk, Saturated Fat, Mediterranean Keto Diet, Testosterone

    02:00:43 Menstrual Cycle, Tool: Diet Breaks; Menopause Transition & Body Composition

    02:07:04 Collagen Supplementation, Skin Appearance

    02:12:44 Supplements: Multivitamins, Vitamin D3, Fish Oil, Creatine, Vitamin C

    02:20:03 Resistance & Cardio Training, Tool: Cluster Sets & Super Sets

    02:31:35 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter

    Disclaimer & Disclosures

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    2 hr 36 min
  • Essentials: Understanding & Conquering Depression

    In this Huberman Lab Essentials episode, I explore major depression, including its underlying biology and discuss science-based approaches to alleviate symptoms and improve mood.

    I describe the wide-ranging symptoms of depression and explain how key neurotransmitters, hormones, stress, genetics and inflammation contribute to its development and persistence. I also cover treatment options, from traditional classes of antidepressant medications to emerging therapies such as ketamine and psilocybin. Finally, I highlight lifestyle-based tools, including exercise, supplementation and dietary strategies that can help manage depressive symptoms and promote mental well-being.

    Read the episode show notes at hubermanlab.com.

    Thank you to our sponsors

    AG1: https://drinkag1.com/huberman

    BetterHelp: https://betterhelp.com/huberman

    Our Place: https://fromourplace.com/huberman

    Timestamps

    00:00:00 Major Depression

    00:01:10 Depression Symptoms

    00:06:14 Sponsor: BetterHelp

    00:07:33 Pharmaceuticals for Depression, SSRIs; Norepinephrine, Dopamine & Serotonin

    00:14:33 Thyroid Hormone, Cortisol, Stress & Depression, Menstrual Cycle, Genetics

    00:17:43 Sponsor: AG1

    00:19:20 Increase Norepinephrine, Tools: Deliberate Cold Exposure & Exercise

    00:21:40 Chronic Inflammation & Depression, Tools: Omega-3s (EPA) & Exercise

    00:26:49 Sponsor: Our Place

    00:28:41 Tool: Creatine Monohydrate Supplementation & Improving Depression

    00:30:20 Novel Depression Therapies, Ketamine, Psilocybin

    00:35:29 Ketogenic Diet & Refractory Depression, GABA

    00:37:57 Recap & Key Takeaways

    Disclaimer & Disclosures

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    41 min
  • The Chemistry of Food & Taste | Dr. Harold McGee

    Dr. Harold McGee, PhD, is a renowned author on the topics of food chemistry and culinary science. He explains how cooking methods, types of cookware and temperature can be used to transform food and drink flavors and presents simple but powerful ways to improve nutrient availability. We also discuss how our individual biology, genetic and cultural backgrounds shape our taste preferences. Whether you’re a seasoned cook or someone who simply loves to eat, our conversation will change how you think about food and cooking, give you actionable tools to try and deepen your appreciation of the experience of eating and drinking.

    Read the episode show notes at hubermanlab.com.

    Thank you to our sponsors

    AG1: https://drinkag1.com/huberman

    Eight Sleep: https://eightsleep.com/huberman

    Our Place: https://fromourplace.com/huberman

    Mateina: https://drinkmateina.com/huberman

    Function: https://functionhealth.com/huberman

    Timestamps

    00:00:00 Harold McGee

    00:02:21 Food Chemistry, Using Copper, Modern vs Traditional Techniques

    00:09:59 Sponsors: Eight Sleep & Our Place

    00:13:33 Cooking, Food & Heat, Taste & Smell

    00:22:10 Umami, Savory Tastes, Braising & Meat

    00:29:56 Chemistry of Cooking & Eating, Sugars & Conjugates; Slowly Enjoying Food

    00:36:14 Savory Meal & Dessert; Food Course Order; Palate Cleansers

    00:43:56 Salt, Baseline & Shifting Taste Preferences

    00:47:18 Sponsors: AG1 & Mateina

    00:50:07 Whole vs Processed Foods, Taste & Enjoyment

    00:53:37 Brewing Coffee, Water Temperature, Grind Size

    01:00:33 Tea & Tannins, Growing Tea Plants; Tea & Meals, Polyphenols

    01:08:16 Food Combinations, Individual Tolerance; Is there an Optimal Diet?

    01:11:34 Onions & Garlic, Histamines, Tool: Reduce Crying when Cutting Onions

    01:13:55 Gut Sensitivities & Food, Capsaicin & Spicy Foods

    01:17:21 Supertasters & Taste Buds, Bitter Taste, Chefs

    01:21:57 Sponsor: Function

    01:23:45 Salt & Bitter, Salting Fruit, Beer or Coffee, Warming Beer

    01:26:11 Human History of Alcohol & Chocolate

    01:29:25 Wine Expense vs Taste, Wine Knowledge

    01:35:49 Cheese Making, Aged Cheese & Crystals, Tyrosine; Smoke Flavors, Distilling

    01:44:30 Fermentation, “Stink Fish”, Caviar, Traditional & New Foods

    01:50:42 Personal Journey, Astronomy, Poetry & Food

    01:54:55 Beans & Gas, Tool: Soaking Beans

    01:57:23 Gut Microbiome, Fermented Foods; Kids & Food Aversions

    02:00:47 Cilantro & Divergent Tastes; Microwave Popcorn, Parmesan Cheese

    02:04:46 John Keats Poetry, To Autumn; Acknowledgements

    02:10:48 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter

    Disclaimer & Disclosures

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    2 hr 14 min
  • Essentials: Understanding & Treating Addiction | Dr. Anna Lembke

    In this Huberman Lab Essentials episode, my guest is Dr. Anna Lembke, MD, Chief of the Stanford Addiction Medicine Dual Diagnosis Clinic at Stanford University School of Medicine.

    We discuss how dopamine drives reward, motivation and addictive behaviors. Dr. Lembke explains the concept of the pleasure-pain balance of dopamine and how this cycle plays a key role in the development and persistence of addiction. We also discuss some of the challenges of addiction recovery, including withdrawal, relapses and the potential benefits of psychedelic-assisted therapy.

    Read the episode show notes at hubermanlab.com.

    Thank you to our sponsors

    AG1: https://drinkag1.com/huberman

    Wealthfront**: https://wealthfront.com/huberman

    BetterHelp: https://betterhelp.com/huberman

    **This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27,‬ 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable‭ APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer.

    Timestamps

    00:00:00 Anna Lembke

    00:00:15 Dopamine, Reward & Movement

    00:01:54 Baseline Dopamine; Genetics, Temperament & Addiction

    00:05:24 Addiction, Modern Life & Boredom

    00:07:18 Sponsor: AG1

    00:08:55 Pleasure-Pain Balance, Dopamine, Addiction

    00:14:17 Resetting Dopamine, Substance or Behavior Recovery, Tool: 30-Day Abstinence

    00:16:04 Relapse, Addiction, Reflexive Behavior, Empathy

    00:20:17 Triggers, Relapse, Dopamine

    00:23:15 Sponsor: Wealthfront & BetterHelp

    00:26:04 Shame, Truth Telling & Recovery

    00:28:26 Addiction, Psychedelic-Assisted Therapy, Psilocybin, MDMA

    00:33:29 Social Media & Addiction, Tool: Intentionality

    Disclaimer & Disclosures

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    37 min

About Huberman Lab

From the publisher's feed

The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works.

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