📣 Software engineer turned metabolic health researcher Dave Feldman joins Ketobiography host Robyn Dobbins to unpack what has happened since the release of the Keto CTA study — the data, the controversy, and what four analyses of the same 200 scans are now showing about LDL, plaque progression, and heart health.
📋 Dave walks through the full arc: the study methodology, the unexpected questions raised by the Clearly AI data set, the blinded HeartFlow and QAngio analyses that followed, and what plaque regression findings mean for lean mass hyper-responders. He also shares updates on The Feldman Protocol podcast and the Cholesterol Code documentary.
🔑 What You'll Learn
- How the Keto CTA study was designed, crowdfunded, and executed across 100 participants with two CT angiography scans each.
- Why the Clearly AI quantitative analysis raised serious questions — including the absence of any plaque regression across all 100 participants — and what Dave did about it.
- How HeartFlow and QAngio, analyzed with fully blinded data, produced results consistent with the semiquantitative analysis and with each other.
- What plaque regression findings mean for lean mass hyper-responders and why the absence of an LDL-plaque association held across every analytical approach.
- What comes next: five-year follow-up scans, the Triad study with a control group, and the possibility of a randomized controlled trial.
💡 Key Insight
"Science isn't about having all the answers immediately — it's about facing tough questions and letting the truth emerge through open conversation." — Dave Feldman
🌐 Connect with Dave Feldman
Website: https://www.cholesterolcode.com
The Feldman Protocol Podcast: https://pod.link/1836440704
X: https://x.com/realDaveFeldman
YouTube: https://www.youtube.com/@realDaveFeldman
The Feldman Protocol: https://www.youtube.com/@FeldmanProtocol
🔬 Resources
Keto CTA Study (JACC): https://www.jacc.org/doi/10.1016/j.jacadv.2025.101686
Preliminary QAngio Data — Rapid Progressors: https://youtu.be/ZrH8pqTiyoc
Keto CTA Update — Cleerly Clarification: https://youtu.be/aJobOSRdIOM
Citizen Science Foundation: https://citizensciencefoundation.org
CoSci Conference: https://cosci.org
🎥 The Cholesterol Code: https://cholesterolcodemovie.com
⚕️ This podcast is for informational and educational purposes only and is not medical advice; always consult a qualified healthcare professional about your own health decisions.
⏳ Chapters
0:47 Introduction and host welcome
2:50 The spark behind the Keto CTA study
4:50 CT angiography explained and study design
7:48 Baseline and longitudinal scan results
8:53 Semiquantitative vs quantitative data analysis
12:50 Data challenges and the Clearly anomaly
18:47 Social media rollout and public response
25:52 Engaging HeartFlow and validating the data
30:49 Plaque regression findings and what they mean
42:52 Five-year scans and the Triad study
47:52 The Feldman Protocol podcast
50:51 Cholesterol Code documentary update
🎧 New episodes drop every Thursday on YouTube, Apple Podcasts, Spotify, and all major platforms.
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👥 Connect with Robyn:
https://www.robyndobbins.com
https://linktr.ee/robyn.r.dobbins
🎬 Robyn is featured in The Cholesterol Code – Watch it on Amazon.
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