When nurse and midwife Agnes Nisbett’s third baby was delivered, she was confronted by a profound need for systemic change. Agnes came to the UK as part of the Windrush generation and despite many barriers, “sheer hard work” got her to the top of her profession. However, her own hospital experience in the 1970s revealed just how flawed and uncaring the system could be.

Now in her 80s, Agnes looks back on her time in the NHS, and shares with Dr Sian Williams how her personal loss inspired her to challenge and change things for others.

Warning: This interview discusses the experience of stillbirth. Details of help and support with pregnancy-related issues are available through the BBC Action Line at bbc.co.uk/actionline.

Georgia Gabriel-Hooper is now 20, she works for a tractor dealership and enjoys bumbling around the countryside. But as a child, she was witness to a terrible event: her mother, Cheryl, was murdered in a domestic homicide. Understandably, that day had a profound impact on Georgia – who has since shown extraordinary courage and determination to use her personal testimony to raise awareness and create change around domestic abuse.

Georgia tells her story to Dr Sian Williams.

If you, or someone you know, has been affected by domestic abuse or violence, you can find details of support available on the BBC Action Line at bbc.co.uk/actionline. If you are in immediate danger, you should dial 999.

In this special edition of Life Changing, recorded in front of a live audience at the Hay Festival, we are catching up with Harriet Ware-Austin, who was a guest on the programme in 2021.

Harriet had a difficult but important story to tell, concerning the deaths of her two sisters in a plane crash in Addis Ababa in April 1972. Harriet was only eight at the time and witnessed the event. Almost 50 years on, Harriet joined us to talk about the profound and long-lasting effects it had on her family. She also wanted to see if there was anyone else out there who had a connection to East African Airways Flight 720, but was totally unprepared for the extraordinary response her interview received.

Two years later, this is the story of what happened after that interview and how it has been life-changing all over again.

You can hear Harriet’s original interview here: https://www.bbc.co.uk/programmes/m000v8w8

Growing up in Newport with his mum and younger brother, Connor Allen struggled with his identity as a mixed race kid. He bottled up his feelings and as the anger and frustration built up, could not find the words to express his emotions. When his rage erupted into violence against his mum, she ended up doing the unthinkable and calling the police. He faced a prison sentence, his future at a crossroads.

Connor tells his story to Dr Sian Williams in front of a live audience at the Hay Festival in May 2023.

When Alan and Irene met in 1959, their connection was instant. The two isolated children aged just seven and nine found warmth and kindness in each other in a children’s home that was unwelcoming and strict. They would steal moments together up on Bunny Hill and talk about their lives. But the home had a rule that boys and girls could not mix. So when their friendship was discovered, a year after they first met, Alan and Irene were separated. It would take four decades for them to find each other again.

Many years later, Irene and Alan tell their story to Dr Sian Williams.

In August of 2006, Teresa Clark was driving five of her friends back home after a day at a music festival. Several hours into the journey she fell asleep at the wheel of their people carrier and crashed. Three passengers were killed, two others were injured as well as Teresa herself.

She was convicted of causing death by dangerous driving and spent time in prison. The guilt and shame of carrying that loss of life almost destroyed her. But in the 17 years since it happened Teresa has rebuilt; she now works in the mental health and wellbeing sector trying to keep the vow she made to live her life for her friends, and do some good in their memory.

She tells Dr Sian Williams how she has rebuilt her life in the years since - keeping the vow she made to live her life for her friends, and do some good in their memory.

Details of support with mental health issues and bereavement are available at bbc.co.uk/actionline.

Ambitious police officer Clodagh Dunlop, 35, was used to dealing with emergency situations - until it was her own. Whilst training to run a 6-minute mile, her journey took a terrifying turn. Clodagh found herself trapped in her own body, hearing the conversations around her but unable to communicate.

Speaking with Dr Sian Williams, she explains how she found the strength to make a remarkable breakthrough.

Rachel Watkyn’s upbringing was a contradiction: aristocratic but impoverished. She was forced to memorise her father’s extensive family tree and was expected to behave as the 'perfect young baroness'. Despite their status, the family did not have clean clothes or heating and she was called a ‘fleabag’ by other children at school. This left Rachel isolated, never knowing where she fitted in, and feeling not good enough. Years later, when Rachel was in her 50s, her father became unwell and made a startling revelation on his deathbed.

Rachel tells her remarkable story to Dr Sian Williams.

When Will Darby left school in 2007, his peers all headed to university. But Will wanted something different – an adventure. In search of unridden waves to surf, he built himself an idyllic life in the Solomon Islands. Until the sea disappeared, and everything came crashing down…

Will tells Dr Sian Williams about the turn of events that created a lifelong bond with the island and its inhabitants.

It is the summer of 2008, and a bride and groom have just stepped out of a carriage drawn by two white horses. The sun is out, the bridesmaids are wearing beautiful dresses, and everyone has drinks in hands. The day has gone smoothly for the wedding party. But for carriage driver Emily King – things are about to take a terrifying turn, as a chase begins.

Years later, Emily tells Dr Sian Williams how she fought to survive – and why the scarring incident gave her “superpowers”.

Details of help and support are available through the BBC Action Line at bbc.co.uk/actionline.